Search Results - "Juranic, Nenad"

O-assisted dynamic metabolomics for individualized diagnostics and treatment of human diseases by Nemutlu, Emirhan, Zhang, Song, Juranic, Nenad O, Terzic, Andre, Macura, Slobodan, Dzeja, Petras

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Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4 by Benirschke, Robert C., Thompson, James R., Nominé, Yves, Wasielewski, Emeric, Juranić, Nenad, Macura, Slobodan, Hatakeyama, Shigetsugu, Nakayama, Keiichi I., Botuyan, Maria Victoria, Mer, Georges

“…Human E4B, also called UFD2a, is a U box-containing protein that functions as an E3 ubiquitin ligase and an E4 polyubiquitin chain elongation factor. E4B is…”
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Calmodulin Wraps around Its Binding Domain in the Plasma Membrane Ca²⁺ Pump Anchored by a Novel 18-1 Motif by Juranic, Nenad, Atanasova, Elena, Filoteo, Adelaida G, Macura, Slobodan, Prendergast, Franklyn G, Penniston, John T, Strehler, Emanuel E

“…Using solution NMR spectroscopy, we obtained the structure of Ca²⁺-calmodulin (holoCaM) in complex with peptide C28 from the binding domain of the plasma…”
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18O-assisted dynamic metabolomics for individualized diagnostics and treatment of human diseases by Nemutlu, Emirhan, Zhang, Song, Juranic, Nenad O, Terzic, Andre, Macura, Slobodan, Dzeja, Petras

“…Technological innovations and translation of basic discoveries to clinical practice drive advances in medicine. Today's innovative technologies enable…”
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Halothane binds to druggable sites in the [Ca2+]4-calmodulin (CaM) complex, but does not inhibit [Ca2+]4-CaM activation of kinase by Juranić Nenad O., Jones Keith A., Penheiter Alan R., Hock Thomas J., Streiff John H.

“…The mechanism(s) of volatile anesthetics (VA) are poorly understood. We used high resolution NMR spectroscopy to determine the structure of the…”
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Dynamic phosphometabolomic profiling of human tissues and transgenic models by 18O-assisted ³¹P NMR and mass spectrometry by Nemutlu, Emirhan, Zhang, Song, Gupta, Anu, Juranic, Nenad O, Macura, Slobodan I, Terzic, Andre, Jahangir, Arshad, Dzeja, Petras

“…Next-generation screening of disease-related metabolomic phenotypes requires monitoring of both metabolite levels and turnover rates. Stable isotope…”
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Directly observed hydrogen bonds at calcium-binding-sites of calmodulin in solution relate to affinity of the calcium-binding by Juranić, Nenad, Atanasova, Elena, Macura, Slobodan, Prendergast, Franklyn G.

“…Molecular tuning to calcium-binding in the EF-hand motif of holo-calmodulin was studied in solution by NMR h3 J NC′ H-bond couplings. In the N-terminus lobe of…”
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Solvent‐induced differentiation of protein backbone hydrogen bonds in calmodulin by Juranić, Nenad, Atanasova, Elena, Streiff, John H., Macura, Slobodan, Prendergast, Franklyn G.

“…In apo and holoCaM, almost half of the hydrogen bonds (H‐bonds) at the protein backbone expected from the corresponding NMR or X‐ray structures were not…”
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Solvated Electrons in Organic Chemistry Laboratory by Ilich, Predrag-Peter, McCormick, Kathleen R, Atkins, Adam D, Mell, Geoffrey J, Flaherty, Timothy J, Bruck, Martin J, Goodrich, Heather A, Hefel, Aaron L, Juranić, Nenad, Seleem, Suzanne

“…A novel experiment is described in which solvated electrons in liquid ammonia reduce a benzyl alcohol carbon without affecting the aromatic ring. The reductive…”
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Saturation transfer difference nuclear magnetic resonance spectroscopy as a method for screening proteins for anesthetic binding by Streiff, John H, Juranic, Nenad O, Macura, Slobodan I, Warner, David O, Jones, Keith A, Perkins, William J

“…The effects of anesthetics on cellular function may result from direct interactions between anesthetic molecules and proteins. These interactions have a low…”
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Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II) by Todorović, Tamara R., Bacchi, Alessia, Juranić, Nenad O., Sladić, Dušan M., Pelizzi, Giancarlo, Božić, Tatjana T., Filipović, Nenad R., Anđelković, Katarina K.

“…A ligand 2-quinolinecarboxaldehyde selenosemicarbazone (Hqasesc) was synthesized and coordinated with Zn(II), Cd(II) and Ni(II). Single crystal X-ray analysis…”
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One-Bond 15N13C′ Nuclear Spin-Spin Coupling in N-Methylacetamide: a Model for Hydrogen-Bonded Peptides by Ilich, Predrag, Juranić, Nenad

“…New insight into hydrogen bonds: The authors present a new approach to the analysis of the polypeptide and polynucleotide secondary structures that is based on…”
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Prediction of Volatile Anesthetic Binding Sites in Proteins by Streiff, John H., Allen, Thomas W., Atanasova, Elena, Juranic, Nenad, Macura, Slobodan, Penheiter, Alan R., Jones, Keith A.

“…Computational methods designed to predict and visualize ligand protein binding interactions were used to characterize volatile anesthetic (VA) binding sites…”
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Steroid template associated peptides: design, synthesis and 2D NMR characterization of a novel protected 18-Phe,19-Gly-containing steroidal compound by Bjelaković, Mira S., Krstić, Natalija M., Juranić, Nenad, Dabović, Milan M., Gojković, Svetislav V., Kessler, Martin, Kalvoda, Jaroslav, Pavlović, Vladimir D.

“…We report herein the synthesis of a novel modified steroid with two rigidly positioned amino acids in C- and N-protected forms (Gly–O t Bu and N-Fmoc– l-Phe)…”
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Synthesis, NMR, DFT and antimicrobial studies of Zn(II) complexes with N-benzyloxycarbonyl-S-alanine by DRAGANA M. MITIC, DJENANA U. MIODRAGOVIC, DUSAN M. SLADIC, ZELJKO J. VITNIK, ZORAN M. MIODRAGOVIC, KATARINA K. ANDJELKOVIC, MILANKA Dj. RADULOVIC, NENAD O. JURANIC

“…In this study, the first complexes of Zn(II) with the N-benzyl-oxycarbonyl-S-alaninato ligand (N-Boc-S-ala) were synthesized. The new complexes were…”
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Electron Delocalization Mediates the Metal-Dependent Capacity for CH/π Interactions of Acetylacetonato Chelates by Milčič, Miloš K, Medaković, Vesna B, Sredojević, Dušan N, Juranić, Nenad O, Zarić, Snežana D

“…CH/π interactions between the coordinated acetylacetonato ligand and phenyl rings were analyzed in the crystal structures from the Cambridge Structural…”
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Cellular Energetics in the Preconditioned State by Pucar, Darko, Dzeja, Petras P., Bast, Peter, Juranic, Nenad, Macura, Slobodan, Terzic, Andre

“…Cell survival is critically dependent on the preservation of cellular bioenergetics. However, the metabolic mechanisms that confer resistance to injury are…”
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Full matrix Analysis of Cross-relaxation Fails in Fractionally Deuterated Molecules by Zolnai, Z, Juranić, N, Macura, S

“…We have analyzed cross-relaxation in fractionally deuterated molecules and showed that the full matrix analysis fails except when the dilution is extreme. This…”
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Three-Dimensional Structure of the Water-Insoluble Protein Crambin in Dodecylphosphocholine Micelles and Its Minimal Solvent-Exposed Surface by Ahn, Hee-Chul, Juranić, Nenad, Macura, Slobodan, Markley, John L

“…We chose crambin, a hydrophobic and water-insoluble protein originally isolated from the seeds of the plant Crambe abyssinica, as a model for NMR…”
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Two-dimensional exchange spectroscopy revisited: Accounting for the number of participating spins by Juranić Nenad, Zolnai Zsolt, Macura Slobodan

“…The magnetization exchange between two groups of equivalent spins each having different populations and overall relaxation rates has been analyzed. The results…”
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