Search Results - "Juvekar, Aarti"

Design and synthesis of (S)- and (R)-enantiomers of [4-(2-hydroxy-1-phenylethylimino)pent-2-ol]dimethyltin(iv) and 2,2-dimethyl-4-phenyl-1,3,2-oxazastannolidine: in vitro antitumor activity against human tumor cell lines and in vivo assay of (S)-enantiomers by Arjmand, Farukh, Sayeed, Fatima, Parveen, Shazia, Tabassum, Sartaj, Juvekar, Aarti S, Zingde, Surekha M

“…New dimethyltin derived antitumor drug candidates (S)- and (R)-[4-(2-hydroxy-1-phenylethylimino)pent-2-ol]dimethyltin(iv), 1 and (S)- and…”
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Remarkable anti-breast cancer activity of ferrocene tagged multi-functionalized 1,4-dihydropyrimidines by Jadhav, Jagannath, Juvekar, Aarti, Kurane, Rajanikant, Khanapure, Sharanabasappa, Salunkhe, Rajashri, Rashinkar, Gajanan

“…A novel series of ferrocene tagged multi-functionalized 1,4-dihydropyrimidines is synthesized by base catalyzed cyclocondensation between ferrocenyl chalcones…”
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Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing ‘click’ chemistry: DNA-binding affinity and anticancer activity by Kamal, Ahmed, Shankaraiah, N., Devaiah, V., Laxma Reddy, K., Juvekar, Aarti, Sen, Subrata, Kurian, Nisha, Zingde, Surekha

“…1,2,3-Triazole based molecules are useful pharmacophores for several DNA-alkylating and cross-linking agents. A series of A/C8, C/C2 and A/C8- C/C2-linked…”
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Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents by Kamal, Ahmed, Surendranadha Reddy, J., Janaki Ramaiah, M., Dastagiri, D., Vijaya Bharathi, E., Ameruddin Azhar, M., Sultana, Farheen, Pushpavalli, S.N.C.V.L., Pal-Bhadra, Manika, Juvekar, Aarti, Sen, Subrata, Zingde, Surekha

“…A series of 3,5-diaryl-isoxazoline/isoxazole linked pyrrolo[2,1- c][1,4]benzodiazepine (PBD) conjugates were prepared. These conjugates showed potent…”
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Carbohydrate-conjugate heterobimetallic complexes: synthesis, DNA binding studies, artificial nuclease activity and in vitro cytotoxicity by Tabassum, Sartaj, Khan, Rais Ahmad, Arjmand, Farukh, Aziz, Mubashira, Juvekar, Aarti S., Zingde, Surekha M.

“…New carbohydrate-conjugated heterobimetallic complexes [C 32H 62N 10O 8NiSn 2Cl 4]Cl 2 (1) and [C 32H 62N 10O 8CuSn 2Cl 4]Cl 2 ( 2) were synthesized and…”
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Remarkable DNA binding affinity and potential anticancer activity of pyrrolo[2,1- c][1,4]benzodiazepine–naphthalimide conjugates linked through piperazine side-armed alkane spacers by Kamal, Ahmed, Ramu, R., Tekumalla, Venkatesh, Ramesh Khanna, G.B., Barkume, Madan S., Juvekar, Aarti S., Zingde, Surekha M.

“…A series of pyrrolobenzodiazepine–naphthalimide conjugates tethered through a piperazine ring system have been designed, synthesized, and evaluated for their…”
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Synthesis, DNA binding, and cytotoxicity studies of pyrrolo[2,1- c][1,4]benzodiazepine-anthraquinone conjugates by Kamal, Ahmed, Ramu, R., Tekumalla, Venkatesh, Khanna, G.B.Ramesh, Barkume, Madan S., Juvekar, Aarti S., Zingde, Surekha M.

“…A series of pyrrolo[2,1- c][1,4]benzodiazepine-anthraquinone conjugates have been prepared and evaluated for their DNA binding ability as well as anticancer…”
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Phosphonate-linked pyrrolo[2,1- c][1,4]benzodiazepine conjugates: Synthesis, DNA-binding affinity and cytotoxicity by Kamal, Ahmed, Kumar, P. Praveen, Seshadri, B.N., Srinivas, O., Kumar, M. Shiva, Sen, Subrata, Kurian, Nisha, Juvekar, Aarti S., Zingde, Surekha M.

“…Phosphonate linked pyrrolo[2,1- c][1,4]benzodiazepine conjugates were synthesized and displayed significant anticancer activity against selected human cancer…”
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Synthesis and Evaluation of Novel N-Substituted-6-methoxynaphthalene-2-Carboxamides as Potential Chemosensitizing Agents for Cancer by Lokhande, Tushar Narendra, Viswanathan, Chelakara Lakshmann, Juvekar, Aarti Shashikant

“…A novel class of molecules with structure N-[3-(heteroaryl)propyl]-6-methoxynaphthalene-2-carboxamides 8—13 were synthesized by condensing…”
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Design, synthesis and biological evaluation of novel pyrazolochalcones as potential modulators of PI3K/Akt/mTOR pathway and inducers of apoptosis in breast cancer cells by Shaik, Anver Basha, Rao, Garikapati Koteswara, Kumar, G. Bharath, Patel, Nibeditha, Reddy, Vangala Santhosh, Khan, Irfan, Routhu, Sunitha Rani, Kumar, C. Ganesh, Veena, Immadi, Chandra Shekar, Kunta, Barkume, Madan, Jadhav, Shailesh, Juvekar, Aarti, Kode, Jyoti, Pal-Bhadra, Manika, Kamal, Ahmed

“…Cancer has been established as the “Emperor of all maladies”. In recent years, medicinal chemistry has focused on identifying novel anti-cancer compounds;…”
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Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole–pyrrolo[2,1- c][1,4]benzodiazepine conjugates by Kamal, Ahmed, Reddy, K. Srinivasa, Khan, M. Naseer A., Shetti, Rajesh V.C.R.N.C., Ramaiah, M. Janaki, Pushpavalli, S.N.C.V.L., Srinivas, Chatla, Pal-Bhadra, Manika, Chourasia, Mukesh, Sastry, G. Narahari, Juvekar, Aarti, Zingde, Surekha, Barkume, Madan

“…A series of benzothiazole and benzoxazole linked pyrrolobenzodiazepine conjugates attached through different alkane or alkylamide spacers was prepared. Their…”
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Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents by Kamal, Ahmed, Ashwini Kumar, B., Suresh, Paidakula, Juvekar, Aarti, Zingde, Surekha

“…A series of new 4β-carbamoyl epipodophyllotoxin analogues have been synthesized and evaluated for their anticancer activity against eleven cancer cell lines…”
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Quinazolinone linked pyrrolo[2,1- c][1,4]benzodiazepine (PBD) conjugates: Design, synthesis and biological evaluation as potential anticancer agents by Kamal, Ahmed, Vijaya Bharathi, E., Janaki Ramaiah, M., Dastagiri, D., Surendranadha Reddy, J., Viswanath, A., Sultana, Farheen, Pushpavalli, S.N.C.V.L., Pal-Bhadra, Manika, Srivastava, Hemant Kumar, Narahari Sastry, G., Juvekar, Aarti, Sen, Subrata, Zingde, Surekha

“…A series of novel quinazolinone linked pyrrolobenzodiazepine (PBD) conjugates were synthesized. These compounds 4a– f and 5a– f were prepared in good yields by…”
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Synthesis and characterization of glycoconjugate tin(IV) complexes: In vitro DNA binding studies, cytotoxicity, and cell death by Tabassum, Sartaj, Khan, Rais Ahmad, Arjmand, Farukh, Sen, Subrata, Kayal, Jyoti, Juvekar, Aarti S., Zingde, Surekha M.

“…New glycosyl derived ligand and its complexes, with SnCl 4·5H 2O (1) and (CH 3) 2SnCl 2 (2) were synthesized and characterized by spectroscopic (IR, 1H, 13C,…”
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Decreased B16F10 melanoma growth and impaired tumour vascularization in BDF1 mice with quercetin-cyclodextrin binary system by Kale, Rajendrakumar, Saraf, Madhusudan, Juvekar, Aarti, Tayade, Pralhad

“…The aim of this work was to study the inclusion behaviour of a poorly water‐soluble bioflavonoid, quercetin, towards sulfobutyl ether‐7β‐cyclodextrin. It also…”
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Molecular Encapsulation of Thalidomide with Sulfobutyl Ether-7 β-Cyclodextrin for Immediate Release Property: Enhanced In Vivo Antitumor and Antiangiogenesis Efficacy in Mice by Kale, Rajendrakumar, Tayade, Pralhad, Saraf, Madhusudan, Juvekar, Aarti

“…Thalidomide's reported ability to inhibit tumor angiogenesis has led to clinical trials determining its effectiveness in combating various types of cancer…”
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Synthesis, DNA-binding ability and evaluation of antitumour activity of triazolo[1,2,4]benzothiadiazine linked pyrrolo[2,1- c][1,4]benzodiazepine conjugates by Kamal, Ahmed, Khan, M. Naseer A., Srikanth, Y.V.V., Srinivasa Reddy, K., Juvekar, Aarti, Sen, Subrata, Kurian, Nisha, Zingde, Surekha

“…Novel triazolobenzothiadiazine–PBD conjugates were synthesized and exhibited significant anticancer activity against lung, breast, oral, colon, cervix,…”
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Synthesis of carbohydrate-conjugate heterobimetallic CuII–Sn2IV and ZnII–Sn2IV complexes; their interactions with CT DNA and nucleotides; DNA cleavage, in-vitro cytotoxicity by Tabassum, Sartaj, Khan, Rais Ahmad, Arjmand, Farukh, Juvekar, Aarti S., Zingde, Surekha M.

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Synthesis, anticancer activity and mitochondrial mediated apoptosis inducing ability of 2,5-diaryloxadiazole–pyrrolobenzodiazepine conjugates by Kamal, Ahmed, Dastagiri, D., Ramaiah, M. Janaki, Bharathi, E. Vijaya, Reddy, J. Surendranadha, Balakishan, G., Sarma, Pranjal, Pushpavalli, S.N.C.V.L., Pal-Bhadra, Manika, Juvekar, Aarti, Sen, Subrata, Zingde, Surekha

“…New class of 2,5-diaryloxadiazole–pyrrolobenzodiazepine conjugates have been prepared and evaluated for their anticancer activity. Further, some of the…”
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1,2,4-Benzothiadiazine linked pyrrolo[2,1- c][1,4]benzodiazepine conjugates: Synthesis, DNA-binding affinity and cytotoxicity by Kamal, Ahmed, Khan, M. Naseer A., Reddy, K. Srinivasa, Ahmed, S. Kaleem, Kumar, M. Shiva, Juvekar, Aarti, Sen, Subrata, Zingde, Surekha

“…Novel 1,2,4-benzothiadiazine–PBD conjugates were synthesized and displayed significant anticancer activity against selected human cancer cell lines…”
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