Search Results - "Jy, Wenche"

Evidence of platelet activation in multiple sclerosis by Sheremata, William A, Jy, Wenche, Horstman, Lawrence L, Ahn, Yeon S, Alexander, J Steven, Minagar, Alireza

“…A fatality in one multiple sclerosis (MS) patient due to acute idiopathic thrombocytopenic purpura (ITP) and a near fatality in another stimulated our interest…”
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Red Cell Microparticles Suppress Hematoma Growth Following Intracerebral Hemorrhage in Chronic Nicotine-Exposed Rats by Rehni, Ashish K, Cho, Sunjoo, Zhang, Zhexuan, Khushal, Priyanka, Raval, Ami P, Koch, Sebastian, Perez-Pinzon, Miguel A, Zhao, Weizhao, Jy, Wenche, Dave, Kunjan R

“…Spontaneous intracerebral hemorrhage (sICH) is a disabling stroke sub-type, and tobacco use is a prominent risk factor for sICH. We showed that chronic…”
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Role of platelets in neuroinflammation: a wide-angle perspective by Horstman, Lawrence L, Jy, Wenche, Ahn, Yeon S, Zivadinov, Robert, Maghzi, Amir H, Etemadifar, Masoud, Steven Alexander, J, Minagar, Alireza

“…This review summarizes recent developments in platelet biology relevant to neuroinflammatory disorders. Multiple sclerosis (MS) is taken as the "Poster Child"…”
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Microparticle size and its relation to composition, functional activity, and clinical significance by Jy, Wenche, Horstman, Lawrence L, Ahn, Yeon S

“…It is emerging that cell-derived microparticles (MP) have multiple functional activities in areas including hemostasis, thrombosis, inflammation, and as…”
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Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis by Jimenez, Joaquin J., Jy, Wenche, Mauro, Lucia M., Soderland, Carl, Horstman, Lawrence L., Ahn, Yeon S.

“…Background: Endothelial cells (EC) shed endothelial microparticles (EMP) in activation and apoptosis. Objectives: We compared the antigenic expression of EMP…”
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Effects of Severe Hypertension on Endothelial and Platelet Microparticles by Preston, Richard A, Jy, Wenche, Jimenez, Joaquin J, Mauro, Lucia M, Horstman, Lawrence L, Valle, Madelyn, Aime, Gerard, Ahn, Yeon S

“…ABSTRACT—The molecular mechanisms by which extreme blood pressure elevation leads to vascular injury are not defined. To explore the hypothesis that activation…”
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Presurgical levels of circulating cell-derived microparticles discriminate between patients with and without transfusion in coronary artery bypass graft surgery by Jy, Wenche, PhD, Gómez-Marín, Orlando, MSc, PhD, Salerno, Tomas A., MD, Panos, Anthony L., MD, Williams, Donald, MD, Horstman, Lawrence L., BS, Ahn, Yeon S., MD

“…Objectives Improved understanding of presurgical risk factors for transfusions will lead to reduction in their number and related complications. The goal of…”
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Pharmacokinetics of Human Red Blood Cell Microparticles Prepared Using High-Pressure Extrusion Method by Jy, Wenche, Rehni, Ashish K, Bidot, Jr, Carlos, Navarro-Quero, Hever, Haase, Conner R, Koch, Sebastian, Ahn, Yeon S, Dave, Kunjan R

“…Red blood cell microparticles (RMPs) is a high potency hemostatic agent, which may serve as a viable therapeutic approach. They generate thrombin and effective…”
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Endothelial microparticles correlate with high-risk angiographic lesions in acute coronary syndromes by Bernal-Mizrachi, Leon, Jy, Wenche, Fierro, Christian, Macdonough, Rick, Velazques, Hermes A., Purow, Joshua, Jimenez, Joaquin J., Horstman, Lawrence L., Ferreira, Alexandre, de Marchena, Eduardo, Ahn, Yeon S.

“…Background: Endothelial Microparticles (EMP) are small fragments of endothelial cell membrane shed during apoptosis or activation. Our group has previously…”
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Endothelial microparticles released in thrombotic thrombocytopenic purpura express von Willebrand factor and markers of endothelial activation by Jimenez, Joaquin J., Jy, Wenche, Mauro, Lucia M., Horstman, Lawrence L., Soderland, Carl, Ahn, Yeon S.

“…It has been suggested that endothelial apoptosis is a primary lesion in the pathogenesis of thrombotic thrombocytopenic purpura (TTP). We tested this…”
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Antiphospholipid antibodies: paradigm in transition by Horstman, Lawrence L, Jy, Wenche, Bidot, Carlos J, Ahn, Yeon S, Kelley, Roger E, Zivadinov, Robert, Maghzi, Amir H, Etemadifar, Masoud, Mousavi, Seyed Ali, Minagar, Alireza

“…This is a critical review of anti-phospholipid antibodies (aPL). Most prior reviews focus on the aPL syndrome (APS), a thrombotic condition often marked by…”
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New horizons in the analysis of circulating cell-derived microparticles by Horstman, Lawrence L., Jy, Wenche, Jimenez, Joaquin J., Bidot, Carlos, Ahn, Yeon S.

“…Analysis of circulating cell-derived microparticles (MP) is becoming more refined and clinically useful. This review, stemming from lectures given at Tokyo…”
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Interferon-β1a reduces plasma CD31+ endothelial microparticles (CD31+EMP) in multiple sclerosis by Sheremata, William, Jy, Wenche, Delgado, Sylvia, Minagar, Alireza, McLarty, Jerry, Ahn, Yeon

“…BACKGROUND: A correlation between plasma CD31+ endothelial microparticles (CD31+EMP) levels and clinical, as well as brain MRI activity, in multiple sclerosis…”
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Clinical and neuroimaging correlates of antiphospholipid antibodies in multiple sclerosis: a preliminary study by Bidot, Carlos J, Horstman, Lawrence L, Jy, Wenche, Jimenez, Joaquin J, Bidot, Jr, Carlos, Ahn, Yeon S, Alexander, J Steven, Gonzalez-Toledo, Eduardo, Kelley, Roger E, Minagar, Alireza

“…The presence of antiphospholipid antibodies (APLA) in multiple sclerosis (MS) patients has been reported frequently but no clear relationship between APLA and…”
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Cell-derived microparticles: a mediator of inflammation in aortic valve stenosis? by Ahn, Yeon S, Jy, Wenche, Horstman, Laurence L, Jimenez, Joaquin J

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Antiphospholipid antibodies in immune thrombocytopenic purpura tend to emerge in exacerbation and decline in remission by Bidot, Carlos J., Jy, Wenche, Horstman, Lawrence L., Ahn, Eugene R., Jimenez, Joaquin J., Yaniz, Miriam, Lander, Gabriela, Ahn, Yeon S.

“…Summary Although the presence of antiphospholipid antibodies (APLA) in immune thrombocytopenic purpura (ITP) has been reported, their clinical significance is…”
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Factor VII/VIIa: a new antigen in the anti‐phospholipid antibody syndrome by Bidot, Carlos J., Jy, Wenche, Horstman, Lawrence L., Huisheng, Huang, Jimenez, Joaquin J., Yaniz, Miriam, Ahn, Yeon S.

“…We investigated antibodies to factor VII/VIIa (FVII/VIIa) and five other common target antigens in 33 patients with a history of anti‐phospholipid syndrome…”
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Platelet activation in Helicobacter pylori-associated idiopathic thrombocytopenic purpura: eradication reduces platelet activation but seldom improves platelet counts by Ahn, Eugene R, Tiede, Maike P, Jy, Wenche, Bidot, Carlos J, Fontana, Vincenzo, Ahn, Yeon S

“…It has been suggested that Helicobacter pylori eradication often increases platelet counts in patients with chronic idiopathic thrombocytopenic purpura (ITP)…”
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Vascular dementia in patients with immune thrombocytopenic purpura by Ahn, Yeon S, Horstman, Lawrence L, Jy, Wenche, Jimenez, Joaquin J, Bowen, Brian

“…Introduction: Platelets have been implicated in memory disorders but this has not been investigated in patients with immune or idiopathic thrombocytopenia…”
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Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multiinfarct dementias by Lee, Y J, Jy, W, Horstman, L L, Janania, J, Reyes, Y, Kelley, R E, Ahn, Y S

“…Platelets release microparticles (PMP) upon activation. Elevated levels of PMP were observed in patients with immune thrombocytopenic purpura (ITP), sometimes…”
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