Search Results - "Jyh-Cherng Yu"
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GPER‐induced signaling is essential for the survival of breast cancer stem cells
Published in International journal of cancer (15-03-2020)“…G protein‐coupled estrogen receptor‐1 (GPER), a member of the G protein‐coupled receptor (GPCR) superfamily, mediates estrogen‐induced proliferation of normal…”
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2
Propofol-based total intravenous anesthesia did not improve survival compared to desflurane anesthesia in breast cancer surgery
Published in PloS one (07-11-2019)“…Breast cancer is the most common cancer in women and several perioperative factors may account for tumor recurrence and metastasis. The anesthetic agents…”
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3
Sialylation of vasorin by ST3Gal1 facilitates TGF‐β1‐mediated tumor angiogenesis and progression
Published in International journal of cancer (15-04-2019)“…ST3Gal1 is a key sialyltransferase which adds α2,3‐linked sialic acid to substrates and generates core 1 O‐glycan structure. Upregulation of ST3Gal1 has been…”
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4
A functional variant near XCL1 gene improves breast cancer survival via promoting cancer immunity
Published in International journal of cancer (15-04-2020)“…Most genome‐wide association studies (GWASs) identify genetic variants for breast cancer occurrence. In contrast, few are for recurrence and mortality. We…”
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5
MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer
Published in Breast cancer research and treatment (01-08-2012)“…Tumor recurrence and metastasis result in an unfavorable prognosis for cancer patients. Recent studies have suggested that specific microRNAs (miRNAs) may play…”
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6
Transmembrane and coiled-coil domain family 3 (TMCC3) regulates breast cancer stem cell and AKT activation
Published in Oncogene (22-04-2021)“…Cancer stem cells (CSC) play a pivotal role in cancer metastasis and resistance to therapy. Previously, we compared the phosphoproteomes of breast cancer stem…”
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7
Six novel immunoglobulin genes as biomarkers for better prognosis in triple-negative breast cancer by gene co-expression network analysis
Published in Scientific reports (14-03-2019)“…Gene co-expression network analysis (GCNA) can detect alterations in regulatory activities in case/control comparisons. We propose a framework to detect novel…”
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8
Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy
Published in Proceedings of the National Academy of Sciences - PNAS (23-07-2013)“…The circadian clock gene Period2 (PER2) has been suggested to be a tumor suppressor. However, detailed mechanistic evidence has not been provided to support…”
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9
TET1 Suppresses Cancer Invasion by Activating the Tissue Inhibitors of Metalloproteinases
Published in Cell reports (Cambridge) (27-09-2012)“…Tumor suppressor gene silencing through cytosine methylation contributes to cancer formation. Whether DNA demethylation enzymes counteract this oncogenic…”
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10
The interplay between IGF-1R signaling and Hippo-YAP in breast cancer stem cells
Published in Cell communication and signaling (20-04-2023)“…Both IGF-1R/PI3K/AKT/mTOR and Hippo pathways are crucial for breast cancer stem cells (BCSCs). However, their interplay remains unclear. Four triple negative…”
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11
The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stem/progenitors
Published in Breast cancer research : BCR (12-05-2013)“…Dysregulation of the insulin-like growth factor-1 receptor (IGF-1R)/phosphatidylinositol-3-kinase (PI3K)/Akt pathway was shown to correlate with breast cancer…”
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12
The Risk of Breast Cancer between Western and Mediterranean Dietary Patterns
Published in Nutrients (25-04-2023)“…Breast cancer is a significant public health problem globally and prevention strategies have become of great interest as its incidence rises. Exploring the…”
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13
Increased Cellular Levels of MicroRNA-9 and MicroRNA-221 Correlate with Cancer Stemness and Predict Poor Outcome in Human Breast Cancer
Published in Cellular physiology and biochemistry (01-08-2018)“…Abstract Background /Aims: Recent studies of microRNA (miRNA) involvement in tumorigenesis have indicated the critical role of these non-coding small RNAs in…”
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14
Survival outcomes in elderly Taiwanese women according to breast cancer subtype and lymph node status: A single-center retrospective study
Published in PloS one (30-12-2021)“…This study aimed to determine the rates of overall survival and recurrence-free survival among elderly Taiwanese women (>65 years old) according to breast…”
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15
A Novel Oncogenic Role of Inositol Phosphatase SHIP2 in ER‐Negative Breast Cancer Stem Cells: Involvement of JNK/Vimentin Activation
Published in Stem cells (Dayton, Ohio) (01-08-2014)“…Overexpression of SH2‐containing‐5′‐inositol phosphatase‐2 (SHIP2) correlates with poor survival in breast cancer. However, its role in breast cancer stem…”
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16
Diffuse Allergic Reaction to Patent Blue Dye for Sentinel Node Biopsy in Breast Cancer: A Case Report
Published in Journal of medical sciences (Taipei, Taiwan) (01-06-2024)“…We present the case of a 59-year-old Taiwanese female who is married and retired, and was diagnosed with invasive ductal carcinoma in her right breast at stage…”
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17
B-Myb Induces APOBEC3B Expression Leading to Somatic Mutation in Multiple Cancers
Published in Scientific reports (09-03-2017)“…The key signature of cancer genomes is the accumulation of DNA mutations, the most abundant of which is the cytosine-to-thymine (C-to-T) transition that…”
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18
The Effect of MicroRNA-124 Overexpression on Anti-Tumor Drug Sensitivity
Published in PloS one (26-06-2015)“…MicroRNAs play critical roles in regulating various physiological processes, including growth and development. Previous studies have shown that microRNA-124…”
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19
Glycan microarray of Globo H and related structures for quantitative analysis of breast cancer
Published in Proceedings of the National Academy of Sciences - PNAS (19-08-2008)“…Cancer-associated carbohydrate antigens are often found on the surface of cancer cells. Understanding their roles in cancer progression will lead to the…”
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20
Genetic co-expression networks contribute to creating predictive model and exploring novel biomarkers for the prognosis of breast cancer
Published in Scientific reports (31-03-2021)“…Genetic co-expression network (GCN) analysis augments the understanding of breast cancer (BC). We aimed to propose GCN-based modeling for BC relapse-free…”
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