Search Results - "Kåreholt, I."

Serum cholesterol changes after midlife and late-life cognition : Twenty-one-year follow-up study by SOLOMON, A, KAREHOLT, I, NGANDU, T, WINBLAD, B, NISSINEN, A, TUOMILEHTO, J, SOININEN, H, KIVIPELTO, M

“…Longitudinal studies have shown that high serum total cholesterol (TC) at midlife is a risk factor for dementia/Alzheimer disease. The significance of TC later…”
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Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study by Hooshmand, B., Solomon, A., Kåreholt, I., Rusanen, M., Hänninen, T., Leiviskä, J., Winblad, B., Laatikainen, T., Soininen, H., Kivipelto, M.

“…  Hooshmand B, Solomon A, Kåreholt I, Rusanen M, Hänninen T, Leiviskä J, Winblad B, Laatikainen T, Soininen H & Kivipelto M (Aging Research Center, Karolinska…”
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Homocysteine and holotranscobalamin and the risk of Alzheimer disease: A longitudinal study by HOOSHMAND, B, SOLOMON, A, KAREHOLT, I, LEIVISKÄ, J, RUSANEN, M, AHTILUOTO, S, WINBLAD, B, LAATIKAINEN, T, SOININEN, H, KIVIPELTO, M

“…To examine the relation between serum levels of homocysteine (tHcy) and holotranscobalamin (holoTC), the active fraction of vitamin B12, and risk of incident…”
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Personality and lifestyle in relation to dementia incidence by WANG, H.-X, KARP, A, HERLITZ, A, CROWE, M, KAREHOLT, I, WINBLAD, B, FRATIGLIONI, L

“…High neuroticism has been associated with a greater risk of dementia, and an active/socially integrated lifestyle with a lower risk of dementia. The aim of the…”
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Association between mid‐ to late life physical fitness and dementia: evidence from the CAIDE study by Kulmala, J., Solomon, A., Kåreholt, I., Ngandu, T., Rantanen, T., Laatikainen, T., Soininen, H., Tuomilehto, J., Kivipelto, M.

“…Objectives This study investigated the association between perceived physical fitness at midlife, changes in perceived fitness during the three decades from…”
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Antidepressants and mortality risk in a dementia cohort: data from SveDem, the Swedish Dementia Registry by Enache, D., Fereshtehnejad, S.-M., Kåreholt, I., Cermakova, P., Garcia-Ptacek, S., Johnell, K., Religa, D., Jelic, V., Winblad, B., Ballard, C., Aarsland, D., Fastbom, J., Eriksdotter, M.

“…Background The association between mortality risk and use of antidepressants in people with dementia is unknown. Objective To describe the use of…”
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Serum total cholesterol, statins and cognition in non-demented elderly by Solomon, A, Kåreholt, I, Ngandu, T, Wolozin, B, MacDonald, S.W.S, Winblad, B, Nissinen, A, Tuomilehto, J, Soininen, H, Kivipelto, M

“…Abstract Background The association between serum total cholesterol (TC), lipid-lowering drugs and cognition in the elderly is currently controversial…”
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Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease by Rovio, Suvi, Kåreholt, Ingemar, Helkala, Eeva-Liisa, Viitanen, Matti, Winblad, Bengt, Tuomilehto, Jaakko, Soininen, Hilkka, Nissinen, Aulikki, Kivipelto, Miia

“…Physical activity may help maintain cognitive function and decrease dementia risk, but epidemiological findings remain controversial. The aim of our study was…”
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Diurnal cortisol, neuroinflammation, and neuroimaging visual rating scales in memory clinic patients by Holleman, Jasper, Daniilidou, Makrina, Kåreholt, Ingemar, Aspö, Malin, Hagman, Göran, Udeh-Momoh, Chinedu T., Spulber, Gabriela, Kivipelto, Miia, Solomon, Alina, Matton, Anna, Sindi, Shireen

“…•Cortisol & neuroinflammation interacted in their relation to neuroimaging correlates.•Greater angiogenesis marker levels associated with more severe white…”
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Daytime Sleepiness, Apnea, Neuroimaging Correlates and Cortisol Dysregulation in a Memory Clinic Cohort by Sørensen, Charlotte, Kåreholt, I., Kalpouzos, G., Udeh-Momoh, C. T., Holleman, J., Aspö, M., Hagman, G., Spulber, G., Kivipelto, M., Solomon, A., Sindi, S.

“…Background Sleep disturbances as well as cortisol hypersecretion are increasingly acknowledged as risk factors for Alzheimer’s disease (AD). However, the…”
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Cognitive reserve, cortisol, and Alzheimer's disease biomarkers: A memory clinic study by Yerramalla, Manasa Shanta, Darin‐Mattsson, Alexander, Udeh‐Momoh, Chinedu T, Holleman, Jasper, Kåreholt, Ingemar, Aspö, Malin, Hagman, Göran, Kivipelto, Miia, Solomon, Alina, Marseglia, Anna, Sindi, Shireen

“…INTRODUCTION Cognitive reserve might mitigate the risk of Alzheimer's dementia among memory clinic patients. No study has examined the potential modifying role…”
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Occupational complexity and cognition in the FINGER multidomain intervention trial by Rydström, Anders, Darin‐Mattsson, Alexander, Kåreholt, Ingemar, Ngandu, Tiia, Lehtisalo, Jenni, Solomon, Alina, Antikainen, Riitta, Bäckman, Lars, Hänninen, Tuomo, Laatikainen, Tiina, Levälahti, Esko, Lindström, Jaana, Paajanen, Teemu, Havulinna, Satu, Peltonen, Markku, Sindi, Shireen, Soininen, Hilkka, Neely, Anna Stigsdotter, Strandberg, Timo, Tuomilehto, Jaakko, Kivipelto, Miia, Mangialasche, Francesca

“…Introduction Lifetime exposure to occupational complexity is linked to late‐life cognition, and may affect benefits of preventive interventions. Methods In the…”
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The Role of Brain Integrity in the Association between Occupational Complexity and Cognitive Performance in Subjects with Increased Risk of Dementia by Rydström, Anders, Stephen, Ruth, Kåreholt, Ingemar, Darin Mattsson, Alexander, Ngandu, Tiia, Lehtisalo, Jenni, Bäckman, Lars, Kemppainen, Nina, Rinne, Juha, Sindi, Shireen, Soininen, Hilkka, Vanninen, Ritva, Solomon, Alina, Mangialasche, Francesca

“…Mechanisms underlying the positive association between occupational mental demands and late-life cognition are poorly understood. The objective of this study…”
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White matter abnormalities mediate the association between masticatory dysfunction and cognition among older adults by Hedberg, Linn, Kumar, Abhishek, Skott, Pia, Smedberg, Jan‐Ivan, Seiger, Åke, Sandborgh‐Englund, Gunilla, Nordin, Love Engström, Kåreholt, Ingemar, Tzortzakakis, Antonios, Westman, Eric, Trulsson, Mats, Ekman, Urban

“…Abstract Background Masticatory parameters, such as reduced number of teeth and posterior contacts, have been shown to be associated with reduced cognitive…”
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Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms by Besga, A., Cedazo-Minguez, A., Kåreholt, I., Solomon, A., Björkhem, I., Winblad, B., Leoni, V., Hooshmand, B., Spulber, G., Gonzalez-Pinto, A., Kivipelto, M., Wahlund, L.O.

“…► This study investigates the pathogenesis of WMHs in elderly with memory complaints. ► Combined quantitative metabolic analysis and brain MRIs. ► The median…”
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Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study by Anttila, Tiia, Helkala, Eeva-Liisa, Viitanen, Matti, Kåreholt, Ingemar, Fratiglioni, Laura, Winblad, Bengt, Soininen, Hilkka, Tuomilehto, Jaakko, Nissinen, Aulikki, Kivipelto, Miia

“…Abstract Objective To evaluate the relation between midlife alcohol consumption and mild cognitive impairment and dementia in old age, and the possible…”
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Longitudinal study of Alzheimer's disease biomarkers, allostatic load, and cognition among memory clinic patients by Adedeji, Dickson O., Holleman, Jasper, Juster, Robert-Paul, Udeh-Momoh, Chinedu T., Kåreholt, Ingemar, Hagman, Göran, Aspö, Malin, Adagunodo, Sofia, Håkansson, Krister, Kivipelto, Miia, Solomon, Alina, Sindi, Shireen

“…Allostatic load (AL) is defined as the cumulative dysregulation of neuroendocrine, immunological, metabolic, and cardiovascular systems that increases the…”
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Antidepressants and mortality risk in a dementia cohort – data from SveDem, the Swedish Dementia Registry by Enache, D, Fereshtehnejad, S.M, Cermakova, P, Garcia-Ptacek, S, Kåreholt, I, Johnell, K, Religa, D, Jelic, V, Winblad, B, Ballard, C, Aarsland, D, Fastbom, J, Eriksdotter, M

“…Background The association between mortality risk and use of antidepressants in people with dementia is unknown. Objective To describe the use of…”
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Cortisol, cognition and Alzheimer’s disease biomarkers among memory clinic patients by Holleman, Jasper, Adagunodo, Sofia, Kåreholt, Ingemar, Hagman, Göran, Aspö, Malin, Udeh-Momoh, Chinedu T, Solomon, Alina, Kivipelto, Miia, Sindi, Shireen

“…ObjectiveThis study aims to investigate the relationship between diurnal cortisol patterns, cognition and Alzheimer’s disease (AD) biomarkers in memory clinic…”
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The amount of informal and formal care among non-demented and demented elderly persons-results from a Swedish population-based study by Nordberg, G., von Strauss, E., Kåreholt, I., Johansson, L., Wimo, A.

“…Background Developed countries are experiencing a dramatic increase in the proportion of elderly persons, as well as a progressive aging of the elderly…”
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