Search Results - "Jurgielewicz, Brian"

Kinetics and Specificity of HEK293T Extracellular Vesicle Uptake using Imaging Flow Cytometry by Jurgielewicz, Brian J., Yao, Yao, Stice, Steven L.

“…Extracellular vesicles (EVs) are nanosized lipid bilayer-bound vesicles that are naturally secreted from most cell types as a communication mechanism to…”
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Human Neural Stem Cell Extracellular Vesicles Improve Recovery in a Porcine Model of Ischemic Stroke by Webb, Robin L, Kaiser, Erin E, Jurgielewicz, Brian J, Spellicy, Samantha, Scoville, Shelley L, Thompson, Tyler A, Swetenburg, Raymond L, Hess, David C, West, Franklin D, Stice, Steven L

“…BACKGROUND AND PURPOSE—Recent work from our group suggests that human neural stem cell–derived extracellular vesicle (NSC EV) treatment improves both tissue…”
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Exploring the predictive value of lesion topology on motor function outcomes in a porcine ischemic stroke model by Scheulin, Kelly M., Jurgielewicz, Brian J., Spellicy, Samantha E., Waters, Elizabeth S., Baker, Emily W., Kinder, Holly A., Simchick, Gregory A., Sneed, Sydney E., Grimes, Janet A., Zhao, Qun, Stice, Steven L., West, Franklin D.

“…Harnessing the maximum diagnostic potential of magnetic resonance imaging (MRI) by including stroke lesion location in relation to specific structures that are…”
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An integrative multivariate approach for predicting functional recovery using magnetic resonance imaging parameters in a translational pig ischemic stroke model by Kaiser, Erin, Poythress, J, Scheulin, Kelly, Jurgielewicz, Brian, Lazar, Nicole, Park, Cheolwoo, Stice, Steven, Ahn, Jeongyoun, West, Franklin

“…Magnetic resonance imaging (MRI) is a clinically relevant, real-time imaging modality that is frequently utilized to assess stroke type and severity. However,…”
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Neural Stem Cell Extracellular Vesicles Disrupt Midline Shift Predictive Outcomes in Porcine Ischemic Stroke Model by Spellicy, Samantha E., Kaiser, Erin E., Bowler, Michael M., Jurgielewicz, Brian J., Webb, Robin L., West, Franklin D., Stice, Steven L.

“…Magnetic resonance imaging (MRI) is a clinically relevant non-invasive imaging tool commonly utilized to assess stroke progression in real time. This study…”
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Semi-Automated Cell and Tissue Analyses Reveal Regionally Specific Morphological Alterations of Immune and Neural Cells in a Porcine Middle Cerebral Artery Occlusion Model of Stroke by Spellicy, Samantha E, Scheulin, Kelly M, Baker, Emily W, Jurgielewicz, Brian J, Kinder, Holly A, Waters, Elizabeth S, Grimes, Janet A, Stice, Steven L, West, Franklin D

“…Histopathological analysis of cellular changes in the stroked brain provides critical information pertaining to inflammation, cell death, glial scarring, and…”
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Magnetic Resonance Imaging and Gait Analysis Indicate Similar Outcomes Between Yucatan and Landrace Porcine Ischemic Stroke Models by Sneed, Sydney E, Scheulin, Kelly M, Kaiser, Erin E, Fagan, Madison M, Jurgielewicz, Brian J, Waters, Elizabeth S, Spellicy, Samantha E, Duberstein, Kylee J, Platt, Simon R, Baker, Emily W, Stice, Steven L, Kinder, Holly A, West, Franklin D

“…The Stroke Therapy Academic Industry Roundtable (STAIR) has recommended that novel therapeutics be tested in a large animal model with similar anatomy and…”
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Therapeutic Potential of Nucleic Acids when Combined with Extracellular Vesicles by Jurgielewicz, Brian, Stice, Steven, Yao, Yao

“…Extracellular vesicles (EVs), endogenous nanocarriers of proteins, lipids, and genetic material, have been harnessed as intrinsic delivery vectors for nucleic…”
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Abstract TP107: Midline Shift Predicts Functional Outcomes in Porcine Ischemic Stroke Model by Spellicy, Samantha, Kaiser, Erin, Bowler, Michael, Jurgielewicz, Brian, Webb, Robin, West, Franklin, Stice, Steven

“…Abstract only In this study, we sought to identify acute MRI parameters which are predictive of long-term functional outcomes as well as assess the effects of…”
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Abstract P763: A Precision Medicine Approach to Intracerebral Stem Cell Transplantation Utilizing Lesion Topology in a Porcine Model of Ischemic Stroke by Scheulin, Kelly M, Jurgielewicz, Brian J, Saini, Monika, Spellicy, Samantha E, Waters, Elizabeth S, Baker, Emily W, Kinder, Holly A, Simchick, Gregory A, Sneed, Sydney E, Zhao, Qun, Stice, Steven L, West, Franklin D

“…Despite the devastating global impact of ischemic stroke, there are few Food and Drug Administration (FDA) approved treatments, none of which are capable of…”
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Extracellular Vesicles as Therapeutic Delivery Vectors for Neurological Disorders by Jurgielewicz, Brian Joseph

“…Extracellular vesicles (EVs) are nanosized (40-1,000nm in diameter) lipid bound vesicles released from most cell types responsible for delivery of functional…”
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Human neural stem cell extracellular vesicles improve recovery in a porcine model of ischemic stroke by Webb, Robin, Kaiser, Erin E, Jurgielewicz, Brian J, Spellicy, Samantha, Scoville, Shelley, Thompson, Tyler, Swetenburg, Raymond L, West, Franklin, Stice, Steven

“…Background: Recent work from our group suggests that human neural stem cell-derived extracellular vesicle (NSC EV) treatment improves both tissue and…”
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