Implantable functional gastrointestinal neurostimulation

Implantable functional gastrointestinal neurostimulation

Neural Gastrointestinal Electrical Stimulation (NGES) is a new microprocessor-based method for invoking gastric or colonic contractions by generating multi-channel, high energy, high frequency waveforms. It has been shown that when applied to the lower stomach, NGES offers the possibility for enhanc...

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Bibliographic Details
Published in:2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society Vol. 2009; pp. 4615 - 4618
Main Authors: Jurkov, A.S., Arriagada, A., Mintchev, M.P.
Format: Conference Proceeding Journal Article
Language:English
Published: United States IEEE 01-01-2009
Subjects:
Animals
Colon
Dogs
Electric Stimulation - instrumentation
Electric Stimulation - methods
Electrical stimulation
Equipment Design
Frequency
Gastric Emptying
Gastrointestinal Diseases - therapy
Gastrointestinal tract
Gastroparesis - therapy
Humans
Life estimation
Liquids
Prostheses and Implants
Stomach
Testing
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Summary:Neural Gastrointestinal Electrical Stimulation (NGES) is a new microprocessor-based method for invoking gastric or colonic contractions by generating multi-channel, high energy, high frequency waveforms. It has been shown that when applied to the lower stomach, NGES offers the possibility for enhancing propulsive peristalsis for the treatment of gastric motor dysfunctions, or for producing retrograde peristalsis for the treatment of obesity. When applied to the colon, NGES can be utilized either for propulsive control in severe constipation or for invoked retrograde contractility. This paper briefly discusses the implementation of an implantable neurostimulator and summarizes the performance of the NGES technique in acute tests on experimental animals and humans, and in chronic tests on animals. These experimental tests indicate that NGES is successful in accelerating gastric emptying of both liquids and solids, and in producing strong, externally-controlled, retrograde contractions.
ISSN:1094-687X
1557-170X
1558-4615
DOI:10.1109/IEMBS.2009.5332682