Search Results - "KÖSER, Claudio U"

Prevalence and genetic profiles of isoniazid resistance in tuberculosis patients: A multicountry analysis of cross-sectional data by Dean, Anna S, Zignol, Matteo, Cabibbe, Andrea Maurizio, Falzon, Dennis, Glaziou, Philippe, Cirillo, Daniela Maria, Köser, Claudio U, Gonzalez-Angulo, Lice Y, Tosas-Auget, Olga, Ismail, Nazir, Tahseen, Sabira, Ama, Maria Cecilia G, Skrahina, Alena, Alikhanova, Natavan, Kamal, S M Mostofa, Floyd, Katherine

“…The surveillance of drug resistance among tuberculosis (TB) patients is central to combatting the global TB epidemic and preventing the spread of antimicrobial…”
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Mycobacterium tuberculosis resistance prediction and lineage classification from genome sequencing: comparison of automated analysis tools by Schleusener, Viola, Köser, Claudio U., Beckert, Patrick, Niemann, Stefan, Feuerriegel, Silke

“…Whole-genome sequencing (WGS) has the potential to accelerate drug-susceptibility testing (DST) to design appropriate regimens for drug-resistant tuberculosis…”
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Routine use of microbial whole genome sequencing in diagnostic and public health microbiology by Köser, Claudio U, Ellington, Matthew J, Cartwright, Edward J P, Gillespie, Stephen H, Brown, Nicholas M, Farrington, Mark, Holden, Matthew T G, Dougan, Gordon, Bentley, Stephen D, Parkhill, Julian, Peacock, Sharon J

“…According to the current diagnostic paradigm for Mycobacterium tuberculosis complex (MTBC), clinical samples (usually sputum) are first analysed using smear…”
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A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis by Miotto, Paolo, Tessema, Belay, Tagliani, Elisa, Chindelevitch, Leonid, Starks, Angela M, Emerson, Claudia, Hanna, Debra, Kim, Peter S, Liwski, Richard, Zignol, Matteo, Gilpin, Christopher, Niemann, Stefan, Denkinger, Claudia M, Fleming, Joy, Warren, Robin M, Crook, Derrick, Posey, James, Gagneux, Sebastien, Hoffner, Sven, Rodrigues, Camilla, Comas, Iñaki, Engelthaler, David M, Murray, Megan, Alland, David, Rigouts, Leen, Lange, Christoph, Dheda, Keertan, Hasan, Rumina, Ranganathan, Uma Devi K, McNerney, Ruth, Ezewudo, Matthew, Cirillo, Daniela M, Schito, Marco, Köser, Claudio U, Rodwell, Timothy C

“…A clear understanding of the genetic basis of antibiotic resistance in is required to accelerate the development of rapid drug susceptibility testing methods…”
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Role of Epistasis in Amikacin, Kanamycin, Bedaquiline, and Clofazimine Resistance in Mycobacterium tuberculosis Complex by Vargas, Jr, Roger, Freschi, Luca, Spitaleri, Andrea, Tahseen, Sabira, Barilar, Ivan, Niemann, Stefan, Miotto, Paolo, Cirillo, Daniela Maria, Köser, Claudio U, Farhat, Maha R

“…Antibiotic resistance among bacterial pathogens poses a major global health threat. Mycobacterium tuberculosis complex (MTBC) is estimated to have the highest…”
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‘Those who cannot remember the past are condemned to repeat it’: Drug-susceptibility testing for bedaquiline and delamanid by Köser, Claudio U., Maurer, Florian P., Kranzer, Katharina

“…•Breakpoints that define susceptibility and resistance to anti-tuberculosis drugs are crucial for optimal treatment.•Breakpoints needs to be based on modern…”
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Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting by Tong, Steven Y C, Holden, Matthew T G, Nickerson, Emma K, Cooper, Ben S, Köser, Claudio U, Cori, Anne, Jombart, Thibaut, Cauchemez, Simon, Fraser, Christophe, Wuthiekanun, Vanaporn, Thaipadungpanit, Janjira, Hongsuwan, Maliwan, Day, Nicholas P, Limmathurotsakul, Direk, Parkhill, Julian, Peacock, Sharon J

“…Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infection. Whole-genome sequencing of MRSA has been used to define phylogeny…”
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What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis by Heyckendorf, Jan, Andres, Sönke, Köser, Claudio U, Olaru, Ioana D, Schön, Thomas, Sturegård, Erik, Beckert, Patrick, Schleusener, Viola, Kohl, Thomas A, Hillemann, Doris, Moradigaravand, Danesh, Parkhill, Julian, Peacock, Sharon J, Niemann, Stefan, Lange, Christoph, Merker, Matthias

“…Rapid and accurate drug susceptibility testing (DST) is essential for the treatment of multi- and extensively drug-resistant tuberculosis (M/XDR-TB). We…”
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Whole-Genome Sequencing for Rapid Susceptibility Testing of M. tuberculosis by Köser, Claudio U, Bryant, Josephine M, Becq, Jennifer, Török, M. Estée, Ellington, Matthew J, Marti-Renom, Marc A, Carmichael, Andrew J, Parkhill, Julian, Smith, Geoffrey P, Peacock, Sharon J

“…As reported here, whole-genome sequencing has the potential to rapidly facilitate the determination of antimicrobial susceptibility, especially for…”
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d-Cycloserine Pharmacokinetics/Pharmacodynamics, Susceptibility, and Dosing Implications in Multidrug-resistant Tuberculosis: A Faustian Deal by Deshpande, Devyani, Alffenaar, Jan-Willem C, Köser, Claudio U, Dheda, Keertan, Chapagain, Moti L, Simbar, Noviana, Schön, Thomas, Sturkenboom, Marieke G G, McIlleron, Helen, Lee, Pooi S, Koeuth, Thearith, Mpagama, Stellah G, Banu, Sayera, Foongladda, Suporn, Ogarkov, Oleg, Pholwat, Suporn, Houpt, Eric R, Heysell, Scott K, Gumbo, Tawanda

“…Abstract Background d-cycloserine is used to treat multidrug-resistant tuberculosis. Its efficacy, contribution in combination therapy, and best clinical dose…”
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Phylogenetic polymorphisms in antibiotic resistance genes of the Mycobacterium tuberculosis complex by Feuerriegel, Silke, Köser, Claudio U, Niemann, Stefan

“…Sequence analysis of known antibiotic resistance genes of the Mycobacterium tuberculosis complex (MTBC) is increasingly being used to infer phenotypic…”
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Loss-of-function mutations in ndh do not confer delamanid, ethionamide, isoniazid, or pretomanid resistance in Mycobacterium tuberculosis by Pandey, Sushil, Vilchèze, Catherine, Werngren, Jim, Bainomugisa, Arnold, Mansjö, Mikael, Groenheit, Ramona, Miotto, Paolo, Cirillo, Daniela M, Coulter, Christopher, Baulard, Alain R, Schön, Thomas, Jacobs, Jr, William R, Djaout, Kamel, Köser, Claudio U

“…Results from clinical strains and knockouts of the H37Rv and CDC1551 laboratory strains demonstrated that ( ) is not a resistance-conferring gene for…”
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The exceptions that prove the rule-a historical view of bedaquiline susceptibility by Miotto, Paolo, Cirillo, Daniela M, Schön, Thomas, Köser, Claudio U

“…In the accompanying study, Nimmo and colleagues estimated the dates of emergence of mutations in mmpR5 (Rv0678), the most important resistance gene to the…”
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Convergent evolution and topologically disruptive polymorphisms among multidrug-resistant tuberculosis in Peru by Grandjean, Louis, Gilman, Robert H, Iwamoto, Tomatada, Köser, Claudio U, Coronel, Jorge, Zimic, Mirko, Török, M Estee, Ayabina, Diepreye, Kendall, Michelle, Fraser, Christophe, Harris, Simon, Parkhill, Julian, Peacock, Sharon J, Moore, David A J, Colijn, Caroline

“…Multidrug-resistant tuberculosis poses a major threat to the success of tuberculosis control programs worldwide. Understanding how drug-resistant tuberculosis…”
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Revised Interpretation of the Hain Lifescience GenoType MTBC To Differentiate Mycobacterium canettii and Members of the Mycobacterium tuberculosis Complex by Loiseau, Chloé, Brites, Daniela, Moser, Irmgard, Coll, Francesc, Pourcel, Christine, Robbe-Austerman, Suelee, Escuyer, Vincent, Musser, Kimberlee A, Peacock, Sharon J, Feuerriegel, Silke, Kohl, Thomas A, Niemann, Stefan, Gagneux, Sebastien, Köser, Claudio U

“…Using 894 phylogenetically diverse genomes of the complex (MTBC), we simulated the ability of the Hain Lifescience GenoType MTBC assay to differentiate the…”
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Refined understanding of the impact of the Mycobacterium tuberculosis complex diversity on the intrinsic susceptibility to pretomanid by Rupasinghe, Praharshinie, Reenaers, Rabab, Vereecken, Jens, Mulders, Wim, Cogneau, Sari, Merker, Matthias, Niemann, Stefan, Vally Omar, Shaheed, Rigouts, Leen, Köser, Claudio U, Decroo, Tom, de Jong, Bouke C

“…Previous work reported unprecedented differences in the intrinsic susceptibility of the complex (MTBC) to pretomanid (Pa) using the Mycobacteria Growth…”
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Rapid Whole-Genome Sequencing for Investigation of a Suspected Tuberculosis Outbreak by Török, M Estée, Reuter, Sandra, Bryant, Josephine, Köser, Claudio U, Stinchcombe, Sian V, Nazareth, Bernadette, Ellington, Matthew J, Bentley, Stephen D, Smith, Geoffrey P, Parkhill, Julian, Peacock, Sharon J

“…OA  Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and Moxifloxacin by Yu, Xia, Wang, Guirong, Chen, Suting, Wei, Guomei, Shang, Yuanyuan, Dong, Lingling, Schön, Thomas, Moradigaravand, Danesh, Parkhill, Julian, Peacock, Sharon J, Köser, Claudio U, Huang, Hairong

“…Antofloxacin (AFX) is a novel fluoroquinolone that has been approved in China for the treatment of infections caused by a variety of bacterial species. We…”
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Role of Alanine Racemase Mutations in Mycobacterium tuberculosis d-Cycloserine Resistance by Nakatani, Yoshio, Opel-Reading, Helen K, Merker, Matthias, Machado, Diana, Andres, Sönke, Kumar, S Siva, Moradigaravand, Danesh, Coll, Francesc, Perdigão, João, Portugal, Isabel, Schön, Thomas, Nair, Dina, Devi, K R Uma, Kohl, Thomas A, Beckert, Patrick, Clark, Taane G, Maphalala, Gugu, Khumalo, Derrick, Diel, Roland, Klaos, Kadri, Aung, Htin Lin, Cook, Gregory M, Parkhill, Julian, Peacock, Sharon J, Swaminathan, Soumya, Viveiros, Miguel, Niemann, Stefan, Krause, Kurt L, Köser, Claudio U

“…A screening of more than 1,500 drug-resistant strains of revealed evolutionary patterns characteristic of positive selection for three alanine racemase (Alr)…”
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Importance of the Genetic Diversity within the Mycobacterium tuberculosis Complex for the Development of Novel Antibiotics and Diagnostic Tests of Drug Resistance by Köser, Claudio U, Feuerriegel, Silke, Summers, David K, Archer, John A C, Niemann, Stefan

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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