Search Results - "Kääriäinen, Leevi"

Phosphatidylinositol 3-Kinase-, Actin-, and Microtubule-Dependent Transport of Semliki Forest Virus Replication Complexes from the Plasma Membrane to Modified Lysosomes by Spuul, Pirjo, Balistreri, Giuseppe, Kääriäinen, Leevi, Ahola, Tero

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Role of the Amphipathic Peptide of Semliki Forest Virus Replicase Protein nsP1 in Membrane Association and Virus Replication by SPUUL, Pirjo, SALONEN, Anne, MERITS, Andres, JOKITALO, Eija, KAARIAINEN, Leevi, AHOLA, Tero

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Enzymatic Defects of the nsP2 Proteins of Semliki Forest Virus Temperature-Sensitive Mutants by BALISTRERI, Giuseppe, CALDENTEY, Javier, LEEVI, Kääriäinen, AHOLA, Tero

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Biogenesis of the Semliki Forest Virus RNA Replication Complex by Kujala, P, Ikaeheimonen, A, Ehsani, N, Vihinen, H, Auvinen, P, Kaeaeriaeinen, L

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Properly Folded Nonstructural Polyprotein Directs the Semliki Forest Virus Replication Complex to the Endosomal Compartment by Salonen, Anne, Vasiljeva, Lidia, Merits, Andres, Magden, Julia, Jokitalo, Eija, Kääriäinen, Leevi

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Virus-Specific mRNA Capping Enzyme Encoded by Hepatitis E Virus by Magden, J, Takeda, N, Li, T, Auvinen, P, Ahola, T, Miyamura, T, Merits, A, Kääriäinen, L

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Characterization of the cysteine protease domain of Semliki Forest virus replicase protein nsP2 by in vitro mutagenesis by Golubtsov, Andrey, Kääriäinen, Leevi, Caldentey, Javier

“…The function of Semliki Forest Virus nsP2 protease was investigated by site-directed mutagenesis. Mutations were introduced in its protease domain, Pro39, and…”
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Reaction in Alphavirus mRNA Capping: Formation of a Covalent Complex of Nonstructural Protein nsP1 with 7-Methyl-GMP by Ahola, Tero, Kääriäinen, Leevi

“…After the start of transcription, the 5' ends of eukaryotic mRNA molecules are modified by the addition of a guanylyl residue to form a cap structure,…”
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Semliki Forest virus mRNA capping enzyme requires association with anionic membrane phospholipids for activity by Ahola, Tero, Lampio, Anja, Auvinen, Petri, Kääriäinen, Leevi

“…The replication complexes of all positive strand RNA viruses of eukaryotes are associated with membranes. In the case of Semliki Forest virus (SFV), the main…”
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Virus-Specific mRNA Capping Enzyme Encoded by Hepatitis E Virus by Magden, Julia, Takeda, Naokazu, Li, Tiancheng, Auvinen, Petri, Ahola, Tero, Miyamura, Tatsuo, Merits, Andres, Kääriäinen, Leevi

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A Single Amino Acid Change in the Nuclear Localization Sequence of the nsP2 Protein Affects the Neurovirulence of Semliki Forest Virus by Fazakerley, John K, Boyd, Amanda, Mikkola, Marja L, Kääriäinen, Leevi

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Identification of Mutations Causing Temperature-Sensitive Defects in Semliki Forest Virus RNA Synthesis by Lulla, Valeria, Merits, Andres, Sarin, Peter, Kääriäinen, Leevi, Keränen, Sirkka, Ahola, Tero

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Intracellular Distribution of Rubella Virus Nonstructural Protein P150 by Kujala, P, Ahola, T, Ehsani, N, Auvinen, P, Vihinen, H, Kääriäinen, L

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Alphavirus Replicase Protein NSP1 Induces Filopodia and Rearrangement of Actin Filaments by Laakkonen, P, Auvinen, P, Kujala, P, Kääriäinen, L

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Proteolytic processing of Semliki Forest virus-specific non-structural polyprotein by nsP2 protease by Merits, Andres, Vasiljeva, Lidia, Ahola, Tero, Kaariainen, Leevi, Auvinen, Petri

“…Program in Cellular Biotechnology, Institute of Biotechnology, Viikki Biocenter, University of Helsinki, PO Box 56, FIN-00014, Helsinki, Finland 1 Author for…”
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Inhibition of the membrane fusion machinery prevents exit from the TGN and proteolytic processing by furin by Band, Arja M., Määttä, Juha, Kääriäinen, Leevi, Kuismanen, Esa

“…The Semliki Forest virus (SFV) glycoprotein precursor p62 is processed to the E2 and E3 during the transport from the trans-Golgi network (TGN) to the cell…”
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The Alphavirus Replicase Protein nsP1 Is Membrane-Associated and Has Affinity to Endocytic Organelles by Peränen, Johan, Laakkonen, Pirjo, Hyvönen, Marko, Kääriäinen, Leevi

“…In alphavirus-infected cells the four virus-specific nonstructural proteins (nsP1 -nsP4) are located on modified endosomes and lysosomes known as type I…”
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Virus‐specific capping of tobacco mosaic virus RNA: methylation of GTP prior to formation of covalent complex p126‐m7GMP by Merits, Andres, Kettunen, Reetta, Mäkinen, Kristiina, Lampio, Anja, Auvinen, Petri, Kääriäinen, Leevi, Ahola, Tero

“…In capping cellular mRNAs, a covalent GMP‐enzyme intermediate leads to formation of G(5′)ppp(5′)N at the 5′ end of the RNA, which is modified by methylation…”
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Inhibitors of virus replication: recent developments and prospects by Magden, Julia, Kääriäinen, Leevi, Ahola, Tero

“…The search for inhibitors of viral replication is dependent on understanding the events taking place at the molecular level during viral infection. All the…”
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Identification of a novel function of the alphavirus capping apparatus. RNA 5'-triphosphatase activity of Nsp2 by Vasiljeva, L, Merits, A, Auvinen, P, Kääriäinen, L

“…Both genomic and subgenomic RNAs of the Alphavirus have m(7)G(5')ppp(5')N (cap0 structure) at their 5' end. Previously it has been shown that…”
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