Search Results - "Kóczián, Kristóf"

A systematic review of health economic models and utility estimation methods in schizophrenia by Németh, Bertalan, Fasseeh, Ahmad, Molnár, Anett, Bitter, István, Horváth, Margit, Kóczián, Kristóf, Götze, Árpád, Nagy, Balázs

“…There is a growing need for economic evaluations describing the disease course, as well as the costs and clinical outcomes related to the treatment of…”
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Microspeciation of amphoteric molecules of unusual acid-base properties by Kóczián, Kristóf

“…The phisico-chemical properties of bio- and drug molecules greatly influence their interactions in the body and strongly effect the mechanism of drug action…”
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Direct healthcare cost of schizophrenia – European overview by Kovács, G., Almási, T., Millier, A., Toumi, M., Horváth, M., Kóczián, Kristóf, Götze, Á., Kaló, Z., Zemplényi, A.T.

“…To provide an overview on the magnitude of the impact of schizophrenia on the healthcare system in Europe and to gain a better understanding on the most…”
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Using informative prior based on expert opinion in Bayesian estimation of the transition probability matrix in Markov modelling-an example from the cost-effectiveness analysis of the treatment of patients with predominantly negative symptoms of schizophrenia with cariprazine by Vokó, Zoltán, Bitter, István, Mersich, Beatrix, Réthelyi, János, Molnár, Anett, Pitter, János G, Götze, Árpád, Horváth, Margit, Kóczián, Kristóf, Fonticoli, Laura, Lelli, Filippo, Németh, Bertalan

“…When patient health state transition evidence is missing from clinical literature, analysts are inclined to make simple assumptions to complete the transition…”
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Quality-adjusted life year difference in patients with predominant negative symptoms of schizophrenia treated with cariprazine and risperidone by Németh, Bertalan, Molnár, Anett, Akehurst, Ron, Horváth, Margit, Kóczián, Kristóf, Németh, György, Götze, Árpád, Vokó, Zoltán

“…Our study aimed at estimating differences in quality-adjusted life year (QALY) gain for patients with predominant negative symptoms of schizophrenia treated…”
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Cost-utility analysis of cariprazine compared to risperidone among patients with negative symptoms of schizophrenia by Németh, Bertalan, Bendes, Rita, Nagy, Balázs, Götze, Árpád, Kóczián, Kristóf, Horváth, Margit, Deák, Izabella, Tóth, Bernadett, Kaló, Zoltán

“…•We investigated the subgroup of patients with negative symptoms of schizophrenia.•A Markov cohort model was built to support our analysis.•Cariprazine…”
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Column selection for pharmaceutical analyses based on a column classification using four test parameters by Kóczián, Kristóf, Haghedooren, Erik, Dragovic, Sanja, Noszál, Béla, Hoogmartens, Jos, Adams, Erwin

“…This paper focuses on the usability of a previously developed column classification system, applied to pharmaceutical analyses. The separation of two drugs…”
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Facilitated column selection in pharmaceutical analyses using a simple column classification system by Visky, Dóra, Haghedooren, Erik, Dehouck, Pieter, Kovács, Zsuzsanna, Kóczián, Kristof, Noszál, Béla, Hoogmartens, Jos, Adams, Erwin

“…In this paper, the performance of a previously developed classification system applied to pharmaceutical chromatographic analyses, is investigated. The…”
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Novel Chemical Transformations of Tenoxicam by Kóczián, Kristóf, Kökösi, József, Mazák, Károly, Noszál, Béla

“…Both N‐ and O‐substituted derivatives of the anti‐inflammatory drug tenoxicam (= 4‐hydroxy‐2‐methyl‐N‐(pyridin‐2‐yl)‐2H‐thieno[2,3‐e]…”
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Bioisosteric hybrids of two anti-inflammatory agents, rutaecarpine and piroxicam by Bubenyák, Máté, Noszál, Béla, Kóczián, Kristóf, Takács, Mária, Béni, Szabolcs, Hermecz, István, Kökösi, József

“…Bioisosteric replacements were accomplished by building the structural elements of piroxicam, an anti-inflammatory drug, into the pentacyclic system of…”
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Site-Specific Acid-Base Properties of Tenoxicam by Kóczián, Kristóf, Völgyi, Gergely, Kökösi, József, Noszál, Béla

“…The Hammett approach, as a new deductive tool, was introduced to characterize the otherwise inaccessible minor protonation pathway of tenoxicam (1), the…”
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Site-specific protonation microequilibria of penicillin and cephalosporin beta-lactam core molecules by KOCZIAN, Kristof, SZAKACS, Zoltdn, KÖKÖSI, Jozsef, NOSZAL, Béla

“…Acid-base chemistry of 6-aminopenicillanic acid (6-APA) and 7-aminocephalosporanic acid (7-ACA), the fundamental units of the two classical antibiotic families…”
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Finding an Alternative Column for the Separation of Antibiotics on XTerra RP using a Column Classification System by Haghedooren, Erik, Kóczián, Kristóf, Huang, Shan, Dragovic, Sanja, Noszál, Béla, Hoogmartens, Jos, Adams, Erwin

“…A project to develop a test procedure to characterize reversed-phase liquid chromatographic C 18 columns was started earlier and resulted in a fast, simple,…”
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