Search Results - "Juul, Sandra E."

Perinatal Iron Deficiency: Implications for Mothers and Infants by Juul, Sandra E, Derman, Richard J, Auerbach, Michael

“…Iron deficiency, with or without anemia, is common in pregnant women. In fact, nearly 30% of reproductive-age women are anemic worldwide, and anemia in…”
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Erythropoietin and Neonatal Neuroprotection by Juul, Sandra E., MD, PhD, Pet, Gillian C., MD, MS

“…Certain groups of neonates are at high risk of developing long-term neurodevelopmental impairment and might be considered candidates for neuroprotective…”
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Erythropoietin: Emerging Role of Erythropoietin in Neonatal Neuroprotection by Rangarajan, Vijayeta, MBChB, Juul, Sandra E., MD, PhD

“…Abstract Background In the last two decades, there has been considerable evolution in understanding the role of erythropoietin in neuroprotection…”
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Iron and Neurodevelopment in Preterm Infants: A Narrative Review by German, Kendell R., Juul, Sandra E.

“…Iron is critical for brain development, playing key roles in synaptogenesis, myelination, energy metabolism and neurotransmitter production. NICU infants are…”
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A working model for hypothermic neuroprotection by Wassink, Guido, Davidson, Joanne O., Lear, Christopher A., Juul, Sandra E., Northington, Frances, Bennet, Laura, Gunn, Alistair J.

“…Therapeutic hypothermia significantly improves survival without disability in near‐term and full‐term newborns with moderate to severe hypoxic–ischaemic…”
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High-Dose Erythropoietin and Hypothermia for Hypoxic-Ischemic Encephalopathy: A Phase II Trial by Wu, Yvonne W, Mathur, Amit M, Chang, Taeun, McKinstry, Robert C, Mulkey, Sarah B, Mayock, Dennis E, Van Meurs, Krisa P, Rogers, Elizabeth E, Gonzalez, Fernando F, Comstock, Bryan A, Juul, Sandra E, Msall, Michael E, Bonifacio, Sonia L, Glass, Hannah C, Massaro, An N, Dong, Lawrence, Tan, Katherine W, Heagerty, Patrick J, Ballard, Roberta A

“…To determine if multiple doses of erythropoietin (Epo) administered with hypothermia improve neuroradiographic and short-term outcomes of newborns with…”
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Pharmacologic Neuroprotective Strategies in Neonatal Brain Injury by Juul, Sandra E., MD, PhD, Ferriero, Donna M., MD, MS

“…This article explains the mechanisms underlying choices of pharmacotherapy for hypoxic-ischemic insults of both preterm and term babies. Some preclinical data…”
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Effects of Transfusions in Extremely Low Birth Weight Infants: A Retrospective Study by Valieva, Olga A., BS, Strandjord, Thomas P., MD, Mayock, Dennis E., MD, Juul, Sandra E., MD, PhD

“…Objectives To determine the risks and benefits associated with the transfusion of packed red blood cells (PRBCs) in extremely low birth weight (ELBW) infants…”
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How well does neonatal neuroimaging correlate with neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy? by Wu, Yvonne W., Monsell, Sarah E., Glass, Hannah C., Wisnowski, Jessica L., Mathur, Amit M., McKinstry, Robert C., Bluml, Stefan, Gonzalez, Fernando F., Comstock, Bryan A., Heagerty, Patrick J., Juul, Sandra E.

“…Background In newborns with hypoxic-ischemic encephalopathy (HIE), the correlation between neonatal neuroimaging and the degree of neurodevelopmental…”
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Erythropoietin for Neuroprotection in Neonatal Encephalopathy: Safety and Pharmacokinetics by WU, Yvonne W, BAUER, Larry A, GONZALEZ, Fernando F, GLASS, Hannah C, JUUL, Sandra E, BALLARD, Roberta A, FERRIERO, Donna M, GLIDDEN, David V, MAYOCK, Dennis E, CHANG, Taeun, DURAND, David J, DONGLI SONG, BONIFACIO, Sonia L

“…To determine the safety and pharmacokinetics of erythropoietin (Epo) given in conjunction with hypothermia for hypoxic-ischemic encephalopathy (HIE). We…”
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Neonatal Anemia by German, Kendell R, Juul, Sandra E

“…All neonates experience a downtrend in their hematocrit values immediately following the birth through normal falls in erythropoietin (Epo) production,…”
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Which Neuroprotective Agents are Ready for Bench to Bedside Translation in the Newborn Infant? by Robertson, Nicola J., MB ChB, PhD, Tan, Sidhartha, MD, Groenendaal, Floris, MD, PhD, van Bel, Frank, MD, PhD, Juul, Sandra E., MD, PhD, Bennet, Laura, PhD, Derrick, Matthew, MD, Back, Stephen A., MD, PhD, Chavez Valdez, Raul, MD, Northington, Frances, MD, Gunn, Alistair Jan, MB ChB, PhD, Mallard, Carina, PhD

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Maternal Nutritional Status and the Microbiome across the Pregnancy and the Post-Partum Period by Strobel, Katie M, Juul, Sandra E, Hendrixson, David Taylor

“…Appropriate nutrition during pregnancy and the post-partum period is vital for both the mothers and their offspring. Both under- and over-nourished status may…”
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Whole genome methylation and transcriptome analyses to identify risk for cerebral palsy (CP) in extremely low gestational age neonates (ELGAN) by Massaro, An N., Bammler, Theo K., MacDonald, James W., Perez, Krystle M., Comstock, Bryan, Juul, Sandra E.

“…Preterm birth remains the leading identifiable risk factor for cerebral palsy (CP), a devastating form of motor impairment due to developmental brain injury…”
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The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury by McAdams, Ryan M., Juul, Sandra E.

“…Perinatal brain injury frequently complicates preterm birth and leads to significant long-term morbidity. Cytokines and inflammatory cells are mediators in the…”
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Evaluating Neuroprotective Effects of Uridine, Erythropoietin, and Therapeutic Hypothermia in a Ferret Model of Inflammation-Sensitized Hypoxic-Ischemic Encephalopathy by Corry, Kylie A, White, Olivia R, Shearlock, AnnaMarie E, Moralejo, Daniel H, Law, Janessa B, Snyder, Jessica M, Juul, Sandra E, Wood, Thomas R

“…Perinatal hypoxic-ischemic (HI) brain injury, often in conjunction with an inflammatory insult, is the most common cause of death or disability in neonates…”
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Erythropoietin and Hypothermia for Hypoxic-Ischemic Encephalopathy by Rogers, Elizabeth E., MD, Bonifacio, Sonia L., MD, Glass, Hannah C., MDCM, Juul, Sandra E., MD, Chang, Taeun, MD, Mayock, Dennis E., MD, Durand, David J., MD, Song, Dongli, MD, Barkovich, Anthony J., MD, Ballard, Roberta A., MD, Wu, Yvonne W., MD, MPH

“…Abstract Background Erythropoietin is neuroprotective in animal models of neonatal hypoxic-ischemic encephalopathy. We previously reported a phase I safety and…”
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Erythropoietin and Brain Magnetic Resonance Imaging Findings in Hypoxic-Ischemic Encephalopathy: Volume of Acute Brain Injury and 1-Year Neurodevelopmental Outcome by Mulkey, Sarah B., MD, PhD, Ramakrishnaiah, Raghu H., MBBS, McKinstry, Robert C., MD, PhD, Chang, Taeun, MD, Mathur, Amit M., MD, Mayock, Dennis E., MD, Van Meurs, Krisa P., MD, Schaefer, G. Bradley, MD, Luo, Chunqiao, MS, Bai, Shasha, PhD, Juul, Sandra E., MD, PhD, Wu, Yvonne W., MD, MPH

“…In the Neonatal Erythropoietin and Therapeutic Hypothermia Outcomes study, 9/20 erythropoietin-treated vs 12/24 placebo-treated infants with hypoxic-ischemic…”
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A More Comprehensive Approach to the Neuroprotective Potential of Long-Chain Polyunsaturated Fatty Acids in Preterm Infants Is Needed-Should We Consider Maternal Diet and the n-6:n-3 Fatty Acid Ratio? by Klevebro, Susanna, Juul, Sandra E, Wood, Thomas R

“…There is growing evidence that long-chain polyunsaturated fatty acids (LCPUFAs) are of importance for normal brain development. Adequate supply of LCPUFAs may…”
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Erythropoietin as a neuroprotectant for neonatal brain injury: animal models by Traudt, Christopher M, Juul, Sandra E

“…Prematurity and perinatal hypoxia-ischemia are common problems that result in significant neurodevelopmental morbidity and high mortality worldwide. The…”
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