Search Results - "Justement, J Shawn"

A Longitudinal Study of COVID-19 Sequelae and Immunity: Baseline Findings by Sneller, Michael C, Liang, C Jason, Marques, Adriana R, Chung, Joyce Y, Shanbhag, Sujata M, Fontana, Joseph R, Raza, Haniya, Okeke, Onyi, Dewar, Robin L, Higgins, Bryan P, Tolstenko, Katie, Kwan, Richard W, Gittens, Kathleen R, Seamon, Catherine A, McCormack, Genevieve, Shaw, Jacob S, Okpali, Grace M, Law, Melissa, Trihemasava, Krittin, Kennedy, Brooke D, Shi, Victoria, Justement, J Shawn, Buckner, Clarisa M, Blazkova, Jana, Moir, Susan, Chun, Tae-Wook, Lane, H Clifford

“…A substantial proportion of persons who develop COVID-19 report persistent symptoms after acute illness. Various pathophysiologic mechanisms have been…”
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Relationship Between Residual Plasma Viremia and the Size of HIV Proviral DNA Reservoirs in Infected Individuals Receiving Effective Antiretroviral Therapy by Chun, Tae-Wook, Murray, Danielle, Justement, J. Shawn, Hallahan, Claire W., Moir, Susan, Kovacs, Colin, Fauci, Anthony S.

“…Residual plasma viremia (<50 copies/mL) persists in certain human immunodeficiency virus (HIV)–infected individuals receiving antiretroviral therapy (ART);…”
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Distinct mechanisms of long-term virologic control in two HIV-infected individuals after treatment interruption of anti-retroviral therapy by Blazkova, Jana, Gao, Feng, Marichannegowda, Manukumar Honnayakanahalli, Justement, J. Shawn, Shi, Victoria, Whitehead, Emily J., Schneck, Rachel F., Huiting, Erin D., Gittens, Kathleen, Cottrell, Mackenzie, Benko, Erika, Kovacs, Colin, Lack, Justin, Sneller, Michael C., Moir, Susan, Fauci, Anthony S., Chun, Tae-Wook

“…Certain infected individuals suppress human immunodeficiency virus (HIV) in the absence of anti-retroviral therapy (ART). Elucidating the underlying…”
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Effect of analytical treatment interruption and reinitiation of antiretroviral therapy on HIV reservoirs and immunologic parameters in infected individuals by Clarridge, Katherine E, Blazkova, Jana, Einkauf, Kevin, Petrone, Mary, Refsland, Eric W, Justement, J Shawn, Shi, Victoria, Huiting, Erin D, Seamon, Catherine A, Lee, Guinevere Q, Yu, Xu G, Moir, Susan, Sneller, Michael C, Lichterfeld, Mathias, Chun, Tae-Wook

“…Therapeutic strategies aimed at achieving antiretroviral therapy (ART)-free HIV remission in infected individuals are under active investigation. Considering…”
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Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient by Yukl, Steven A, Boritz, Eli, Busch, Michael, Bentsen, Christopher, Chun, Tae-Wook, Douek, Daniel, Eisele, Evelyn, Haase, Ashley, Ho, Ya-Chi, Hütter, Gero, Justement, J Shawn, Keating, Sheila, Lee, Tzong-Hae, Li, Peilin, Murray, Danielle, Palmer, Sarah, Pilcher, Christopher, Pillai, Satish, Price, Richard W, Rothenberger, Meghan, Schacker, Timothy, Siliciano, Janet, Siliciano, Robert, Sinclair, Elizabeth, Strain, Matt, Wong, Joseph, Richman, Douglas, Deeks, Steven G

“…There is intense interest in developing curative interventions for HIV. How such a cure will be quantified and defined is not known. We applied a series of…”
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Glycosylation, Hypogammaglobulinemia, and Resistance to Viral Infections by Sadat, Mohammed A, Moir, Susan, Chun, Tae-Wook, Lusso, Paolo, Kaplan, Gerardo, Wolfe, Lynne, Memoli, Matthew J, He, Miao, Vega, Hugo, Kim, Leo J.Y, Huang, Yan, Hussein, Nadia, Nievas, Elma, Mitchell, Raquel, Garofalo, Mary, Louie, Aaron, Ireland, Derek C, Grunes, Claire, Cimbro, Raffaello, Patel, Vyomesh, Holzapfel, Genevieve, Salahuddin, Daniel, Bristol, Tyler, Adams, David, Marciano, Beatriz E, Hegde, Madhuri, Li, Yuxing, Calvo, Katherine R, Stoddard, Jennifer, Justement, J. Shawn, Jacques, Jerome, Long Priel, Debra A, Murray, Danielle, Sun, Peter, Kuhns, Douglas B, Boerkoel, Cornelius F, Chiorini, John A, Di Pasquale, Giovanni, Verthelyi, Daniela, Rosenzweig, Sergio D

“…In two siblings, a congenital disorder of glycosylation (CDG-IIb) was shown to lead to severe hypogammaglobulinemia but paradoxically impaired viral…”
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Effect of Antiretroviral Therapy on HIV Reservoirs in Elite Controllers by Chun, Tae-Wook, Justement, J. Shawn, Murray, Danielle, Kim, Connie J., Blazkova, Jana, Hallahan, Claire W., Benko, Erika, Costiniuk, Cecilia T., Kandel, Gabor, Ostrowski, Mario, Kaul, Rupert, Moir, Susan, Casazza, Joseph P., Koup, Richard A., Kovacs, Colin, Fauci, Anthony S.

“…Elite controllers suppress human immunodeficiency virus (HIV) viremia to below the limit of detection in the absence of antiretroviral therapy (ART). However,…”
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Glycan-dependent HIV-specific neutralizing antibodies bind to cells of uninfected individuals by Blazkova, Jana, Refsland, Eric W, Clarridge, Katherine E, Shi, Victoria, Justement, J Shawn, Huiting, Erin D, Gittens, Kathleen R, Chen, Xuejun, Schmidt, Stephen D, Liu, Cuiping, Doria-Rose, Nicole, Mascola, John R, Heredia, Alonso, Moir, Susan, Chun, Tae-Wook

“…A number of highly potent and broadly neutralizing antibodies (bNAbs) against the human immunodeficiency virus (HIV) have recently been shown to prevent…”
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Maintenance of HIV-Specific Memory B-Cell Responses in Elite Controllers Despite Low Viral Burdens by Buckner, Clarisa M., Kardava, Lela, Zhang, Xiaozhen, Gittens, Kathleen, Justement, J. Shawn, Kovacs, Colin, McDermott, Adrian B., Li, Yuxing, Sajadi, Mohammad M., Chun, Tae-Wook, Fauci, Anthony S., Moir, Susan

“…Human immunodeficiency virus (HIV)-specific B-cell responses in infected individuals are maintained by active HIV replication.Suppression of viremia by…”
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Paucity of HIV DNA Methylation in Latently Infected, Resting CD4+ T Cells from Infected Individuals Receiving Antiretroviral Therapy by BLAZKOVA, Jana, MURRAY, Danielle, JUSTEMENT, J. Shawn, FUNK, Emily K, NELSON, Amy K, MOIR, Susan, CHUN, Tae-Wook, FAUCI, Anthony S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Decay of the HIV Reservoir in Patients Receiving Antiretroviral Therapy for Extended Periods: Implications for Eradication of Virus by Chun, Tae-Wook, Justement, J. Shawn, Moir, Susan, Hallahan, Claire W., Maenza, Janine, Mullins, James I., Collier, Ann C., Corey, Lawrence, Fauci, Anthony S.

“…The persistence of latently infected resting CD4+ T cells has been clearly demonstrated in human immunodeficiency virus (HIV)—infected individuals receiving…”
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Impact of Treatment Interruption on HIV Reservoirs and Lymphocyte Subsets in Individuals Who Initiated Antiretroviral Therapy During the Early Phase of Infection by Huiting, Erin D, Gittens, Kathleen, Justement, J Shawn, Shi, Victoria, Blazkova, Jana, Benko, Erika, Kovacs, Colin, Wender, Paul A, Moir, Susan, Sneller, Michael C, Fauci, Anthony S, Chun, Tae-Wook

“…Therapeutic strategies for achieving sustained virologic remission are being explored in human immunodeficiency virus (HIV)-infected individuals who began…”
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Effect of Histone Deacetylase Inhibitors on HIV Production in Latently Infected, Resting CD4⁺ T Cells From Infected Individuals Receiving Effective Antiretroviral Therapy by Blazkova, Jana, Chun, Tae-Wook, Belay, Bietel W., Murray, Danielle, Justement, J. Shawn, Funk, Emily K., Nelson, Amy, Hallahan, Claire W., Moir, Susan, Wender, Paul A., Fauci, Anthony S.

“…Persistence of the latent viral reservoir has been recognized as a major obstacle to eradicating human immunodeficiency virus (HIV) in infected individuals…”
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Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy by Chun, Tae-Wook, Davey, Richard T, Ostrowski, Mario, Shawn Justement, J, Engel, Delphine, Mullins, James I, Fauci, Anthony S

“…We examined the pathogenic significance of the latent viral reservoir in the resting CD4+ T cell compartment of HIV-1-infected individuals as well as its…”
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Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily by Moir, Susan, Malaspina, Angela, Pickeral, Oxana K, Donoghue, Eileen T, Vasquez, Joshua, Miller, Natalie J, Krishnan, Surekha R, Planta, Marie A, Turney, John F, Justement, J Shawn, Kottilil, Shyamasundaran, Dybul, Mark, Mican, JoAnn M, Kovacs, Colin, Chun, Tae-Wook, Birse, Charles E, Fauci, Anthony S

“…Human immunodeficiency virus (HIV) infection leads to numerous perturbations of B cells through mechanisms that remain elusive. We performed DNA microarray,…”
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Impact of HIV on cell survival and antiviral activity of plasmacytoid dendritic cells by Meyers, Jennifer Hartt, Justement, J Shawn, Hallahan, Claire W, Blair, Eric T, Sun, Yongming A, O'Shea, M Angeline, Roby, Gregg, Kottilil, Shyam, Moir, Susan, Kovacs, Colin M, Chun, Tae-Wook, Fauci, Anthony S

“…Plasmacytoid dendritic cells (pDCs) are important mediators of innate immunity that act mainly through secretion of interferon (IFN)-alpha. Previous studies…”
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Gene Expression and Viral Prodution in Latently Infected, Resting CD4+T Cells in Viremic versus Aviremic HIV-Infected Individuals by Chun, Tae-Wook, Justement, J. Shawn, Lempicki, Richard A., Yang, Jun, Dennis, Glynn, Hallahan, Claire W., Sanford, Christina, Pandya, Punita, Liu, Shuying, McLaughlin, Mary, Ehler, Linda A., Moir, Susan, Fauci, Anthony S.

“…The presence of HIV-1 in latently infected, resting CD4+T cells has been clearly demonstrated in infected individuals; however, the extent of viral expression…”
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Combination anti-HIV antibodies provide sustained virological suppression by Sneller, Michael C., Blazkova, Jana, Justement, J. Shawn, Shi, Victoria, Kennedy, Brooke D., Gittens, Kathleen, Tolstenko, Jekaterina, McCormack, Genevieve, Whitehead, Emily J., Schneck, Rachel F., Proschan, Michael A., Benko, Erika, Kovacs, Colin, Oguz, Cihan, Seaman, Michael S., Caskey, Marina, Nussenzweig, Michel C., Fauci, Anthony S., Moir, Susan, Chun, Tae-Wook

“…Antiretroviral therapy is highly effective in suppressing human immunodeficiency virus (HIV) 1 . However, eradication of the virus in individuals with HIV has…”
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Relationship between the Size of the Human Immunodeficiency Virus Type 1 (HIV-1) Reservoir in Peripheral Blood CD4+ T Cells and CD4+:CD8+ T Cell Ratios in Aviremic HIV-1-Infected Individuals Receiving Long-Term Highly Active Antiretroviral Therapy by Chun, Tae-Wook, Justement, J. Shawn, Pandya, Punita, Hallahan, Claire W., McLaughlin, Mary, Liu, Shuying, Ehler, Linda A., Kovacs, Colin, Fauci, Anthony S.

“…It has been demonstrated that human immunodeficiency virus type 1 (HIV-1) replication persists in most infected individuals receiving highly active…”
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Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption by Bar, Katharine J, Sneller, Michael C, Harrison, Linda J, Justement, J. Shawn, Overton, Edgar T, Petrone, Mary E, Salantes, D. Brenda, Seamon, Catherine A, Scheinfeld, Benjamin, Kwan, Richard W, Learn, Gerald H, Proschan, Michael A, Kreider, Edward F, Blazkova, Jana, Bardsley, Mark, Refsland, Eric W, Messer, Michael, Clarridge, Katherine E, Tustin, Nancy B, Madden, Patrick J, Oden, KaSaundra, O’Dell, Sijy J, Jarocki, Bernadette, Shiakolas, Andrea R, Tressler, Randall L, Doria-Rose, Nicole A, Bailer, Robert T, Ledgerwood, Julie E, Capparelli, Edmund V, Lynch, Rebecca M, Graham, Barney S, Moir, Susan, Koup, Richard A, Mascola, John R, Hoxie, James A, Fauci, Anthony S, Tebas, Pablo, Chun, Tae-Wook

“…In these trials, passive administration of VRC01, a broadly neutralizing antibody against human immunodeficiency virus that targets the HIV CD4-binding site,…”
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