Search Results - "Kántás, Boglárka"
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The Epigenetics of Neuropathic Pain: A Systematic Update
Published in International journal of molecular sciences (05-12-2023)“…Epigenetics deals with alterations to the gene expression that occur without change in the nucleotide sequence in the DNA. Various covalent modifications of…”
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Journal Article -
2
Anti-Nociceptive Effects of Sphingomyelinase and Methyl-Beta-Cyclodextrin in the Icilin-Induced Mouse Pain Model
Published in International journal of molecular sciences (01-05-2024)“…The thermo- and pain-sensitive Transient Receptor Potential Melastatin 3 and 8 (TRPM3 and TRPM8) ion channels are functionally associated in the lipid rafts of…”
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3
The heptapeptide somatostatin analogue TT-232 exerts analgesic and anti-inflammatory actions via SST4 receptor activation: In silico, in vitro and in vivo evidence in mice
Published in Biochemical pharmacology (01-03-2023)“…[Display omitted] Since the conventional and adjuvant analgesics have limited effectiveness frequently accompanied by serious side effects, development of…”
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4
Novel Drug-Like Somatostatin Receptor 4 Agonists are Potential Analgesics for Neuropathic Pain
Published in International journal of molecular sciences (11-12-2019)“…Somatostatin released from the capsaicin-sensitive sensory nerves mediates analgesic and anti-inflammatory effects via the somatostatin sst receptor without…”
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5
Analgesic Effects of Lipid Raft Disruption by Sphingomyelinase and Myriocin via Transient Receptor Potential Vanilloid 1 and Transient Receptor Potential Ankyrin 1 Ion Channel Modulation
Published in Frontiers in pharmacology (27-01-2021)“…Transient Receptor Potential (TRP) Vanilloid 1 and Ankyrin 1 (TRPV1, TRPA1) cation channels are expressed in nociceptive primary sensory neurons, and…”
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6
Antinociceptive Effects of Lipid Raft Disruptors, a Novel Carboxamido-Steroid and Methyl β-Cyclodextrin, in Mice by Inhibiting Transient Receptor Potential Vanilloid 1 and Ankyrin 1 Channel Activation
Published in Frontiers in physiology (23-09-2020)“…Transient Receptor Potential Vanilloid 1 and Ankyrin 1 (TRPV1, TRPA1) cation channels are expressed in nociceptive primary sensory neurons, and play an…”
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In Silico, In Vitro and In Vivo Pharmacodynamic Characterization of Novel Analgesic Drug Candidate Somatostatin SST4 Receptor Agonists
Published in Frontiers in pharmacology (27-01-2021)“…Background: Somatostatin released from the capsaicin-sensitive sensory nerves mediates analgesic and anti-inflammatory effects via its receptor subtype 4 (SST…”
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8
The heptapeptide somatostatin analogue TT-232 exerts analgesic and anti-inflammatory actions via SST 4 receptor activation: In silico, in vitro and in vivo evidence in mice
Published in Biochemical pharmacology (01-03-2023)“…Since the conventional and adjuvant analgesics have limited effectiveness frequently accompanied by serious side effects, development of novel, potent pain…”
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Journal Article -
9
Új Szomatosztatin 4 Receptor Agonista Vegyületek Hatástani Jellemzése Különböző Fájdalommodellekben
Published 01-01-2022“…Neuropátiás fájdalomA neuropátiás fájdalom a Fájdalom Társaságok Nemzetközi Szövetségének (International Association for the Study of Pain: IASP) meghatározása…”
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Dissertation -
10
In Silico , In Vitro and In Vivo Pharmacodynamic Characterization of Novel Analgesic Drug Candidate Somatostatin SST 4 Receptor Agonists
Published in Frontiers in pharmacology (2020)“…Somatostatin released from the capsaicin-sensitive sensory nerves mediates analgesic and anti-inflammatory effects via its receptor subtype 4 (SST ) without…”
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Journal Article