Search Results - "Just, Lothar"

Large-scale tissue clearing (PACT): Technical evaluation and new perspectives in immunofluorescence, histology and ultrastructure by Neckel, Peter H., Mattheus, Ulrich, Hirt, Bernhard, Just, Lothar, Mack, Andreas F.

“…Novel techniques, like CLARITY and PACT, render large tissue specimens transparent and thereby suitable for microscopic analysis. We used these techniques to…”
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Generation of pluripotent stem cells from adult human testis by Skutella, Thomas, Conrad, Sabine, Renninger, Markus, Hennenlotter, Jörg, Wiesner, Tina, Just, Lothar, Bonin, Michael, Aicher, Wilhelm, Bühring, Hans-Jörg, Mattheus, Ulrich, Mack, Andreas, Wagner, Hans-Joachim, Minger, Stephen, Matzkies, Matthias, Reppel, Michael, Hescheler, Jürgen, Sievert, Karl-Dietrich, Stenzl, Arnulf

“…Human primordial germ cells and mouse neonatal and adult germline stem cells are pluripotent and show similar properties to embryonic stem cells. Here we…”
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Human placenta and bone marrow derived MSC cultured in serum-free, b-FGF-containing medium express cell surface frizzled-9 and SSEA-4 and give rise to multilineage differentiation by Battula, Venkata Lokesh, Bareiss, Petra M., Treml, Sabrina, Conrad, Sabine, Albert, Ingrid, Hojak, Sigrid, Abele, Harald, Schewe, Bernhard, Just, Lothar, Skutella, Thomas, Bühring, Hans-Jörg

“…Conventionally, mesenchymal stem cells (MSC) are generated by plating cells from bone marrow (BM) or other sources into culture flasks and selecting…”
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Isolation, expansion and transplantation of postnatal murine progenitor cells of the enteric nervous system by Dettmann, Heike Monika, Zhang, Ying, Wronna, Nadine, Kraushaar, Udo, Guenther, Elke, Mohr, Roland, Neckel, Peter Helmut, Mack, Andreas, Fuchs, Joerg, Just, Lothar, Obermayr, Florian

“…Neural stem or progenitor cells have been proposed to restore gastrointestinal function in patients suffering from congenital or acquired defects of the…”
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Comparative Microarray Analysis of Proliferating and Differentiating Murine ENS Progenitor Cells by Hirt, Bernhard, Zhang, Ying, Mohr, Roland, Neckel, Peter Helmut, Just, Lothar

“…Postnatal neural progenitor cells of the enteric nervous system are a potential source for future cell replacement therapies of developmental dysplasia like…”
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RGMa inhibits neurite outgrowth of neuronal progenitors from murine enteric nervous system via the neogenin receptor in vitro by Metzger, Marco, Conrad, Sabine, Skutella, Thomas, Just, Lothar

“…The enteric nervous system (ENS) in vertebrate embryos is formed by neural crest‐derived cells. During development, these cells undergo extensive migration…”
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Wnt Receptor Frizzled-4 as a Marker for Isolation of Enteric Neural Progenitors in Human Children by Neckel, Peter H, Scharr, Melanie, Seid, Karin, Nothelfer, Katharina, Fuchs, Jörg, Obermayr, Florian, Hirt, Bernhard, Huber, Stephan M, Just, Lothar

“…Identification and isolation of neural progenitor cells from the human enteric nervous system (ENS) is currently hampered by the lack of reliable, specific…”
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Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1 by Huang, Dan Yang, Boini, Krishna M, Friedrich, Björn, Metzger, Marco, Just, Lothar, Osswald, Hartmut, Wulff, Peer, Kuhl, Dietmar, Vallon, Volker, Lang, Florian

“…Serum- and glucocorticoid-inducible kinase (SGK1) is transcriptionally upregulated by mineralocorticoids and activated by insulin. The kinase stimulates the…”
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Expression of the Wnt Receptor Frizzled-4 in the Human Enteric Nervous System of Infants by Just, Lothar, Bühring, Hans-Jörg, Bareiss, Petra M., Reinartz, Ellen, Belz, Nadine, Obermayr, Florian, Nothelfer, Katharina, Beschorner, Rudi

“…The Wnt signalling pathway plays a crucial role in the development of the nervous system. This signalling cascade is initiated upon binding of the secreted Wnt…”
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SGK1-sensitive renal tubular glucose reabsorption in diabetes by Ackermann, Teresa F, Boini, Krishna M, Völkl, Harald, Bhandaru, Madhuri, Bareiss, Petra M, Just, Lothar, Vallon, Volker, Amann, Kerstin, Kuhl, Dietmar, Feng, Yuxi, Hammes, Hans-Peter, Lang, Florian

“…The hyperglycemia of diabetes mellitus increases the filtered glucose load beyond the maximal tubular transport rate and thus leads to glucosuria. Sustained…”
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Dopaminergic properties and function after grafting of attached neural precursor cultures by Timmer, Marco, Grosskreutz, Julian, Schlesinger, Friedrich, Krampfl, Klaus, Wesemann, Maike, Just, Lothar, Bufler, Johannes, Grothe, Claudia

“…Generation of dopaminergic (DA) neurons from multipotent embryonic progenitors represents a promising therapeutical strategy for Parkinson's disease (PD). Aim…”
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Glucocorticoid adrenal steroids and glucocorticoid-inducible kinase isoforms in the regulation of GluR6 expression by Strutz‐Seebohm, Nathalie, Seebohm, Guiscard, Shumilina, Ekaterina, Mack, Andreas F., Wagner, Hans‐Joachim, Lampert, Angelika, Grahammer, Florian, Henke, Guido, Just, Lothar, Skutella, Thomas, Hollmann, Michael, Lang, Florian

“…Generation of memory is enhanced during stress, an effect attributed to stimulation of neuronal learning by adrenal glucocorticoids. The…”
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Regulation of GluR1 abundance in murine hippocampal neurones by serum- and glucocorticoid-inducible kinase 3 by Strutz‐Seebohm, Nathalie, Seebohm, Guiscard, Mack, Andreas F., Wagner, Hans‐Joachim, Just, Lothar, Skutella, Thomas, Lang, Undine E., Henke, Guido, Striegel, Marion, Hollmann, Michael, Rouach, Nathalie, Nicoll, Roger A., McCormick, James A., Wang, Jian, Pearce, David, Lang, Florian

“…Phosphatidylinositol 3 kinase (PI3-kinase) is activated during and is required for hippocampal glutamate receptor-dependent long-term potentiation. It mediates…”
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Activation of Wnt Signaling Increases Numbers of Enteric Neurons Derived From Neonatal Mouse and Human Progenitor Cells by Zhang, Ying, Seid, Karin, Obermayr, Florian, Just, Lothar, Neckel, Peter H

“…Background & Aims Neural stem and progenitor cells from the enteric nervous system (ENS) might serve as a source of cells for treatment of…”
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White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies by Burns, Alan J., Goldstein, Allan M., Newgreen, Donald F., Stamp, Lincon, Schäfer, Karl-Herbert, Metzger, Marco, Hotta, Ryo, Young, Heather M., Andrews, Peter W., Thapar, Nikhil, Belkind-Gerson, Jaime, Bondurand, Nadege, Bornstein, Joel C., Chan, Wood Yee, Cheah, Kathryn, Gershon, Michael D., Heuckeroth, Robert O., Hofstra, Robert M.W., Just, Lothar, Kapur, Raj P., King, Sebastian K., McCann, Conor J., Nagy, Nandor, Ngan, Elly, Obermayr, Florian, Pachnis, Vassilis, Pasricha, Pankaj J., Sham, Mai Har, Tam, Paul, Vanden Berghe, Pieter

“…Over the last 20 years, there has been increasing focus on the development of novel stem cell based therapies for the treatment of disorders and diseases…”
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Expansion and Differentiation of Neural Progenitors Derived From the Human Adult Enteric Nervous System by Metzger, Marco, Bareiss, Petra M, Danker, Timm, Wagner, Silvia, Hennenlotter, Joerg, Guenther, Elke, Obermayr, Florian, Stenzl, Arnulf, Koenigsrainer, Alfred, Skutella, Thomas, Just, Lothar

“…Background & Aims Neural stem and progenitor cells from the enteric nervous system have been proposed for use in cell-based therapies against specific…”
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Organotypical Tissue Cultures from Fetal and Neonatal Murine Colon by Neckel, Peter H, Just, Lothar

“…The complex functions of the gastrointestinal tract rely on the coordinated interplay of several cell and tissue types involving epithelium, connective tissue,…”
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In vivo biocompatibility and biodegradation of a novel thin and mechanically stable collagen scaffold by Rahmanian-Schwarz, Afshin, Held, Manuel, Knoeller, Tabea, Stachon, Susanne, Schmidt, Timo, Schaller, Hans-Eberhard, Just, Lothar

“…The demand for scaffolds comprised of natural materials such as collagen has increased in recent years. However, many scaffolds rely on chemical or physical…”
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Bone marrow-derived human mesenchymal stem cells express cardiomyogenic proteins but do not exhibit functional cardiomyogenic differentiation potential by Siegel, Georg, Krause, Petra, Wöhrle, Stefanie, Nowak, Patrick, Ayturan, Miriam, Kluba, Torsten, Brehm, Bernhard R, Neumeister, Birgid, Köhler, David, Rosenberger, Peter, Just, Lothar, Northoff, Hinnak, Schäfer, Richard

“…Despite their paracrine activites, cardiomyogenic differentiation of bone marrow (BM)-derived mesenchymal stem cells (MSCs) is thought to contribute to cardiac…”
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Neuroprotective effects of erythropoietin on 6-hydroxydopamine-treated ventral mesencephalic dopamine-rich cultures by Ganser, Claudia, Papazoglou, Anna, Just, Lothar, Nikkhah, Guido

“…Parkinson's disease (PD) is a neurodegenerative disorder with motor symptoms caused by the loss of dopaminergic (DA) cells and consequently dopamine release in…”
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