Search Results - "Jurgenson, Tuuli"
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The role of depression and antidepressant treatment in antihypertensive medication adherence and persistence: Utilising electronic health record data
Published in Journal of psychiatric research (01-12-2023)“…Higher blood pressure levels in patients with depression may be associated with lower adherence to antihypertensive medications (AHMs). Here, we use electronic…”
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Long-term mortality following SARS-CoV-2 infection: A national cohort study from Estonia
Published in The Lancet regional health. Europe (01-07-2022)“…The objective of this study was to describe 12-month mortality following SARS-CoV-2 infection compared with a reference population with no history of…”
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Omics-informed CNV calls reduce false-positive rates and improve power for CNV-trait associations
Published in HGG advances (13-10-2022)“…Copy-number variations (CNV) are believed to play an important role in a wide range of complex traits, but discovering such associations remains challenging…”
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Stroke genetics informs drug discovery and risk prediction across ancestries
Published in Nature (London) (01-11-2022)“…Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of…”
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NOVEL LOCI FOR ANTIDEPRESSANT RESPONSE IDENTIFIED FROM GENOME-WIDE ASSOCIATION STUDIES AND MULTI-TRAIT META-ANALYSES
Published in European neuropsychopharmacology (01-10-2023)“…Antidepressants exhibit a large variation in efficacy in treated individuals, and increasing evidence suggests that individual genetics contribute to…”
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TU34. ASSOCIATION BETWEEN DEPRESSION DIAGNOSIS, POLYGENIC RISK FOR DEPRESSION AND ANTIHYPERTENSIVE MEDICATION NON-PERSISTENCE
Published in European neuropsychopharmacology (01-10-2021)Get full text
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Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy
Published in American journal of human genetics (01-10-2020)“…Hypersensitivity reactions to drugs are often unpredictable and can be life threatening, underscoring a need for understanding their underlying mechanisms and…”
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Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine
Published in Science advances (03-09-2021)“…Interindividual variability in drug response constitutes a major concern in pharmacotherapy. While polymorphisms in genes involved in drug disposition have…”
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Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure, and Dementia
Published in JAMA network open (01-05-2024)“…Vascular disease is a treatable contributor to dementia risk, but the role of specific markers remains unclear, making prevention strategies uncertain. To…”
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