Search Results - "Juránek, Ivo"

Preparation and Physicochemical Characterization of Gelatin-Aldehyde Derivatives by El-Meligy, Mahmoud Atya, Valachová, Katarína, Juránek, Ivo, Tamer, Tamer M, Šoltés, Ladislav

“…The present study aimed at preparing novel free-radical scavenging and water-soluble compounds derived from gelatin. Specifically, gelatin−syringaldehyde,…”
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Hypoxic-Ischemic Insult Alters Polyamine and Neurotransmitter Abundance in the Specific Neonatal Rat Brain Subregions by Mácha, Hynek, Luptáková, Dominika, Juránek, Ivo, Andrén, Per E., Havlíček, Vladimír

“…Neonatal hypoxic-ischemic (HI) brain insult is a major cause of neonatal mortality and morbidity. To assess the underlying pathological mechanisms, we mapped…”
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Enhanced Anti-Inflammatory Effect of the Combination of Lactiplantibacillus plantarum LS/07 with Methotrexate Compared to Their Monotherapies Studied in Experimental Arthritis by Pružinská, Katarína, Slovák, Lukáš, Dráfi, František, Poništ, Silvester, Juránek, Ivo, Chrastina, Martin, Švík, Karol, Strojný, Ladislav, Ambro, Ľuboš, Bauerová, Katarína

“…The gut microbiome (GM) of rheumatic arthritis (RA) patients is often altered in composition and function. Moreover, methotrexate (MTX), one of the most…”
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Influence of tiopronin, captopril and levamisole therapeutics on the oxidative degradation of hyaluronan by Valachová, Katarína, Baňasová, Mária, Topoľská, Dominika, Sasinková, Vlasta, Juránek, Ivo, Collins, Maurice N., Šoltés, Ladislav

“…•Captopril and tiopronin are effective donors of H and electrons.•Captopril and tiopronin retard HA oxidative degradation.•Levamisole drug is ineffective and…”
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Biological importance of reactive oxygen species in relation to difficulties of treating pathologies involving oxidative stress by exogenous antioxidants by Juránek, Ivo, Nikitovic, Dragana, Kouretas, Dimitrios, Hayes, A. Wallace, Tsatsakis, Aristidis M.

“…[Display omitted] •Reactive oxygen species (ROS) are deleterious to essential biomacromolecules.•Yet, starting from life origin and evolution, ROS are involved…”
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Rare causes of respiratory insufficiency in newborns by Brucknerová, J, Babala, J, Ujházy, E, Mach, M, Juránek, I, Brucknerová, I

“…Congenital lung masses (CLM) the rare group of causes of acute respiratory insufficiency (RI) in newborns include congenital airway pulmonary malformation…”
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Cerebral hypoxia–ischemia: Focus on the use of magnetic resonance imaging and spectroscopy in research on animals by JURANEK, Ivo, BACIAK, Ladislav

“…Cerebral hypoxic–ischemic injury represents a serious health problem and is the third leading cause of mortality in developed countries. Early diagnosis of…”
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Free-Radical Degradation of High-Molar-Mass Hyaluronan Induced by Ascorbate plus Cupric Ions: Evaluation of Antioxidative Effect of Cysteine-Derived Compounds by Hrabárová, Eva, Valachová, Katarína, Juránek, Ivo, Šoltés, Ladislav

“…Based on our previous findings, the present study has focused on free‐radical‐mediated degradation of the synovial biopolymer hyaluronan. The degradation was…”
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Free-radical degradation of high-molecular-weight hyaluronan induced by ascorbate plus cupric ions. Testing of bucillamine and its SA981-metabolite as antioxidants by Valachová, Katarína, Hrabárová, Eva, Priesolová, Elena, Nagy, Milan, Baňasová, Mária, Juránek, Ivo, Šoltés, Ladislav

“…High-molecular-weight hyaluronan (HA) samples were exposed to free-radical chain-degradation reactions induced by ascorbate in the presence of Cu(II) ions –…”
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Effect of Bucillamine on Free-Radical-Mediated Degradation of High-Molar-Mass Hyaluronan Induced in vitro by Ascorbic Acid and Cu(II) Ions by Baňasová, Mária, Valachová, Katarína, Rychlý, Jozef, Janigová, Ivica, Csomorová, Katarína, Mendichi, Raniero, Mislovičová, Danica, Juránek, Ivo, Šoltés, Ladislav

“…The bucillamine effect on free-radical-mediated degradation of high-molar-mass hyaluronan (HA) has been elucidated. As HA fragmentation is expected to decrease…”
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Structural characterisation of thiol-modified hyaluronans by Hrabárová, Eva, Rychlý, Jozef, Sasinková, Vlasta, Valachová, Katarína, Janigová, Ivica, Csomorová, Katarína, Juránek, Ivo, Šoltés, Ladislav

“…Fourier-transform infrared spectroscopy and non-isothermal methods—chemiluminometry, differential scanning calorimetry, and differential thermogravimetry—were…”
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Assessment of motor recovery and MRI correlates in a porcine spinal cord injury model by Šulla, Igor, Bačiak, Ladislav, Juránek, Ivo, Cicholesová, Tatiana, Boldižár, Martin, Balik, Vladimír, Lukáčová, Nadežda

“…The study concentrated on behavioral and magnetic resonance imaging (MRI) characteristics in a porcine spinal cord injury model. Six adult minipigs weighing…”
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Free-radical degradation of high-molar-mass hyaluronan induced by Weissberger's oxidative system: potential antioxidative effect of bucillamine by Banasova, Maria, Sasinkova, Vlasta, Mendichi, Raniero, Perecko, Tomas, Valachova, Katarina, Juranek, Ivo, Soltes, Ladislav

“…Hyaluronan (HA), one of the main components of extracellular matrix, is a glycosaminoglycan composed of repeating disaccharide units of N-acetyl-d-glucosamine…”
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Aurothiomalate as Preventive and Chain-Breaking Antioxidant in Radical Degradation of High-Molar-Mass Hyaluronan by Valachová, Katarína, Vargová, Andrea, Rapta, Peter, Hrabárová, Eva, Dráfi, František, Bauerová, Katarína, Juránek, Ivo, Šoltés, Ladislav

“…The potential anti‐ or pro‐oxidative effects of a disease‐modifying antirheumatic drug, aurothiomalate, to protect high‐molar‐mass hyaluronan against radical…”
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Ascorbate and Cu(II)-induced oxidative degradation of high-molar-mass hyaluronan. Pro- and antioxidative effects of some thiols by Valachova, Katarina, Hrabarova, Eva, Drafi, Frantisek, Juranek, Ivo, Bauerova, Katarina, Priesolova, Elena, Nagy, Milan, Soltes, Ladislav

“…This study presents the results of antioxidative and pro-oxidative efficacy of cysteamine and D-penicillamine (D-pen) in comparison to L-glutathione (L-GSH) on…”
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Carnosine inhibits degradation of hyaluronan induced by free radical processes in vitro and improves the redox imbalance in adjuvant arthritis in vivo by Drafi, Frantisek, Bauerova, Katarina, Valachova, Katarina, Ponist, Silvester, Mihalova, Danica, Juranek, Ivo, Boldyrev, Alexander, Hrabarova, Eva, Soltes, Ladislav

“…New ways of supplementary or combinatory therapy of rheumatoid arthritis (RA) are of great importance. The aim is to find an additive to classical RA therapy…”
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Membrane depolarization and aberrant lipid distributions in the neonatal rat brain following hypoxic-ischaemic insult by Luptakova, Dominika, Baciak, Ladislav, Pluhacek, Tomas, Skriba, Anton, Sediva, Blanka, Havlicek, Vladimir, Juranek, Ivo

“…Neonatal hypoxic-ischaemic (HI) encephalopathy is among the most serious complications in neonatology. In the present study, we studied the immediate (0 hour),…”
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Hinokitiol, a Selective Inhibitor of the Platelet-Type Isozyme of Arachidonate 12-Lipoxygenase by Suzuki, Hiroshi, Ueda, Tetsuji, Juránek, Ivo, Yamamoto, Shozo, Katoh, Takahiro, Node, Manabu, Suzuki, Toshiyuki

“…Hinokitiol (4-isopropyltropolone), a constituent of Japanese cypress, reversibly inhibited platelet-type 12-lipoxygenase with an IC50 of 0.1 μM, and the enzyme…”
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Anthracycline-Dependent Cardiotoxicity and Extracellular Matrix Remodeling by Nikitovic, Dragana, PhD, Juranek, Ivo, MD, PhD, Wilks, Martin F., MD, PhD, Tzardi, Maria, MD, PhD, Tsatsakis, Aristidis, PhD, Tzanakakis, George N., MD, PhD

“…Abstract The mechanisms of anthracycline-dependent cardiotoxicity have been studied widely, with the suggested principal mechanism of anthracycline damage…”
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Enhanced Anti-Inflammatory Effect of the Combination of ILactiplantibacillus plantarum/I LS/07 with Methotrexate Compared to Their Monotherapies Studied in Experimental Arthritis by Pružinská, Katarína, Slovák, Lukáš, Dráfi, František, Poništ, Silvester, Juránek, Ivo, Chrastina, Ma, Švík, Karol, Strojný, Ladislav, Ambro, Ľuboš, Bauerová, Katarína

“…The gut microbiome (GM) of rheumatic arthritis (RA) patients is often altered in composition and function. Moreover, methotrexate (MTX), one of the most…”
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