Search Results - "KÄRKKÄINEN, I"

Critical role of helix 12 of the vitamin D 3 receptor for the partial agonism of carboxylic ester antagonists 1 1Edited by R. Huber by Väisänen, Sami, Peräkylä, Mikael, Kärkkäinen, Jouni I, Steinmeyer, Andreas, Carlberg, Carsten

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Structural evaluation of the agonistic action of a vitamin D analog with two side chains binding to the nuclear vitamin D receptor by Väisänen, Sami, Peräkylä, Mikael, Kärkkäinen, Jouni I, Uskokovic, Milan R, Carlberg, Carsten

“…The vitamin D receptor (VDR) is one of the endocrine members of the nuclear receptor superfamily and has a characteristic high affinity for its natural ligand…”
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Metalloprotease-Disintegrin (ADAM) Genes Are Widely and Differentially Expressed in the Adult CNS by Kärkkäinen, Iivari, Rybnikova, Elena, Pelto-Huikko, Markku, Huovila, Ari-Pekka J.

“…ADAM family of metalloprotease-disintegrins, including enzymes that process TNF-α and β-amyloid precursor protein, has been indicated in neuronal development,…”
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ADAM9, ADAM10, and ADAM15 mRNA levels in the rat brain after kainic acid-induced status epilepticus by Ortiz, R.M., Kärkkäinen, I., Huovila, A.-P.J., Honkaniemi, J.

“…ADAM metalloprotease-disintegrins mediate cell adhesion, proteolytic processing, and signal transduction. In the present study, the mRNA levels of ADAM9,…”
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Assignment of the ADAM15 gene to human chromosome band 1q21.3 by in situ hybridization by Kärkkäinen, I, Karhu, R, Huovila, A P

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Developmental regulation and neuronal expression of the cellular disintegrin ADAM11 gene in mouse nervous system by Rybnikova, E, Kärkkäinen, I, Pelto-Huikko, M, Huovila, A.-P.J

“…ADAM11 is the prototype member of the predominantly CNS-associated clade of the ADAM metalloprotease-disintegrins that has been implicated in neural adhesion…”
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Outlier detection using k-nearest neighbour graph by Hautamaki, V., Karkkainen, I., Franti, P.

“…We present an outlier detection using indegree number (ODIN) algorithm that utilizes k-nearest neighbour graph. Improvements to existing kNN distance-based…”
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Maximum a Posteriori Adaptation of the Centroid Model for Speaker Verification by Hautamaki, Ville, Karkkainen, Tomi, Krkkinen, Ismo, Saastamoinen, Juhani, Tuononen, Marko, Franti, Pasi

“…Maximum a posteriori adapted Gaussian mixture model (GMM-MAP) is widely used in speaker verification. GMMs have three sets of parameters to be adapted: means,…”
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Developmental regulation and neuronal expression of the cellular disintegrin ADAM11 gene in mouse nervous system by RYBNIKOVA, E, KÄRKKÄINEN, I, PELTO-HUIKKO, M, HUOVILA, A.-P. J

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W12-P-001 Altered ADAM15 exon use in human macrophages in response to ox-LDL treatment by Airla, N., Ortiz, R.M., Kalijärvi, M., Kärkkäinen, I., Huovila, A.J., Lehtimäki, T.

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Random swap EM algorithm for finite mixture models in image segmentation by Qinpei Zhao, Hautamaki, V., Karkkainen, I., Franti, P.

“…The expectation-maximization (EM) algorithm is a popular tool in estimating model parameters, especially mixture models. As the EM algorithm is a hill-climbing…”
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Critical role of helix 12 of the vitamin D(3) receptor for the partial agonism of carboxylic ester antagonists by Väisänen, Sami, Peräkylä, Mikael, Kärkkäinen, Jouni I, Steinmeyer, Andreas, Carlberg, Carsten

“…The carboxy-terminal alpha-helix of a nuclear receptor ligand-binding domain (LBD), helix 12, contains a critical, ligand-modulated interface for the…”
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Dynamic local search for clustering with unknown number of clusters by Karkkainen, I., Franti, P.

“…Dynamic clustering problems can be solved by finding several clustering solutions with different number of clusters, and by choosing the one that minimizes a…”
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The I4U system in NIST 2008 speaker recognition evaluation by Haizhou Li, Bin Ma, Kong-Aik Lee, Hanwu Sun, Donglai Zhu, Khe Chai Sim, Changhuai You, Rong Tong, Karkkainen, I., Chien-Lin Huang, Pervouchine, V., Wu Guo, Yijie Li, Lirong Dai, Nosratighods, M., Tharmarajah, T., Epps, J., Ambikairajah, E., Eng-Siong Chng, Schultz, T., Qin Jin

“…This paper describes the performance of the I4U speaker recognition system in the NIST 2008 Speaker Recognition Evaluation. The system consists of seven…”
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Variable metric for binary vector quantization by Karkkainen I, Franti, P.

“…We present a new method for performing vector quantization of binary vectors. The proposed method varies the distance metric and updates the centroids in an…”
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Harmonic torque suppression by manual voltage injection by Karkkainen, I, Arkkio, A

“…A method of suppressing the harmonic torques of electrical machines is presented. Three different saturated motors are simulated using finite element analysis…”
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Gradual model generator for single-pass clustering by Karkkainen, I., Franti, P.

“…We present an algorithm for generating a mixture model from data set by performing a single pass over the data. The method is applicable when the entire data…”
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