Search Results - "Junqueira de Azevedo, Inacio"

Colubrid Venom Composition: An -Omics Perspective by Junqueira-de-Azevedo, Inácio L M, Campos, Pollyanna F, Ching, Ana T C, Mackessy, Stephen P

“…Snake venoms have been subjected to increasingly sensitive analyses for well over 100 years, but most research has been restricted to front-fanged snakes,…”
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Transcriptome analysis of Loxosceles laeta (Araneae, Sicariidae) spider venomous gland using expressed sequence tags by Fernandes-Pedrosa, Matheus de F, Junqueira-de-Azevedo, Inácio de L M, Gonçalves-de-Andrade, Rute M, Kobashi, Leonardo S, Almeida, Diego D, Ho, Paulo L, Tambourgi, Denise V

“…The bite of spiders belonging to the genus Loxosceles can induce a variety of clinical symptoms, including dermonecrosis, thrombosis, vascular leakage,…”
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Lachesis muta (Viperidae) cDNAs Reveal Diverging Pit Viper Molecules and Scaffolds Typical of Cobra (Elapidae) Venoms: Implications for Snake Toxin Repertoire Evolution by Junqueira-de-Azevedo, Inacio L. M, Ching, Ana T. C, Carvalho, Eneas, Faria, Fernanda, Nishiyama, Milton Y., Jr, Ho, Paulo L, Diniz, Marcelo R. V

“…Efforts to describe toxins from the two major families of venomous snakes (Viperidae and Elapidae) usually reveal proteins belonging to few structural types,…”
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Novel transcripts in the maxillary venom glands of advanced snakes by Fry, Bryan G., Scheib, Holger, Junqueira de Azevedo, Inacio de L.M., Silva, Debora Andrade, Casewell, Nicholas R.

“…Venom proteins are added to reptile venoms through duplication of a body protein gene, with the duplicate tissue-specifically expressed in the venom gland…”
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Snake venomics and venom gland transcriptomic analysis of Brazilian coral snakes, Micrurus altirostris and M. corallinus by Corrêa-Netto, Carlos, Junqueira-de-Azevedo, Inácio de L.M., Silva, Débora A., Ho, Paulo L., Leitão-de-Araújo, Moema, Alves, Maria Lúcia M., Sanz, Libia, Foguel, Débora, Zingali, Russolina Benedeta, Calvete, Juan J.

“…The venom proteomes of Micrurus altirostris and M. corallinus were analyzed by combining snake venomics and venom gland transcriptomic surveys. In both coral…”
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A Heterologous Multiepitope DNA Prime/Recombinant Protein Boost Immunisation Strategy for the Development of an Antiserum against Micrurus corallinus (Coral Snake) Venom by Ramos, Henrique Roman, Junqueira-de-Azevedo, Inácio de Loiola M, Novo, Juliana Branco, Castro, Karen, Duarte, Clara Guerra, Machado-de-Ávila, Ricardo A, Chavez-Olortegui, Carlos, Ho, Paulo Lee

“…Envenoming by coral snakes (Elapidae: Micrurus), although not abundant, represent a serious health threat in the Americas, especially because antivenoms are…”
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Transcriptomic basis for an antiserum against Micrurus corallinus (coral snake) venom by Leão, Luciana I, Ho, Paulo L, Junqueira-de-Azevedo, Inacio de L M

“…Micrurus corallinus (coral snake) is a tropical forest snake belonging to the family Elapidae. Its venom shows a high neurotoxicity associated with pre- and…”
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Transcripts involved in hemostasis: Exploring salivary complexes from Haementeria vizottoi leeches through transcriptomics, phylogenetic studies and structural features by Amorim, Adriane Michele Xavier Prado, de Oliveira, Ursula Castro, Faria, Fernanda, Pasqualoto, Kerly Fernanda Mesquita, Junqueira-de-Azevedo, Inácio de L.M., Chudzinski-Tavassi, Ana Marisa

“…Throughout evolution, parasites have adapted in order to successfully intervene in the host defense, producing specific peptides and proteins. Interestingly,…”
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Insights into the Hypertensive Effects of Tityus serrulatus Scorpion Venom: Purification of an Angiotensin-Converting Enzyme-Like Peptidase by Cajado-Carvalho, Daniela, Kuniyoshi, Alexandre Kazuo, Duzzi, Bruno, Iwai, Leo Kei, Oliveira, Úrsula Castro de, Junqueira de Azevedo, Inácio de Loiola Meirelles, Kodama, Roberto Tadashi, Portaro, Fernanda Vieira

“…The number of cases of envenomation by scorpions has grown significantly in Brazil since 2007, with the most severe cases being caused by the scorpion…”
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A New Anti-loxoscelic Serum Produced Against Recombinant Sphingomyelinase D: Results of Preclinical Trials by de Almeida, Daniel Manzoni, Fernandes-Pedrosa, Matheus de F, de Andrade, Rute M. Goncalves, Marcelino, Jose Roberto, Gondo-Higashi, Hisako, de Azevedo, Inacio de L. M. Junqueira, Ho, Paulo Lee, van den Berg, Carmen, Tambourgi, Denise V

“…Envenomation by Loxosceles species (brown spider) can lead to local dermonecrosis and to serious systemic effects. The main toxic component in the venom of…”
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Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions by de Oliveira, Ursula Castro, Nishiyama, Jr, Milton Yutaka, Dos Santos, Maria Beatriz Viana, Santos-da-Silva, Andria de Paula, Chalkidis, Hipócrates de Menezes, Souza-Imberg, Andreia, Candido, Denise Maria, Yamanouye, Norma, Dorce, Valquíria Abrão Coronado, Junqueira-de-Azevedo, Inácio de Loiola Meirelles

“…Except for the northern region, where the Amazonian black scorpion, T. obscurus, represents the predominant and most medically relevant scorpion species,…”
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Comparing morphological and secretory aspects of cephalic glands among the New World coral snakes brings novel insights on their biological roles by Oliveira, Leonardo de, Nachtigall, Pedro Gabriel, Vialla, Vincent Louis, Campos, Pollyanna F., Costa-Neves, Adriana da, Zaher, Hussam, Silva Jr, Nelson Jorge da, Grazziotin, Felipe G., Wilkinson, Mark, Junqueira-de-Azevedo, Inácio L.M.

“…Oral and other cephalic glands have been surveyed by several studies with distinct purposes. Despite the wide diversity and medical relevance of the New World…”
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An in-depth snake venom proteopeptidome characterization: Benchmarking Bothrops jararaca by Nicolau, Carolina A., Carvalho, Paulo C., Junqueira-de-Azevedo, Inácio L.M., Teixeira-Ferreira, André, Junqueira, Magno, Perales, Jonas, Neves-Ferreira, Ana Gisele C., Valente, Richard H.

“…A large-scale proteomic approach was devised to advance the understanding of venom composition. Bothrops jararaca venom was fractionated by OFFGEL followed by…”
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An integrative view of the toxic potential of Conophis lineatus (Dipsadidae: Xenodontinae), a medically relevant rear-fanged snake by Schramer, Tristan D., Rautsaw, Rhett M., Bayona-Serrano, Juan David, Nystrom, Gunnar S., West, Taylor R., Ortiz-Medina, Javier A., Sabido-Alpuche, Bianca, Meneses-Millán, Marcos, Borja, Miguel, Junqueira-de-Azevedo, Inácio L.M., Rokyta, Darin R., Parkinson, Christopher L.

“…Most traditional research on snake venoms has focused on front-fanged snake families (Viperidae, Elapidae, and Atractaspididae). However, venom is now…”
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Recombinant Production and Characterization of a New Toxin from Cryptops iheringi Centipede Venom Revealed by Proteome and Transcriptome Analysis by De Lucca Caetano, Lhiri Hanna, Nishiyama-Jr, Milton Yutaka, de Carvalho Lins Fernandes Távora, Bianca, de Oliveira, Ursula Castro, de Loiola Meirelles Junqueira-de-Azevedo, Inácio, Faquim-Mauro, Eliana L, Magalhães, Geraldo Santana

“…Among the Chilopoda class of centipede, the genus is one of the most associated with envenomation in humans in the metropolitan region of the state of São…”
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Expressed sequence tags (ESTs) from the salivary glands of the tick Amblyomma cajennense (Acari: Ixodidae) by Batista, Isabel F.C., Chudzinski-Tavassi, Ana M., Faria, Fernanda, Simons, Simone M., Barros-Batestti, Darci M., Labruna, Marcelo B., Leão, Luciana I., Ho, Paulo L., Junqueira-de-Azevedo, Inácio L.M.

“…The neotropical tick Amblyomma cajennense is a significant pest to domestic animals, the most frequently human-biting tick in South America and the main vector…”
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Phylogenetically diverse diets favor more complex venoms in North American pitvipers by Holding, Matthew L., Strickland, Jason L., Rautsaw, Rhett M., Hofmann, Erich P., Mason, Andrew J., Hogan, Michael P., Nystrom, Gunnar S., Ellsworth, Schyler A., Colston, Timothy J., Borja, Miguel, Castan˜eda-Gaytán, Gamaliel, Grünwald, Christoph I., Jones, Jason M., Freitas-de-Sousa, Luciana A., Viala, Vincent Louis, Margres, Mark J., Hingst-Zaher, Erika, Junqueira-de-Azevedo, Inácio L. M., Moura-da-Silva, Ana M., Grazziotin, Felipe G., Gibbs, H. Lisle, Rokyta, Darin R., Parkinson, Christopher L.

“…The role of natural selection in the evolution of trait complexity can be characterized by testing hypothesized links between complex forms and their functions…”
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Tracking the recruitment and evolution of snake toxins using the evolutionary context provided by the Bothrops jararaca genome by Almeida, Diego Dantas, Viala, Vincent Louis, Nachtigall, Pedro Gabriel, Broe, Michael, Gibbs, H. Lisle, de Toledo Serrano, Solange Maria, Moura-da-Silva, Ana Maria, Ho, Paulo Lee, Nishiyama, Milton Yutaka, Junqueira-de-Azevedo, Inácio L. M.

“…Venom is a key adaptive innovation in snakes, and how nonvenom genes were co-opted to become part of the toxin arsenal is a significant evolutionary question…”
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The complete mitochondrial genome of Bothrops jararaca (Reptilia, Serpentes, Viperidae) by Almeida, Diego Dantas, Kitajima, João Paulo, Nishiyama, Milton Yutaka, Condomitti, George Willian, Oliveira, Ursula Castro de, Setúbal, João Carlos, Junqueira-de-Azevedo, Inácio L. M.

“…The complete mitochondrial genome, containing 17,526 bp, was determined from the pitviper Bothrops jararaca. It is the first mitogenome for the most medically…”
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Venom-related transcripts from Bothrops jararaca tissues provide novel molecular insights into the production and evolution of snake venom by Junqueira-de-Azevedo, Inácio L M, Bastos, Carolina Mancini Val, Ho, Paulo Lee, Luna, Milene Schmidt, Yamanouye, Norma, Casewell, Nicholas R

“…Attempts to reconstruct the evolutionary history of snake toxins in the context of their co-option to the venom gland rarely account for nonvenom snake genes…”
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