Search Results - "Kékesi, László"
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Design and synthesis of new imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrazine derivatives with antiproliferative activity against melanoma cells
Published in European journal of medicinal chemistry (27-01-2016)“…Melanoma is an aggressive form of skin cancer and it is generally associated with poor prognosis in patients with late-stage disease. Due to the increasing…”
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Lead selection and characterization of antitubercular compounds using the Nested Chemical Library
Published in Tuberculosis (Edinburgh, Scotland) (01-06-2015)“…Summary Discovering new drugs to treat tuberculosis more efficiently and to overcome multidrug resistance is a world health priority. To find novel…”
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Synthesis and biological evaluation of novel pyrido[2,3-b]pyrazines inhibiting both erlotinib-sensitive and erlotinib-resistant cell lines
Published in Bioorganic & medicinal chemistry letters (15-11-2013)“…A series of novel pyrido[2,3-b]pyrazines were synthesized as potential antitumor agents for erlotinib-resistant tumors. Known signal inhibitor compounds from…”
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Pyrido[2,3-bpyrazines inhibiting both erlotinib-sensitive and erlotinib-resistant cell lines, and their preparation via regioselective condensation reaction
Published in Acta pharmaceutica Hungarica (2014)“…The EGFR inhibitor erlotinib possesses high anti-tumor effect but despite the good clinical responses in most of the cases recrudescence occures. This can be…”
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Signal transduction therapy of cancer with kinase inhibitors
Published in Current opinion in biotechnology (01-07-2013)Get full text
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