Search Results - "Justine Lequesne"

vsgoftest : An R Package for Goodness-of-Fit Testing Based on Kullback-Leibler Divergence by Lequesne, Justine, Regnault, Philippe

“…The R package vsgoftest performs goodness-of-fit (GOF) tests, based on Shannon entropy and Kullback-Leibler divergence, developed by Vasicek (1976) and Song…”
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Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol by Lesueur, Paul, Lequesne, Justine, Grellard, Jean-Michel, Dugué, Audrey, Coquan, Elodie, Brachet, Pierre-Emmanuel, Geffrelot, Julien, Kao, William, Emery, Evelyne, Berro, David Hassanein, Castera, Laurent, Goardon, Nicolas, Lacroix, Joëlle, Lange, Marie, Capel, Aurélie, Leconte, Alexandra, Andre, Benoit, Léger, Angélique, Lelaidier, Anaïs, Clarisse, Bénédicte, Stefan, Dinu

“…Despite multimodality treatments including neurosurgery, radiotherapy and chemotherapy, glioblastoma (GBM) prognosis remains poor. GBM is classically…”
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Circulating PIK3CA mutation detection at diagnosis in non-metastatic inflammatory breast cancer patients by Allouchery, Violette, Perdrix, Anne, Calbrix, Céline, Berghian, Anca, Lequesne, Justine, Fontanilles, Maxime, Leheurteur, Marianne, Etancelin, Pascaline, Sarafan-Vasseur, Nasrin, Di Fiore, Frédéric, Clatot, Florian

“…Inflammatory breast cancer (IBC) is an aggressive BC subtype with poor outcomes. A targetable somatic PIK3CA mutation is reported in 30% of IBC, allowing for…”
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Targeted genotyping of circulating tumor DNA for classical Hodgkin lymphoma monitoring: a prospective study by Camus, Vincent, Viennot, Mathieu, Lequesne, Justine, Viailly, Pierre-Julien, Bohers, Elodie, Bessi, Lucile, Marcq, Bénédicte, Etancelin, Pascaline, Dubois, Sydney, Picquenot, Jean-Michel, Veresezan, Elena-Liana, Cornic, Marie, Burel, Lucie, Loret, Justine, Becker, Stéphanie, Decazes, Pierre, Lenain, Pascal, Lepretre, Stéphane, Lemasle, Emilie, Lanic, Hélène, Ménard, Anne-Lise, Contentin, Nathalie, Tilly, Hervé, Stamatoullas, Aspasia, Jardin, Fabrice

“…The relevance of circulating tumor DNA (ctDNA) analysis as a liquid biopsy and minimal residual disease tool in the management of classical Hodgkin Lymphoma…”
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Inflammation at diagnosis and cognitive impairment two years later in breast cancer patients from the Canto-Cog study by Duivon, Mylène, Lequesne, Justine, Di Meglio, Antonio, Pradon, Caroline, Vaz-Luis, Ines, Martin, Anne-Laure, Everhard, Sibille, Broutin, Sophie, Rigal, Olivier, Bousrih, Chayma, Lévy, Christelle, Lerebours, Florence, Lange, Marie, Joly, Florence

“…Inflammation could be related to cancer-related cognitive impairment (CRCI) and might be used as a predictive marker of long-term CRCI. We evaluated…”
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Potential of PSMA for breast cancer in nuclear medicine: digital quantitative immunohistochemical analysis and implications for a theranostic approach by Neviere, Zoé, Blanc-Fournier, Cécile, Guizard, Anne-Valérie, Elie, Nicolas, Giffard, Florence, Lequesne, Justine, Emile, George, Poulain, Laurent, Lasnon, Charline

“…Further research is still needed to fully understand the potential of prostate-specific membrane antigen (PSMA) in breast cancer (BC) and to develop and…”
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A randomised study to evaluate the potential added value of shared meditation involving people with cancer, health professionals and third persons compared to meditation conducted with patients only: design of the Implic-2 protocol by Prevost, Virginie, Tran, Titi, Leconte, Alexandra, Lequesne, Justine, Fernette, Marie, Segura, Carine, Chevigné, Sylvie, Gouriot, Mylène, Clarisse, Bénédicte

“…In oncology, the suffering of patients and the burnout of health professionals are key issues. Mindfulness meditation is a holistic approach that can help to…”
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TALASUR trial: a single arm phase II trial assessing efficacy and safety of TALazoparib and Avelumab as maintenance therapy in platinum-Sensitive metastatic or locally advanced URothelial carcinoma by Coquan, Elodie, Clarisse, Bénédicte, Lequesne, Justine, Brachet, Pierre-Emmanuel, Nevière, Zoé, Meriaux, Emeline, Bonnet, Isabelle, Castera, Marie, Goardon, Nicolas, Boutrois, Jeremy, Travers, Romain, Joly, Florence, Grellard, Jean-Michel, Thiery-Vuillemin, Antoine

“…Urothelial carcinoma (UC) is the ninth most commonly diagnosed cancer worldwide, with a 3.8/1 male to female ratio. Platinum-based chemotherapy is the first…”
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Exploration of effects of galvanic vestibular stimulation on circadian rhythms and its associations with sleep and spatial memory in patients with breast cancer: The ICANSLEEP-2 protocol by Galin, Melvin, de Girolamo, Laura, Clarisse, Bénédicte, Segura-Djezzar, Carine, Glöckner, Franka, Elia, Clara, Réhel, Stéphane, Clochon, Patrice, Doidy, Franck, Chavant, Julien, Etard, Olivier, Viader, Fausto, Grellard, Jean-Michel, Lequesne, Justine, Joly, Florence, Eustache, Francis, Martin, Tristan, Giffard, Bénédicte, Quarck, Gaëlle, Perrier, Joy

“…Patients with breast cancer (BC) exhibit circadian rhythm disruptions, mainly of rest-activity rhythm (RAR), of which sleep is an essential component, and…”
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Risk of early progression according to circulating ESR1 mutation, CA-15.3 and cfDNA increases under first-line anti-aromatase treatment in metastatic breast cancer by Clatot, Florian, Perdrix, Anne, Beaussire, Ludivine, Lequesne, Justine, Lévy, Christelle, Emile, George, Bubenheim, Michael, Lacaille, Sigrid, Calbrix, Céline, Augusto, Laetitia, Guillemet, Cécile, Alexandru, Cristina, Fontanilles, Maxime, Sefrioui, David, Burel, Lucie, Guénot, Sabine, Richard, Doriane, Sarafan-Vasseur, Nasrin, Di Fiore, Frédéric

“…Endocrine therapy is recommended as a first-line treatment for hormone receptor-positive metastatic breast cancer (HR+MBC) patients. No biomarker has been…”
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Cognitive assessment in patients treated by immunotherapy: the prospective Cog-Immuno trial by Lange, Marie, Clarisse, Bénédicte, Leconte, Alexandra, Dembélé, Kléouforo-Paul, Lequesne, Justine, Nicola, Celeste, Dubois, Martine, Derues, Laurence, Gidron, Yori, Castel, Hélène, Joly, Florence

“…The discovery of the importance of the immune system and its role in oncogenesis led to the development of immunotherapy, a treatment that represents a major…”
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Perioperative treatment in resectable gastric cancer with spartalizumab in combination with fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT): a phase II study (GASPAR) by Dos Santos, Mélanie, Lequesne, Justine, Leconte, Alexandra, Corbinais, Stéphane, Parzy, Aurélie, Guilloit, Jean-Marc, Varatharajah, Sharmini, Brachet, Pierre-Emmanuel, Dorbeau, Marine, Vaur, Dominique, Weiswald, Louis-Bastien, Poulain, Laurent, Le Gallic, Corentin, Castera-Tellier, Marie, Galais, Marie-Pierre, Clarisse, Bénédicte

“…Perioperative chemotherapy and surgery are a standard of care for patients with resectable gastric or gastroesophageal junction (GEJ) adenocarcinoma. However,…”
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Impact of Taxanes, Endocrine Therapy, and Deleterious Germline BRCA Mutations on Anti-müllerian Hormone Levels in Early Breast Cancer Patients Treated With Anthracycline- and Cyclophosphamide-Based Chemotherapy by Lambertini, Matteo, Olympios, Nathalie, Lequesne, Justine, Calbrix, Céline, Fontanilles, Maxime, Loeb, Agnès, Leheurteur, Marianne, Demeestere, Isabelle, Di Fiore, Frédéric, Perdrix, Anne, Clatot, Florian

“…Limited evidence exists on the impact of adding a taxane, using endocrine therapy and carrying a deleterious germline mutation on ovarian reserve measured by…”
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HELENA: HER2-Low as a prEdictive factor of response to Neoadjuvant chemotherapy in eArly breast cancer by Cherifi, François, Da Silva, Angélique, Johnson, Alison, Blanc-Fournier, Cécile, Abramovici, Olivia, Broyelle, Antonin, Levy, Christelle, Allouache, Djelila, Hrab, Ioana, Segura, Carine, Morel, Adeline, Villemin, Maud, Boscher, Clémence, Dubot-Poitelon, Coraline, Rottier, Pauline, Lequesne, Justine, Emile, George

“…HER2 expression has a prognostic and predictive impact in early-stage breast cancer (BC). HER2 positive BC (immunohistochemistry (IHC) score 3 + or 2 + with in…”
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Diagnostic and prognostic value of a 7-panel mutation testing in thyroid nodules with indeterminate cytology: the SWEETMAC study by Bardet, Stéphane, Goardon, Nicolas, Lequesne, Justine, Vaur, Dominique, Ciappuccini, Renaud, Leconte, Alexandra, Monpeyssen, Hervé, Saguet-Rysanek, Virginie, Clarisse, Bénédicte, Lasne-Cardon, Audrey, Ménégaux, Fabrice, Leenhardt, Laurence, Buffet, Camille

“…Purpose The aim of this prospective study (ClinicalTrials.gov: NCT01880203) was to evaluate the diagnostic and prognostic value of a 7-panel mutation testing…”
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ORGAVADS: establishment of tumor organoids from head and neck squamous cell carcinoma to assess their response to innovative therapies by Perréard, Marion, Florent, Romane, Divoux, Jordane, Grellard, Jean-Michel, Lequesne, Justine, Briand, Mélanie, Clarisse, Bénédicte, Rousseau, Nathalie, Lebreton, Esther, Dubois, Brice, Harter, Valentin, Lasne-Cardon, Audrey, Drouet, Julien, Johnson, Alisson, Le Page, Anne-Laure, Bazille, Céline, Jeanne, Corinne, Figeac, Martin, Goardon, Nicolas, Vaur, Dominique, Micault, Emmanuel, Humbert, Maxime, Thariat, Juliette, Babin, Emmanuel, Poulain, Laurent, Weiswald, Louis-Bastien, Bastit, Vianney

“…Radiotherapy is one of the cornerstones of the treatment of Head and Neck Squamous Cell Carcinomas (HNSCC). However, radioresistance is associated with a high…”
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Effects of sleep disturbances and circadian rhythms modifications on cognition in breast cancer women before and after adjuvant chemotherapy: the ICANSLEEP-1 protocol by Elia, Clara, de Girolamo, Laura, Clarisse, Bénédicte, Galin, Melvin, Rehel, Stéphane, Clochon, Patrice, Doidy, Franck, Segobin, Shailendra, Viader, Fausto, Naveau, Mikaël, Delcroix, Nicolas, Segura-Djezzar, Carine, Grellard, Jean-Michel, Lequesne, Justine, Etard, Olivier, Martin, Tristan, Quarck, Gaëlle, Eustache, Francis, Joly, Florence, Giffard, Bénédicte, Perrier, Joy

“…Many patients treated for breast cancer (BC) complain about cognitive difficulties affecting their daily lives. Recently, sleep disturbances and circadian…”
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The impact of introducing deep learning based [18F]FDG PET denoising on EORTC and PERCIST therapeutic response assessments in digital PET/CT by Weyts, Kathleen, Lequesne, Justine, Johnson, Alison, Curcio, Hubert, Parzy, Aurélie, Coquan, Elodie, Lasnon, Charline

“…Background [ 18 F]FDG PET denoising by SubtlePET™ using deep learning artificial intelligence (AI) was previously found to induce slight modifications in…”
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The TRIPLEX study: use of patient-derived tumor organoids as an innovative tool for precision medicine in triple-negative breast cancer by Divoux, Jordane, Florent, Romane, Jacobs, Margaux, Lequesne, Justine, Grellard, Jean-Michel, San, Chankannira, Grossi, Sara, Kerdja, Katia, Clarisse, Bénédicte, Boudier, Gwenaelle, Cherifi, François, Briand, Mélanie, Dolivet, Enora, Johnson, Alisson, Dubois, Brice, Harter, Valentin, Lacroix, Joëlle, Raboutet, Charlotte, Marie, Brigitte, Rousseau, Nathalie, Blanc-Fournier, Cécile, Vaur, Dominique, Figeac, Martin, Poulain, Laurent, Weiswald, Louis-Bastien, Emile, George

“…Background Triple negative breast cancers (TNBC) account for approximately 15% of all breast cancers and are associated with a shorter median survival mainly…”
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CABOCOL-01 trial: a single-arm phase II study assessing safety and efficacy of Cabozantinib for advanced or metastatic cervical carcinoma after platinum treatment failure by Coquan, Elodie, Brachet, Pierre-Emmanuel, Licaj, Idlir, Leconte, Alexandra, Castera, Marie, Lequesne, Justine, Meriaux, Emeline, Bonnet, Isabelle, Lelaidier, Anais, Clarisse, Bénédicte, Joly, Florence

“…Cervical cancer is the tenth diagnosed cancer in the world. Early-stage and locally recurrent disease may be cured with radical surgery or chemo-radiotherapy…”
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