Search Results - "K, Surya"

Integrated CO2 Capture and Conversion to Formate and Methanol: Connecting Two Threads by Kar, Sayan, Goeppert, Alain, Prakash, G. K. Surya

“…Conspectus The capture of CO2 from concentrated emission sources as well as from air represents a process of paramount importance in view of the increasing CO2…”
Get full text

Pirtobrutinib: First Non-covalent Tyrosine Kinase Inhibitor for Treating Relapsed or Refractory Mantle Cell Lymphoma in Adults by De, Surya K

“…Mantle Cell Lymphoma (MCL) is an aggressive subtype of Non-hodgkin's Lymphoma (NHL). Bruton Tyrosine Kinase (BTK) is a non-receptor tyrosine kinase, and is one…”
Get more information

New Pyrrolopyrimidines as LRRK2 Inhibitors for Treating Parkinson's Disease by De, Surya K

“…This patent describes the novel pyrroloppyrimidine compounds as LRRK2 kinase inhibitors. The patent includes the synthesis of compounds, compositions…”
Get more information

Novel Pyrazino[2,3-b] Pyrazines as mTOR Kinase Inhibitors for Treating Cancer and other Diseases by De, Surya K

“…This paper describes the synthesis of some heteroaryl compounds and compositions comprising an effective amount of one or more such compounds and methods for…”
Get more information

Oteseconazole: First Approved Orally Bioavailable and Selective CYP51 Inhibitor for the Treatment of Patients with Recurrent Vulvovaginal Candidiasis by De, Surya K

“…Oteseconazole was approved by the US FDA in April 2022. It is the first approved selective and orally bioavailable CYP51 inhibitor for the treatment of…”
Get more information

Abrocitinib: First Globally Approved Selective Janus Kinase-1 Inhibitor for the Treatment of Atopic Dermatitis by De, Surya K

“…Atopic dermatitis is epidermal hyperplasia, skin barrier dysfunction, and the aberrant activation of immune cells. Janus kinase (JAK) is a family of…”
Get more information

Novel Proline Derivatives for Treating COVID-19 by De, Surya K

“…COVID-19 is a contagious disease. Paxlovid, a combination of Nirmatrelvir and Ritonavir, was granted emergency use authorization by the United States Food and…”
Get more information

Sotorasib: First Approved KRAS Mutation Inhibitor for the Treatment of Non-small Cell Lung Cancer by De, Surya K

Get more information

Homogeneous Hydrogenation of CO2 and CO to Methanol: The Renaissance of Low‐Temperature Catalysis in the Context of the Methanol Economy by Sen, Raktim, Goeppert, Alain, Surya Prakash, G. K.

“…The traditional economy based on carbon‐intensive fuels and materials has led to an exponential rise in anthropogenic CO2 emissions. Outpacing the natural…”
Get full text

Anthropogenic Chemical Carbon Cycle for a Sustainable Future by Olah, George A, Prakash, G. K. Surya, Goeppert, Alain

“…Nature’s photosynthesis uses the sun’s energy with chlorophyll in plants as a catalyst to recycle carbon dioxide and water into new plant life. Only given…”
Get full text

Discovery of Novel Cysteine Protease Inhibitors for the Treatment of Coronavirus (COVID-19) by De, Surya K

“…The application describes compounds, such as compounds of general Formula, with warheads and their use in treating medical diseases or disorders, such as viral…”
Get more information

Recent Discovery of Peptidomimetics for the Treatment of Coronavirus (COVID-19), Human Coronavirus, and Enteroviruses by De, Surya K

“…This patent describes the synthesis of compounds, methods, and compositions for preventing, treating, and/or curing Covid-19, human coronavirus, and…”
Get more information

First Approval of Pacritinib as a Selective Janus Associated Kinase-2 Inhibitor for the Treatment of Patients with Myelofibrosis by De, Surya K

“…Myelofibrosis is one kind of bone marrow blood cancer that gives mainly bone marrow scarring. JAK families include JAK1, JAK2, JAK3, and tyrosine kinase 2…”
Get more information

How epigenome drives chromatin folding and dynamics, insights from efficient coarse-grained models of chromosomes by Ghosh, Surya K, Jost, Daniel

“…The 3D organization of chromosomes is crucial for regulating gene expression and cell function. Many experimental and polymer modeling efforts are dedicated to…”
Get full text

Hydroxide Based Integrated CO2 Capture from Air and Conversion to Methanol by Sen, Raktim, Goeppert, Alain, Kar, Sayan, Prakash, G. K. Surya

“…The first example of an alkali hydroxide-based system for CO2 capture and conversion to methanol has been established. Bicarbonate and formate salts were…”
Get full text

Sustainable treatment of paint industry wastewater: Current techniques and challenges by Nair K, Surya, Manu, Basavaraju, Azhoni, Adani

“…Paint manufacturing industries produce wastewater containing high chemical oxygen demand and turbidity, besides organic matter, suspended solids, and heavy…”
Get full text

Integrative CO2 Capture and Hydrogenation to Methanol with Reusable Catalyst and Amine: Toward a Carbon Neutral Methanol Economy by Kar, Sayan, Sen, Raktim, Goeppert, Alain, Prakash, G. K. Surya

“…Herein we report an efficient and recyclable system for tandem CO2 capture and hydrogenation to methanol. After capture in an aqueous amine solution, CO2 is…”
Get full text

A review on the oxidation stability of biodiesel by Yaakob, Zahira, Narayanan, Binitha N., Padikkaparambil, Silija, Unni K., Surya, Akbar P., Mohammed

“…Biodiesel consists of fatty acid monoalkyl esters and is derived from feedstocks, such as vegetable oils, used cooking oils and animal fats. Biodiesel is…”
Get full text

Novel 1,4-Dihydropyrido[2,3-B]Pyrazine-2,3-Dione Derivatives for Treating Cancer and Other Disorders Associated with KRAS Activity by De, Surya K

“…This application describes the synthesis of new 1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione derivatives and methods of using these compounds as KRAS covalent…”
Get more information

Palladium-Catalyzed meta-C–H Allylation of Arenes: A Unique Combination of a Pyrimidine-Based Template and Hexafluoroisopropanol by Bag, Sukdev, K, Surya, Mondal, Arup, Jayarajan, Ramasamy, Dutta, Uttam, Porey, Sandip, Sunoj, Raghavan B, Maiti, Debabrata

“…Controlling remote selectivity and delivering novel functionalities at distal positions in arenes are an important endeavor in contemporary organic synthesis…”
Get full text