Search Results - "Jurutka, P.W."

Association between polymorphic variation in VDR and RXRA and circulating levels of vitamin D metabolites by Hibler, E.A., Jurutka, P.W., Egan, J.B., Hu, C., LeRoy, E.C., Martinez, M.E., Thompson, P.A., Jacobs, E.T.

“…The vitamin D metabolite 1,25(OH) 2D is the bioactive ligand of the vitamin D receptor (VDR). VDR forms a heterodimer with the retinoid X receptors (RXRs) that…”
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Phosphorylation of the human vitamin D receptor by protein kinase C. Biochemical and functional evaluation of the serine 51 recognition site by JUI-CHENG HSIEH, JURUTKA, P. W, NAKAJIMA, S, GALLIGAN, M. A, HAUSSLER, C. A, SHIMIZU, Y, SHIMIZU, N, WHITFIELD, G. K, HAUSSLER, M. R

“…We have reported previously that the human vitamin D receptor (hVDR) is selectively phosphorylated by protein kinase C-beta (PKC-beta), in vitro, on a serine…”
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Human vitamin D receptor phosphorylation by casein kinase II at Ser-208 potentiates transcriptional activation by Jurutka, P.W. (University of Arizona, Tucson, AZ.), Hsieh, J.C, Nakajima, S, Haussler, C.A, Whitfield, G.K, Haussler, M.R

“…The potential functional significance of human 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] receptor (hVDR) phosphorylation at Ser-208 was evaluated by…”
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New understanding of the molecular mechanism of receptor-mediated genomic actions of the vitamin D hormone by Haussler, M R, Jurutka, P W, Hsieh, J C, Thompson, P D, Selznick, S H, Haussler, C A, Whitfield, G K

“…The nuclear vitamin D receptor (VDR) binds the 1,25-dihydroxyvitamin D3 [1,25(OH)2D3]hormone with high affinity and elicits its actions to regulate gene…”
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Phosphorylation of serine 208 in the human vitamin D receptor. The predominant amino acid phosphorylated by casein kinase II, in vitro, and identification as a significant phosphorylation site in intact cells by JURUTKA, P. W, JUI-CHENG HSIEH, MACDONALD, P. N, TERPENING, C. M, HAUSSLER, C. A, HAUSSLER, M. R, WHITFIELD, G. K

“…The human 1,25-dihydroxyvitamin D3 receptor (hVDR), like other members of the steroid/thyroid receptor superfamily, has been observed to undergo rapid…”
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The T-Box near the Zinc Fingers of the Human Vitamin D Receptor Is Required for Heterodimeric DNA Binding and Transactivation by Hsieh, J.C., Jurutka, P.W., Selznick, S.H., Reeder, M.C., Haussler, C.A., Whitfield, G.K., Haussler, M.R.

“…The T-box mediates binding of retinoid X receptor (RXR) homodimers to DNA while the P- and D-box in the zinc fingers of steroid hormone receptors play roles in…”
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Phosphorylation of the human 1,25-dihydroxyvitamin D3 receptor by cAMP-dependent protein kinase, in vitro, and in transfected COS-7 cells by Jurutka, P W, Hsieh, J C, Haussler, M R

“…We report that the human 1,25-dihydroxyvitamin D3 receptor is an efficient substrate for cAMP-dependent protein kinase, in vitro. This phosphorylation reaction…”
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