Search Results - "Justin Lee, C."

Optimization of primer sets and detection protocols for SARS-CoV-2 of coronavirus disease 2019 (COVID-19) using PCR and real-time PCR by Park, Myungsun, Won, Joungha, Choi, Byung Yoon, Lee, C. Justin

“…SARS-CoV-2 is very contagious and has rapidly spread globally. Due to various symptomatic and asymptomatic cases and the possibility of asymptomatic…”
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Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2− production by Chun, Heejung, Im, Hyeonjoo, Kang, You Jung, Kim, Yunha, Shin, Jin Hee, Won, Woojin, Lim, Jiwoon, Ju, Yeonha, Park, Yongmin Mason, Kim, Sunpil, Lee, Seung Eun, Lee, Jaekwang, Woo, Junsung, Hwang, Yujin, Cho, Hyesun, Jo, Seonmi, Park, Jong-Hyun, Kim, Daesoo, Kim, Doo Yeon, Seo, Jeong-Sun, Gwag, Byoung Joo, Kim, Young Soo, Park, Ki Duk, Kaang, Bong-Kiun, Cho, Hansang, Ryu, Hoon, Lee, C. Justin

“…Although the pathological contributions of reactive astrocytes have been implicated in Alzheimer’s disease (AD), their in vivo functions remain elusive due to…”
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Multifunctional multi-shank neural probe for investigating and modulating long-range neural circuits in vivo by Shin, Hyogeun, Son, Yoojin, Chae, Uikyu, Kim, Jeongyeon, Choi, Nakwon, Lee, Hyunjoo J., Woo, Jiwan, Cho, Yakdol, Yang, Soo Hyun, Lee, C. Justin, Cho, Il-Joo

“…Investigation and modulation of neural circuits in vivo at the cellular level are very important for studying functional connectivity in a brain. Recently,…”
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British athletics muscle injury classification: a new grading system by Pollock, Noel, James, Steven L J, Lee, Justin C, Chakraverty, Robin

“…The commonly used muscle injury grading systems based on three grades of injury, representing minor, moderate and complete injuries to the muscle, are lacking…”
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Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion by Kim, Tai Young, Jeon, Sangeun, Jang, Youngho, Gotina, Lizaveta, Won, Joungha, Ju, Yeon Ha, Kim, Sunpil, Jang, Minwoo Wendy, Won, Woojin, Park, Mingu Gordon, Pae, Ae Nim, Han, Sunkyu, Kim, Seungtaek, Lee, C. Justin

“…An ongoing pandemic of coronavirus disease 2019 (COVID-19) is now the greatest threat to global public health. Herbal medicines and their derived natural…”
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Transmembrane proteins with unknown function (TMEMs) as ion channels: electrophysiological properties, structure, and pathophysiological roles by Kang, Hyunji, Lee, C. Justin

“…A transmembrane (TMEM) protein with an unknown function is a type of membrane-spanning protein expressed in the plasma membrane or the membranes of…”
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Ultrasonic Neuromodulation via Astrocytic TRPA1 by Oh, Soo-Jin, Lee, Jung Moo, Kim, Hyun-Bum, Lee, Jungpyo, Han, Sungmin, Bae, Jin Young, Hong, Gyu-Sang, Koh, Wuhyun, Kwon, Jea, Hwang, Eun-Sang, Woo, Dong Ho, Youn, Inchan, Cho, Il-Joo, Bae, Yong Chul, Lee, Sungon, Shim, Jae Wan, Park, Ji-Ho, Lee, C. Justin

“…Low-intensity, low-frequency ultrasound (LILFU) is the next-generation, non-invasive brain stimulation technology for treating various neurological and…”
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Control of motor coordination by astrocytic tonic GABA release through modulation of excitation/inhibition balance in cerebellum by Woo, Junsung, Min, Joo Ok, Kang, Dae-Si, Kim, Yoo Sung, Jung, Guk Hwa, Park, Hyun Jung, Kim, Sunpil, An, Heeyoung, Kwon, Jea, Kim, Jeongyeon, Shim, Insop, Kim, Hyung-Gun, Lee, C. Justin, Yoon, Bo-Eun

“…Tonic inhibition in the brain is mediated through an activation of extrasynaptic GABAA receptors by the tonically released GABA, resulting in a persistent…”
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In vivo optical modulation of neural signals using monolithically integrated two-dimensional neural probe arrays by Son, Yoojin, Jenny Lee, Hyunjoo, Kim, Jeongyeon, Shin, Hyogeun, Choi, Nakwon, Justin Lee, C., Yoon, Eui-Sung, Yoon, Euisik, Wise, Kensall D., Geun Kim, Tae, Cho, Il-Joo

“…Integration of stimulation modalities ( e.g. electrical, optical and chemical) on a large array of neural probes can enable an investigation of important…”
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New Insights on Astrocyte Ion Channels: Critical for Homeostasis and Neuron-Glia Signaling by Olsen, Michelle L, Khakh, Baljit S, Skatchkov, Serguei N, Zhou, Min, Lee, C Justin, Rouach, Nathalie

“…Initial biophysical studies on glial cells nearly 50 years ago identified these cells as being electrically silent. These first studies also demonstrated a…”
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Trifluoperazine, a Well-Known Antipsychotic, Inhibits Glioblastoma Invasion by Binding to Calmodulin and Disinhibiting Calcium Release Channel IP3R by Kang, Seokmin, Hong, Jinpyo, Lee, Jung Moo, Moon, Hyo Eun, Jeon, Borami, Choi, Jungil, Yoon, Nal Ae, Paek, Sun Ha, Roh, Eun Joo, Lee, C Justin, Kang, Sang Soo

“…Calcium (Ca ) signaling is an important signaling process, implicated in cancer cell proliferation and motility of the deadly glioblastomas that aggressively…”
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Excitation-Inhibition Imbalance Leads to Alteration of Neuronal Coherence and Neurovascular Coupling under Acute Stress by Han, Kayoung, Lee, Myunghee, Lim, Hyun-Kyoung, Jang, Minwoo Wendy, Kwon, Jea, Lee, C Justin, Kim, Seong-Gi, Suh, Minah

“…A single stressful event can cause morphologic and functional changes in neurons and even malfunction of vascular systems, which can lead to acute stress…”
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Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network by Kim, So Hyun, Im, Sun-Kyoung, Oh, Soo-Jin, Jeong, Sohyeon, Yoon, Eui-Sung, Lee, C. Justin, Choi, Nakwon, Hur, Eun-Mi

“…In native tissues, cellular and acellular components are anisotropically organized and often aligned in specific directions, providing structural and…”
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Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state by Bhalla, Mridula, Lee, C Justin

“…Alzheimer's disease (AD) is characterized by the loss of memory due to aggregation of misphosphorylated tau and amyloid beta (Aβ) plaques in the brain,…”
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Channel-Mediated Tonic GABA Release from Glia by Lee, Soojung, Yoon, Bo-Eun, Berglund, Ken, Oh, Soo-Jin, Park, Hyungju, Shin, Hee-Sup, Augustine, George J, Lee, C. Justin

“…Synaptic inhibition is based on both tonic and phasic release of the inhibitory transmitter γ-aminobutyric acid (GABA). Although phasic GABA release arises…”
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MRI findings and return to play in football: a prospective analysis of 255 hamstring injuries in the UEFA Elite Club Injury Study by Ekstrand, Jan, Lee, Justin C, Healy, Jeremiah C

“…The present study evaluated whether the MRI parameters of hamstring injuries in male professional football players correlate with time to return to play (RTP)…”
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GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease by Jo, Seonmi, Yarishkin, Oleg, Hwang, Yu Jin, Chun, Ye Eun, Park, Mijeong, Woo, Dong Ho, Bae, Jin Young, Kim, Taekeun, Lee, Jaekwang, Chun, Heejung, Park, Hyun Jung, Lee, Da Yong, Hong, Jinpyo, Kim, Hye Yun, Oh, Soo-Jin, Park, Seung Ju, Lee, Hyo, Yoon, Bo-Eun, Kim, YoungSoo, Jeong, Yong, Shim, Insop, Bae, Yong Chul, Cho, Jeiwon, Kowall, Neil W, Ryu, Hoon, Hwang, Eunmi, Kim, Daesoo, Lee, C Justin

“…In Alzheimer's disease, increased MAOB activity in reactive astrocytes leads to enhanced GABA release, and blockage of this pathway ameliorates memory…”
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TREK-1 and Best1 Channels Mediate Fast and Slow Glutamate Release in Astrocytes upon GPCR Activation by Woo, Dong Ho, Han, Kyung-Seok, Shim, Jae Wan, Yoon, Bo-Eun, Kim, Eunju, Bae, Jin Young, Oh, Soo-Jin, Hwang, Eun Mi, Marmorstein, Alan D, Bae, Yong Chul, Park, Jae-Yong, Lee, C. Justin

“…Astrocytes release glutamate upon activation of various GPCRs to exert important roles in synaptic functions. However, the molecular mechanism of release has…”
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Redefining differential roles of MAO-A in dopamine degradation and MAO-B in tonic GABA synthesis by Cho, Hyun-U, Kim, Sunpil, Sim, Jeongeun, Yang, Seulkee, An, Heeyoung, Nam, Min-Ho, Jang, Dong-Pyo, Lee, C. Justin

“…Monoamine oxidase (MAO) is believed to mediate the degradation of monoamine neurotransmitters, including dopamine, in the brain. Between the two types of MAO,…”
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Revisiting the Role of Astrocytic MAOB in Parkinson's Disease by Nam, Min-Ho, Sa, Moonsun, Ju, Yeon Ha, Park, Mingu Gordon, Lee, C Justin

“…Monoamine oxidase-B (MAOB) has been believed to mediate the degradation of monoamine neurotransmitters such as dopamine. However, this traditional belief has…”
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