Search Results - "Jusakul, Apinya"

Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma by Jusakul, Apinya, Cutcutache, Ioana, Yong, Chern Han, Lim, Jing Quan, Huang, Mi Ni, Padmanabhan, Nisha, Nellore, Vishwa, Kongpetch, Sarinya, Ng, Alvin Wei Tian, Ng, Ley Moy, Choo, Su Pin, Myint, Swe Swe, Thanan, Raynoo, Nagarajan, Sanjanaa, Lim, Weng Khong, Ng, Cedric Chuan Young, Boot, Arnoud, Liu, Mo, Ong, Choon Kiat, Rajasegaran, Vikneswari, Lie, Stefanus, Lim, Alvin Soon Tiong, Lim, Tse Hui, Tan, Jing, Loh, Jia Liang, McPherson, John R, Khuntikeo, Narong, Bhudhisawasdi, Vajaraphongsa, Yongvanit, Puangrat, Wongkham, Sopit, Totoki, Yasushi, Nakamura, Hiromi, Arai, Yasuhito, Yamasaki, Satoshi, Chow, Pierce Kah-Hoe, Chung, Alexander Yaw Fui, Ooi, London Lucien Peng Jin, Lim, Kiat Hon, Dima, Simona, Duda, Dan G, Popescu, Irinel, Broet, Philippe, Hsieh, Sen-Yung, Yu, Ming-Chin, Scarpa, Aldo, Lai, Jiaming, Luo, Di-Xian, Carvalho, André Lopes, Vettore, André Luiz, Rhee, Hyungjin, Park, Young Nyun, Alexandrov, Ludmil B, Gordân, Raluca, Rozen, Steven G, Shibata, Tatsuhiro, Pairojkul, Chawalit, Teh, Bin Tean, Tan, Patrick

“…Cholangiocarcinoma (CCA) is a hepatobiliary malignancy exhibiting high incidence in countries with endemic liver-fluke infection. We analyzed 489 CCAs from 10…”
Get more information

Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors by Huang, Mi Ni, Yu, Willie, Teoh, Wei Wei, Ardin, Maude, Jusakul, Apinya, Ng, Alvin Wei Tian, Boot, Arnoud, Abedi-Ardekani, Behnoush, Villar, Stephanie, Myint, Swe Swe, Othman, Rashidah, Poon, Song Ling, Heguy, Adriana, Olivier, Magali, Hollstein, Monica, Tan, Patrick, Teh, Bin Tean, Sabapathy, Kanaga, Zavadil, Jiri, Rozen, Steven G

“…Aflatoxin B1 (AFB1) is a mutagen and IARC (International Agency for Research on Cancer) Group 1 carcinogen that causes hepatocellular carcinoma (HCC). Here, we…”
Get full text

Overexpression of microRNA-205-5p promotes cholangiocarcinoma growth by reducing expression of homeodomain-interacting protein kinase 3 by Mon, Aye Myat, Intuyod, Kitti, Klungsaeng, Sirinapha, Jusakul, Apinya, Pongking, Thatsanapong, Lert-itthiporn, Worachart, Luvira, Vor, Pairojkul, Chawalit, Plengsuriyakarn, Tullayakorn, Na-Bangchang, Kesara, Pinlaor, Somchai, Pinlaor, Porntip

“…The microRNA miR-205-5p has diverse effects in different malignancies, including cholangiocarcinoma (CCA), but its effects on CCA progression is unclear. Here…”
Get full text

Buparlisib and ponatinib inhibit aggressiveness of cholangiocarcinoma cells via suppression of IRS1-related pathway by targeting oxidative stress resistance by Kaewlert, Waleeporn, Sakonsinsiri, Chadamas, Lert-itthiporn, Worachart, Mahalapbutr, Panupong, Ali, Saba, Rungrotmongkol, Thanyada, Jusakul, Apinya, Armartmuntree, Napat, Pairojkul, Chawalit, Feng, Guofei, Ma, Ning, Pinlaor, Somchai, Murata, Mariko, Thanan, Raynoo

“…Cholangiocarcinoma (CCA) is an oxidative stress-driven liver cancer with bile duct epithelial cell phenotypes and currently lacks effective treatments, making…”
Get full text

Arctigenin inhibits cholangiocarcinoma progression by regulating cell migration and cell viability via the N-cadherin and apoptosis pathway by Janthamala, Sutthiwan, Jusakul, Apinya, Kongpetch, Sarinya, Kimawaha, Phongsaran, Klanrit, Poramate, Loilome, Watcharin, Namwat, Nisana, Techasen, Anchalee

“…Northeast Thailand has the highest incidence of cholangiocarcinoma (CCA) in the world. The lack of promising diagnostic markers and appropriate therapeutic…”
Get full text

A combination of monosodium glutamate and high-fat and high-fructose diets increases the risk of kidney injury, gut dysbiosis and host-microbial co-metabolism by Pongking, Thatsanapong, Haonon, Ornuma, Dangtakot, Rungtiwa, Onsurathum, Sudarat, Jusakul, Apinya, Intuyod, Kitti, Sangka, Arunnee, Anutrakulchai, Sirirat, Cha'on, Ubon, Pinlaor, Somchai, Pinlaor, Porntip

“…Consumption of either monosodium glutamate (MSG) or high-fat and high-fructose (HFF) diets changes the gut microbiome and hence contributes to development of…”
Get full text

Mechanisms of oxysterol-induced carcinogenesis by Jusakul, Apinya, Yongvanit, Puangrat, Loilome, Watcharin, Namwat, Nisana, Kuver, Rahul

“…Oxysterols are oxidation products of cholesterol that are generated by enzymatic reactions mediated by cytochrome P450 family enzymes or by non-enzymatic…”
Get full text

Therapeutic targeting of ARID1A and PI3K/AKT pathway alterations in cholangiocarcinoma by Tessiri, Supharada, Techasen, Anchalee, Kongpetch, Sarinya, Namjan, Achira, Loilome, Watcharin, Chan-On, Waraporn, Thanan, Raynoo, Jusakul, Apinya

“…Genetic alterations in were detected at a high frequency in cholangiocarcinoma (CCA). Growing evidence indicates that the loss of ARID1A expression leads to…”
Get full text

Prognostic Values of Ferroptosis-Related Proteins ACSL4, SLC7A11, and CHAC1 in Cholangiocarcinoma by Amontailak, Supakan, Titapun, Attapol, Jusakul, Apinya, Thanan, Raynoo, Kimawaha, Phongsaran, Jamnongkan, Wassana, Thanee, Malinee, Sirithawat, Papitchaya, Techasen, Anchalee

“…The epithelial malignant tumor known as cholangiocarcinoma (CCA) is most commonly found in Southeast Asia, particularly in northeastern Thailand. Previous…”
Get full text

Vitamin C supplementation reduces expression of circulating miR-451a in subjects with poorly controlled type 2 diabetes mellitus and high oxidative stress by Ruknarong, Laongthip, Boonthongkaew, Chongchira, Chuangchot, Nisa, Jumnainsong, Amonrat, Leelayuwat, Naruemon, Jusakul, Apinya, Gaudieri, Silvana, Leelayuwat, Chanvit

“…Vitamin C is an essential element required for normal metabolic function. We investigated the effect of vitamin C supplementation on circulating miRNA (miR)…”
Get full text

Establishment of a Potential Serum Biomarker Panel for the Diagnosis and Prognosis of Cholangiocarcinoma Using Decision Tree Algorithms by Kimawaha, Phongsaran, Jusakul, Apinya, Junsawang, Prem, Thanan, Raynoo, Titapun, Attapol, Khuntikeo, Narong, Techasen, Anchalee

“…Potential biomarkers which include S100 calcium binding protein A9 (S100A9), mucin 5AC (MUC5AC), transforming growth factor β1 (TGF-β1), and angiopoietin-2…”
Get full text

Iron-induced kidney cell damage: insights into molecular mechanisms and potential diagnostic significance of urinary FTL by Punchai, Soraya, Chaiyagot, Nachayada, Artkaew, Nadthanicha, Jusakul, Apinya, Cha'on, Ubon, Thanan, Raynoo, Vaeteewoottacharn, Kulthida, Lert-Itthiporn, Worachart

“…Iron overload can lead to organ and cell injuries. Although the mechanisms of iron-induced cell damage have been extensively studied using various cells,…”
Get full text

Establishment of cholangiocarcinoma cell lines from patients in the endemic area of liver fluke infection in Thailand by Saensa-ard, Sunitta, Leuangwattanawanit, Saman, Senggunprai, Laddawan, Namwat, Nisana, Kongpetch, Sarinya, Chamgramol, Yaovalux, Loilome, Watcharin, Khansaard, Walaiporn, Jusakul, Apinya, Prawan, Auemduan, Pairojkul, Chawalit, Khantikeo, Narong, Yongvanit, Puangrat, Kukongviriyapan, Veerapol

“…Cholangiocarcinoma is a rare type of cancer which is an increasingly discernible health threat. The disease is usually very difficult in diagnosis and various…”
Get full text

Circulating TGF-β1 as the potential epithelial mesenchymal transition-biomarker for diagnosis of cholangiocarcinoma by Kimawaha, Phongsaran, Jusakul, Apinya, Junsawang, Prem, Loilome, Watcharin, Khuntikeo, Narong, Techasen, Anchalee

“…Cholangiocarcinoma (CCA) is a malignant tumor arising from bile duct epithelium. The oncogenic risk factor is infection by the liver fluke, (Ov). One of key…”
Get full text

Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma by Qamra, Aditi, Xing, Manjie, Padmanabhan, Nisha, Kwok, Jeffrey Jun Ting, Zhang, Shenli, Xu, Chang, Leong, Yan Shan, Lee Lim, Ai Ping, Tang, Qianqao, Ooi, Wen Fong, Suling Lin, Joyce, Nandi, Tannistha, Yao, Xiaosai, Ong, Xuewen, Lee, Minghui, Tay, Su Ting, Keng, Angie Tan Lay, Gondo Santoso, Erna, Ng, Cedric Chuan Young, Ng, Alvin, Jusakul, Apinya, Smoot, Duane, Ashktorab, Hassan, Rha, Sun Young, Yeoh, Khay Guan, Peng Yong, Wei, Chow, Pierce K H, Chan, Weng Hoong, Ong, Hock Soo, Soo, Khee Chee, Kim, Kyoung-Mee, Wong, Wai Keong, Rozen, Steven G, Teh, Bin Tean, Kappei, Dennis, Lee, Jeeyun, Connolly, John, Tan, Patrick

“…Promoter elements play important roles in isoform and cell type-specific expression. We surveyed the epigenomic promoter landscape of gastric adenocarcinoma,…”
Get more information

Pathogenesis of cholangiocarcinoma: From genetics to signalling pathways by Kongpetch, Sarinya, PhD, Jusakul, Apinya, PhD, Ong, Choon Kiat, PhD, Lim, Weng Khong, PhD, Rozen, Steven G., PhD, Tan, Patrick, MD, PhD, Teh, Bin Tean, MD, PhD

“…Abstract Cholangiocarcinoma (CCA) is a malignant tumour of bile duct epithelial cells with dismal prognosis and rising incidence. Chronic inflammation…”
Get full text

Tissue Microbiome Profiling Identifies an Enrichment of Specific Enteric Bacteria in Opisthorchis viverrini Associated Cholangiocarcinoma by Chng, Kern Rei, Chan, Sock Hoai, Ng, Amanda Hui Qi, Li, Chenhao, Jusakul, Apinya, Bertrand, Denis, Wilm, Andreas, Choo, Su Pin, Tan, Damien Meng Yew, Lim, Kiat Hon, Soetinko, Roy, Ong, Choon Kiat, Duda, Dan G., Dima, Simona, Popescu, Irinel, Wongkham, Chaisiri, Feng, Zhu, Yeoh, Khay Guan, Teh, Bin Tean, Yongvanit, Puangrat, Wongkham, Sopit, Bhudhisawasdi, Vajaraphongsa, Khuntikeo, Narong, Tan, Patrick, Pairojkul, Chawalit, Ngeow, Joanne, Nagarajan, Niranjan

“…Cholangiocarcinoma (CCA) is the primary cancer of the bile duct system. The role of bile duct tissue microbiomes in CCA tumorigenesis is unestablished. To…”
Get full text

Lack of Targetable FGFR2 Fusions in Endemic Fluke-Associated Cholangiocarcinoma by Kongpetch, Sarinya, Jusakul, Apinya, Lim, Jing Quan, Ng, Cedric Chuan Young, Chan, Jason Yongsheng, Rajasegaran, Vikneswari, Lim, Tse Hui, Lim, Kiat Hon, Choo, Su Pin, Dima, Simona, Popescu, Irinel, Duda, Dan G, Kukongviriyapan, Veerapol, Khuntikeo, Narong, Pairojkul, Chawalit, Rozen, Steven G, Tan, Patrick, Teh, Bin Tean

“…Cholangiocarcinoma (CCA) remains a disease with poor prognosis and limited therapeutic options. Identification of driver genetic alterations may lead to the…”
Get full text

Anticancer properties and metabolomic profiling of Shorea roxburghii extracts toward gastrointestinal cancer cell lines by Janthamala, Sutthiwan, Promraksa, Bundit, Thanee, Malinee, Duenngai, Kunyarat, Jusakul, Apinya, Kongpetch, Sarinya, Kraiklang, Ratthaphol, Thanee, Kidsada, Pinlaor, Porntip, Namwat, Nisana, Saya, Hideyuki, Techasen, Anchalee

“…Gastrointestinal cancer (GIC) ranks as the highest cause of cancer-related deaths globally. GIC patients are often diagnosed at advanced stages, limiting…”
Get full text

Serum Angiopoietin-Like Protein 4: A Potential Prognostic Biomarker for Prediction of Vascular Invasion and Lymph Node Metastasis in Cholangiocarcinoma Patients by Aung, Tin May, Ciin, Mang Ngaih, Silsirivanit, Atit, Jusakul, Apinya, Lert-Itthiporn, Worachart, Proungvitaya, Tanakorn, Roytrakul, Sittiruk, Proungvitaya, Siriporn

“…Cholangiocarcinoma (CCA) is a tumor arising from cholangiocytes lining the bile ducts. Vascular invasion and lymph node metastasis are important prognostic…”
Get full text