Search Results - "Juris, Stephen J."

A Phenylalanine Clamp Catalyzes Protein Translocation through the Anthrax Toxin Pore by Krantz, Bryan A., Melnyk, Roman A., Zhang, Sen, Juris, Stephen J., Lacy, D. Borden, Wu, Zhengyan, Finkelstein, Alan, Collier, R. John

“…The protective antigen component of anthrax toxin forms a homoheptameric pore in the endosomal membrane, creating a narrow passageway for the enzymatic…”
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Evidence for a proton-protein symport mechanism in the anthrax toxin channel by Basilio, Daniel, Juris, Stephen J, Collier, R John, Finkelstein, Alan

“…The toxin produced by Bacillus anthracis, the causative agent of anthrax, is composed of three proteins: a translocase heptameric channel, (PA(63))(7), formed…”
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Binding Stoichiometry and Kinetics of the Interaction of a Human Anthrax Toxin Receptor, CMG2, with Protective Antigen by Wigelsworth, Darran J., Krantz, Bryan A., Christensen, Kenneth A., Lacy, D. Borden, Juris, Stephen J., Collier, R. John

“…The protective antigen (PA) moiety of anthrax toxin binds to cellular receptors and mediates entry of the two enzymatic moieties of the toxin into the cytosol…”
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A Distinctive Role for the Yersinia Protein Kinase: Actin Binding, Kinase Activation, and Cytoskeleton Disruption by Juris, Stephen J., Rudolph, Amy E., Huddler, Don, Orth, Kim, Dixon, Jack E.

“…The bacterial pathogens of the genus Yersinia deliver several virulence factors into target cells using a type III secretion system. We demonstrate that…”
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Interdisciplinary undergraduate education: water as life, death, and power and the certificate in global health disparities by Mueller, Anja, Dr, Juris, Stephen J, PhD, Willermet, Cathy, PhD, Drake, Eron, EdD, Upadhaya, Samik, MS, Chhetri, Pratik, BS

“…Abstract Background Central Michigan University's student chapter of Universities Allied for Essential Medicines organised a conference on global health…”
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Cross-Linked Forms of the Isolated N-Terminal Domain of the Lethal Factor Are Potent Inhibitors of Anthrax Toxin by Juris, Stephen J, Melnyk, Roman A, Bolcome, Robert E. III, Chan, Joanne, Collier, R. John

“…The proteins that comprise anthrax toxin self-assemble at the mammalian cell surface into a series of toxic complexes, each containing a heptameric form of…”
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Assessing Interdisciplinary Learning and Student Activism in a Water Issues Course by Juris, Stephen J., Mueller, Anja, Willermet, Cathy, Drake, Eron, Upadhaya, Samik, Chhetri, Pratik

“…In response to a request from a campus student organization, faculty from three fields came together to develop and teach an integrated interdisciplinary…”
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Dichotomous effects of isomeric secondary amines containing an aromatic nitrile and nitro group on human aortic smooth muscle cells via inhibition of cystathionine-γ-lyase by Ji, Yajing, Bowersock, Austin, Badour, Alec R., Vij, Neeraj, Juris, Stephen J., Ash, David E., Mohanty, Dillip K.

“…Excessive proliferation of vascular smooth muscle cells (SMC) is an important contributor to the progression of atherosclerosis. Inhibition of proliferation…”
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Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry by Juris, Stephen J., Shah, Kavita, Shokat, Kevan, Dixon, Jack E., Vacratsis, Panayiotis O.

“…Yersinia encodes a protein kinase, YpkA, which disrupts the actin cytoskeleton. Using an approach termed chemical genetics, we identified a 36-kDa substrate…”
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Yersinia effectors target mammalian signalling pathways by Juris, Stephen J., Shao, Feng, Dixon, Jack E.

“…Summary Animals have an immune system to fight off challenges from both viruses and bacteria. The first line of defence is innate immunity, which is composed…”
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Effect of 2-Fluorohistidine Labeling of the Anthrax Protective Antigen on Stability, Pore Formation, and Translocation by Wimalasena, D. Shyamali, Cramer, John C, Janowiak, Blythe E, Juris, Stephen J, Melnyk, Roman A, Anderson, D. Eric, Kirk, Kenneth L, Collier, R. John, Bann, James G

“…The action of anthrax toxin relies in part upon the ability of the protective antigen (PA) moiety to form a heptameric pore in the endosomal membrane,…”
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Water as life, death, and power: Building an integrated interdisciplinary course combining perspectives from anthropology, biology, and chemistry by Willermet, Cathy, Mueller, Anja, Juris, Stephen J, Drake, Eron, Upadhaya, Samik, Chhetri, Pratik

“…In response to a request from a campus student organization, faculty from three fields came together to develop and teach an integrated interdisciplinary…”
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The case for developing consensus standards for research in microbial pathogenesis: Bacillus anthracis toxins as an example by Hughes, Molly A, Burns, Drusilla L, Juris, Stephen J, Tang, Wei-Jen, Clement, Kristin H, Eaton, Linda J, Kelly-Cirino, Cassandra D, McKee, Marian L, Powell, Bradford S, Bishop, Brian L, Rudge, Thomas L, Shine, Nancy, Verma, Anita, Willis, Melissa Swope, Morse, Stephen A

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Evidence for a Proton–Protein Symport Mechanism in the Anthrax Toxin Channel by Basilio, Daniel, Juris, Stephen J., Collier, R. John, Finkelstein, Alan

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Evidence for Proton-Coupled Protein Transport through the Anthrax Toxin Channel by Basilio, Daniel, Juris, Stephen J., Collier, R. John, Finkelstein, Alan

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Evidence for a ProtonaProtein Symport Mechanism in the Anthrax Toxin Channel by Basilio, Daniel, Juris, Stephen J, Collier, RJohn, Finkelstein, Alan

“…The toxin produced by Bacillus anthracis, the causative agent of anthrax, is composed of three proteins: a translocase heptameric channel, (PA sub(63)) sub(7),…”
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Corrigendum to “Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry” [FEBS Lett. 580 (2006) 179–183] by Juris, Stephen J., Shah, Kavita, Shokat, Kevan, Dixon, Jack E., Vacratsis, Panayiotis O.

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Effect of 2-Fluorohistidine Labeling of the Anthrax Protective Antigen on Stability, Pore Formation, and Translocation by Wimalasena, DShyamali, Cramer, John C, Janowiak, Blythe E, Juris, Stephen J, Melnyk, Roman A, Anderson, DEric, Kirk, Kenneth L, Collier, RJohn, Bann, James G

“…The action of anthrax toxin relies in part upon the ability of the protective antigen (PA) moiety to form a heptameric pore in the endosomal membrane,…”
Get full text