Search Results - "Juul, T"

High export of dissolved silica from the Greenland Ice Sheet by Meire, L., Meire, P., Struyf, E., Krawczyk, D. W., Arendt, K. E., Yde, J. C., Juul Pedersen, T., Hopwood, M. J., Rysgaard, S., Meysman, F. J. R.

“…Silica is an essential element for marine life and plays a key role in the biogeochemistry of the ocean. Glacial activity stimulates rock weathering,…”
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Prospective evaluation of transanal irrigation for fecal incontinence and constipation by Juul, T., Christensen, P.

“…Background The aim of the present study was to evaluate the effect of transanal irrigation on bowel function and quality of life in a prospective cohort of…”
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The risk of extra‐colonic, extra‐endometrial cancer in the Lynch syndrome by Watson, Patrice, Vasen, Hans F.A., Mecklin, Jukka‐Pekka, Bernstein, Inge, Aarnio, Markku, Järvinen, Heikki J., Myrhøj, Torben, Sunde, Lone, Wijnen, Juul T., Lynch, Henry T.

“…Persons with the Lynch syndrome (LS) are at high risk for cancer, including cancers of the small bowel, stomach, upper urologic tract (renal pelvis and…”
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Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers by Jansen, Anne Ml, van Wezel, Tom, van den Akker, Brendy Ewm, Ventayol Garcia, Marina, Ruano, Dina, Tops, Carli Mj, Wagner, Anja, Letteboer, Tom Gw, Gómez-García, Encarna B, Devilee, Peter, Wijnen, Juul T, Hes, Frederik J, Morreau, Hans

“…Many suspected Lynch Syndrome (sLS) patients who lack mismatch repair (MMR) germline gene variants and MLH1 or MSH2 hypermethylation are currently explained by…”
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Validation of the English translation of the low anterior resection syndrome score by Juul, T., Battersby, N. J., Christensen, P., Janjua, A. Z., Branagan, G., Laurberg, S., Emmertsen, K. J., Moran, B.

“…Aim Many patients having anterior resection for rectal cancer suffer from severe long‐term bowel dysfunction, known as low anterior resection syndrome (LARS)…”
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Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer by Elsayed, Fadwa A, Kets, C Marleen, Ruano, Dina, van den Akker, Brendy, Mensenkamp, Arjen R, Schrumpf, Melanie, Nielsen, Maartje, Wijnen, Juul T, Tops, Carli M, Ligtenberg, Marjolijn J, Vasen, Hans F A, Hes, Frederik J, Morreau, Hans, van Wezel, Tom

“…Germline variants affecting the exonuclease domains of POLE and POLD1 predispose to multiple colorectal adenomas and/or colorectal cancer (CRC). The aim of…”
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Glacial meltwater and primary production are drivers of strong CO2 uptake in fjord and coastal waters adjacent to the Greenland Ice Sheet by Meire, L, Søgaard, D H, Mortensen, J, Meysman, F J R, Soetaert, K, Arendt, K E, Juul-Pedersen, T, Blicher, M E, Rysgaard, S

“…The Greenland Ice Sheet releases large amounts of freshwater, which strongly influences the physical and chemical properties of the adjacent fjord systems and…”
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The complexity of screening PMS2 in DNA isolated from formalin-fixed paraffin-embedded material by Jansen, Anne M L, Tops, Carli M J, Ruano, Dina, van Eijk, Ronald, Wijnen, Juul T, Ten Broeke, Sanne, Nielsen, Maartje, Hes, Frederik J, van Wezel, Tom, Morreau, Hans

“…Germline variants in the DNA mismatch repair (MMR) gene PMS2 cause 1-14% of all Lynch Syndrome cancers. Correct variant analysis of PMS2 is complex due to the…”
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A genetic variant in telomerase reverse transcriptase (TERT) modifies cancer risk in Lynch syndrome patients harbouring pathogenic MSH2 variants by Wiik, Mariann Unhjem, Evans, Tiffany-Jane, Belhadj, Sami, Bolton, Katherine A., Dymerska, Dagmara, Jagmohan-Changur, Shantie, Capellá, Gabriel, Kurzawski, Grzegorz, Wijnen, Juul T., Valle, Laura, Vasen, Hans F. A., Lubinski, Jan, Scott, Rodney J., Talseth-Palmer, Bente A.

“…Individuals with Lynch syndrome (LS), have an increased risk of developing cancer. Common genetic variants of telomerase reverse transcriptase (TERT) have been…”
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An Updated View on Water Masses on the pan‐West Greenland Continental Shelf and Their Link to Proglacial Fjords by Rysgaard, S., Boone, W., Carlson, D., Sejr, M. K., Bendtsen, J., Juul‐Pedersen, T., Lund, H., Meire, L., Mortensen, J.

“…The accelerated melt of the Greenland Ice Sheet has been linked to a sudden increase in the presence of warm subsurface coastal water in west Greenland. Yet…”
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A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 by Koessler, Thibaud, Chandler, Ian, Buch, Stephan, Agúndez, Jose AG, Caldés, Trinidad, Howarth, Kimberley, Walther, Axel, Ladero, Jose M, Morreau, Hans, Giles, Graham G, Cazier, Jean-Baptiste, Castells, Antoni, Maher, Eamonn R, Wood, Wendy, Försti, Asta, Southey, Melissa C, Broderick, Peter, Hopper, John L, de la Hoya, Miguel, Webb, Emily, Wijnen, Juul T, Aaltonen, Lauri, Dunlop, Malcolm G, John, Ulrich, Fielding, Sarah, Barnetson, Rebecca A, Barclay, Ella, Martin, Lynn, Bishop, D Timothy, Tuupanen, Sari, Tenesa, Albert, Jaeger, Emma, Cheng, K K, Niittymäki, Iina, Karhu, Auli, Schreiber, Stefan, Peto, Julian, Völzke, Henry, Schafmayer, Clemens, Luk, J, Vodicka, Pavel, Vijayakrishnan, Jayaram, Carracedo, Angel, Houlston, Richard S, Tomlinson, Ian PM, Rowan, Andrew, Ruiz-Ponte, Clara, Ho, Judy WC, Kemp, Zoe, Lipton, Lara, Sullivan, Kate, Penegar, Steven, Prendergast, James GD, Carvajal-Carmona, Luis, Hampe, Jochen, Sham, Pak C, Kerr, David, Pharoah, Paul, Severi, Gianluca, Campbell, Harry, Pittman, Alan M, Gray, Richard, Castellví-Bel, Sergi, Spain, Sarah, Domingo, Enric, Hemminki, Kari, Lubbe, Steven, Thomas, Huw, van Wezel, Tom, Naccarati, Alessio, Gorman, Maggie, Lucassen, Anneke, Farrington, Susan M, Qureshi, Mobshra, Evans, D Gareth R

“…To identify colorectal cancer (CRC) susceptibility alleles, we conducted a genome-wide association study. In phase 1, we genotyped 550,163 tagSNPs in 940…”
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Dutch validation of the low anterior resection syndrome score by Hupkens, B. J. P., Breukink, S. O., Olde Reuver of Briel, C., Tanis, P. J., de Noo, M. E., van Duijvendijk, P., van Westreenen, H. L., Dekker, J. W. T., Chen, T. Y. T., Juul, T.

“…Aim The aim of this study was to validate the Dutch translation of the low anterior resection syndrome (LARS) score in a population of Dutch rectal cancer…”
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Distinct Patterns of Somatic Mosaicism in the APC Gene in Neoplasms From Patients With Unexplained Adenomatous Polyposis by Jansen, Anne M.L, Crobach, Stijn, Geurts-Giele, Willemina R.R, van den Akker, Brendy E.W.M, Garcia, Marina Ventayol, Ruano, Dina, Nielsen, Maartje, Tops, Carli M.J, Wijnen, Juul T, Hes, Frederik J, van Wezel, Tom, Dinjens, Winand N.M, Morreau, Hans

“…We investigated the presence and patterns of mosaicism in the APC gene in patients with colon neoplasms not associated with any other genetic variants; we…”
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Multidecadal Water Mass Dynamics on the West Greenland Shelf by Mortensen, J., Rysgaard, S., Winding, M. H. S., Juul‐Pedersen, T., Arendt, K. E., Lund, H., Stuart‐Lee, A. E., Meire, L.

“…The waters on the West Greenland continental shelf and slope play an important role in the global climate system with their link to the subpolar North Atlantic…”
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Insertion of an SVA element, a nonautonomous retrotransposon, in PMS2 intron 7 as a novel cause of lynch syndrome by van der Klift, Heleen M., Tops, Carli M., Hes, Frederik J., Devilee, Peter, Wijnen, Juul T.

“…Heterozygous germline mutations in the mismatch repair gene PMS2 predispose carriers for Lynch syndrome, an autosomal dominant predisposition to cancer. Here,…”
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Validation and Implementation of BRCA1/2 Variant Screening in Ovarian Tumor Tissue by de Jonge, Marthe M., Ruano, Dina, van Eijk, Ronald, van der Stoep, Nienke, Nielsen, Maartje, Wijnen, Juul T., ter Haar, Natalja T., Baalbergen, Astrid, Bos, Monique E.M.M., Kagie, Marjolein J., Vreeswijk, Maaike P.G., Gaarenstroom, Katja N., Kroep, Judith R., Smit, Vincent T.H.B.M., Bosse, Tjalling, van Wezel, Tom, van Asperen, Christi J.

“…BRCA1/2 variant analysis in tumor tissue could streamline the referral of patients with epithelial ovarian, fallopian tube, or primary peritoneal cancer to…”
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Enrichment of Low Penetrance Susceptibility Loci in a Dutch Familial Colorectal Cancer Cohort by MIDDELDORP, Anneke, JAGMOHAN-CHANGUR, Shantie, WIJNEN, Juul T, MORREAU, Hans, VAN WEDEL, Tom, VAN EIJK, Ronald, TOPS, Carli, DEVILEE, Peter, VASEN, Hans F. A, HES, Frederik J, HOULSTON, Richard, TOMLINSON, Ian, HOUWING-DUISTERMAAT, Jeanine J

“…Recent genome-wide association studies have identified several loci that confer an increased risk of colorectal cancer (CRC). We studied the role of the…”
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Comment on 'The TAPE score' by Juul, T., Laurberg, S.

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Spatial and temporal distribution of planktonic protists in the East Greenland fjord and offshore waters by Krawczyk, D. W., Arendt, K. E., Juul-Pedersen, T., Sejr, M. K., Blicher, M. E., Jakobsen, H. H.

“…Summer planktonic protist assemblages (>20 μm) were investigated in the East Greenland Young Sound fjord and offshore waters between 2009 and 2012. Samples…”
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Exome sequencing of germline DNA from non-BRCA1/2 familial breast cancer cases selected on the basis of aCGH tumor profiling by Hilbers, Florentine S, Meijers, Caro M, Laros, Jeroen F J, van Galen, Michiel, Hoogerbrugge, Nicoline, Vasen, Hans F A, Nederlof, Petra M, Wijnen, Juul T, van Asperen, Christi J, Devilee, Peter

“…The bulk of familial breast cancer risk (∼70%) cannot be explained by mutations in the known predisposition genes, primarily BRCA1 and BRCA2. Underlying…”
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