Search Results - "Juranek, I."

On infusion of high-dose ascorbate in treating cancer: Is it time for N-acetylcysteine pretreatment to enhance susceptibility and to lower side effects? by Valachová, K., Juránek, I., Rapta, P., Valent, I., Šoltés, L.

“…Ascorbate administered intravenously gives a high plasma concentration of this drug. Clinical trials with pancreatic carcinoma patients revealed their…”
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Antioxidants in treating pathologies involving oxidative damage: an update on medicinal chemistry and biological activity of stobadine and related pyridoindoles by Juranek, I, Horakova, L, Rackova, L, Stefek, M

“…Pathologies involving oxidative stress are indicative of malfunction of endogenous antioxidant capacity. Numerous efforts were made to design and synthesize…”
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Hyaluronan peroxidation is required for normal synovial function: An hypothesis by Juranek, I, Stern, R, Šoltes, L

“…Abstract Despite widespread use of antioxidants, reactive oxygen species have important functions in normal tissues. Herein, we present an example of a…”
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Improved tissue integrity after alginate treatment in rat spinal cord injury: evidence from ex vivo diffusion tensor imaging by Baciak, Ladislav, Melichercik, Lubomir, Mate, Veronika, Murgoci, Adriana-Natalia, Smolek, Tomas, Juranek, Ivo, Gogola, Daniel, Hudakova, Nikola, Cizek, Milan, Cizkova, Dasa

“…Diffusion tensor imaging (DTI) is a magnetic resonance imaging technique used to characterize fibrous structures such as white matter in the central nervous…”
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Meet interesting abbreviations in clinical mass spectrometry: from compound classification by REIMS to multimodal and mass spectrometry imaging (MSI) by Luptáková, D, Pluháček, T, Palyzová, A, Přichystal, J, Balog, J, Lemr, K, Juránek, I, Havlíček, V

“…This feature article discusses two modern mass spectrometry abbreviations in their clinical applications. Rapid evaporative ionization mass spectrometry…”
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Lipid peroxidation during acute stress by Kovács, P, Juránek, I, Stankovicová, T, Svec, P

“…Lipid peroxidation (LPO) is one of the main events induced by oxidative stress. The aim of our study was to investigate the influence of 30 min…”
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Evidence for the participation of glutamate in reflexes involving afferent, substance P‐containing nerve fibres in the rat by Juránek, Ivo, Lembeck, Fred

“…1 Responses mediated, either peripherally or centrally, by substance P‐containing primary afferent C‐fibres were investigated in the rat following impairment…”
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Afferent C-fibres release substance P and glutamate by Juránek, I, Lembeck, F

“…Capsaicin is currently used as a specific pharmacological tool for investigation of functions of primary afferent C-fibres. Their peripheral terminals play an…”
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Effect of illuminated nifedipine, a potent antioxidant, on intestinal and vascular smooth muscles by Bauer, V., Rekalov, V.V., Juranek, I., Gergel, D., Bohov, P.

“…1 The effects of nifedipine (Nif) and its illuminated nitroso product nitrosopine (NTP) were investigated on lipid peroxidation, KC1 elevated smooth muscle…”
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Effect of trapencaine and some of its derivatives on gastric wall mucus in stressed rats by Nosálová, V, Juránek, I, Babulová, A

“…The effect of selected carbanilates on the rat gastric mucus was tested after oral administration. The compounds K 1905 and K 2002 were found to increase…”
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On augmentation of adenosine-mediated negative dromotropic effect by K+ released during myocardial ischemia by Juránek, I

“…The present study was designed to investigate mechanisms of adenosine (ADO)-mediated prolongation of conductivity through the atrioventricular (AV) node during…”
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Influence of acute stress on lipid peroxidation in vivo by Juránek, I, Bauer, V, Horáková, L

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Antioxidative activity of homoisoflavonoids from Muscari racemosum and Dracena cinnabari by Juránek, I, Suchý, V, Stará, D, Maśterova, I, Grancaiová, Z

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Pro-oxidative effect of peroxynitrite regarding biological systems: a special focus on high-molar-mass hyaluronan degradation by Hrabarova, Eva, Juranek, Ivo, Soltes, Ladislav

“…Current understanding on the role of peroxynitrite in etiology and pathogenesis of some human diseases, such as cardio-vascular diseases, stroke, cancer,…”
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Effects of reactive oxygen species on smooth muscles their innervation, epithelium and endothelium by Bauer, V., Matyás, Sˇ., Pucovský, V., Gergel, D., Juránek, I.

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Effect of oxidative stress on (3H)N-methylscopolamine binding and production of thiobarbituric acid reactive substances in rat cerebral cortex membranes by Kvaltínová, Z, Juránek, I, Machová, J, Stolc, S

“…We investigated the effect of lipid peroxidation, in vitro induced by H2O2 or FeSO4 and ascorbic acid, on binding properties of muscarinic receptors in rat…”
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Short cerebral ischemia and subsequent reperfusion and treatment with stobadine by Horakova, L, Ondrejickova, O, Uraz, V, Lukovic, L, Juranek, I

“…Lipid peroxidation and activities of antioxidative enzymes were studied in the brain cortex after short (15 min) cerebral ischemia and reperfusion (10 min) in…”
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Ascorbate and Cu(II)-induced oxidative degradation of high-molar-mass hyaluronan. Pro- and antioxidative effects of some thiols by Valachova, Katarina, Hrabarova, Eva, Drafi, Frantisek, Juranek, Ivo, Bauerova, Katarina, Priesolova, Elena, Nagy, Milan, Soltes, Ladislav

“…This study presents the results of antioxidative and pro-oxidative efficacy of cysteamine and D-penicillamine (D-pen) in comparison to L-glutathione (L-GSH) on…”
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Carnosine inhibits degradation of hyaluronan induced by free radical processes in vitro and improves the redox imbalance in adjuvant arthritis in vivo by Drafi, Frantisek, Bauerova, Katarina, Valachova, Katarina, Ponist, Silvester, Mihalova, Danica, Juranek, Ivo, Boldyrev, Alexander, Hrabarova, Eva, Soltes, Ladislav

“…New ways of supplementary or combinatory therapy of rheumatoid arthritis (RA) are of great importance. The aim is to find an additive to classical RA therapy…”
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Effect of stobadine on lipid peroxidation in brain and heart after ischemia and reperfusion of the brain by Ondrejičková, O., Horáková, L., Juránek, I., Ziegelhoeffer, A., Štolc, S.

“…Stobadine (ST), a novel drug with pyridoindol structure, was recently found to prevent reperfusion injury in rat brain. The aim of the present study was to…”
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