Search Results - "Junna, Nella"

The genetics underlying idiopathic ventricular fibrillation: A special role for catecholaminergic polymorphic ventricular tachycardia? by Leinonen, Jaakko T., Crotti, Lia, Djupsjöbacka, Aurora, Castelletti, Silvia, Junna, Nella, Ghidoni, Alice, Tuiskula, Annukka M., Spazzolini, Carla, Dagradi, Federica, Viitasalo, Matti, Kontula, Kimmo, Kotta, Maria-Christina, Widén, Elisabeth, Swan, Heikki, Schwartz, Peter J.

“…Ventricular fibrillation (VF) is a major cause of sudden cardiac death. In some cases clinical investigations fail to identify the underlying cause and the…”
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Novel Finnish-enriched variants causing severe hypercholesterolemia and their clinical impact on coronary artery disease by Junna, Nella, Ruotsalainen, Sanni, Ripatti, Pietari, FinnGen, Ripatti, Samuli, Widén, Elisabeth

“…Severe hypercholesterolemia (LDL-cholesterol ≥ 5 mmol/l) is a major risk factor for coronary artery disease (CAD). The etiology incudes both genetic and…”
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Large registry-based analysis of genetic predisposition to tuberculosis identifies genetic risk factors at HLA by Tervi, Anniina, Junna, Nella, Broberg, Martin, Jones, Samuel E, Strausz, Satu, Kreivi, Hanna-Riikka, Heckman, Caroline A, Ollila, Hanna M

“…Tuberculosis is a significant public health concern resulting in the death of over 1 million individuals each year worldwide. While treatment options and…”
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Distinct and shared genetic architectures of gestational diabetes mellitus and type 2 diabetes by Elliott, Amanda, Walters, Raymond K., Pirinen, Matti, Kurki, Mitja, Junna, Nella, Goldstein, Jacqueline I., Reeve, Mary Pat, Siirtola, Harri, Lemmelä, Susanna M., Turley, Patrick, Lahtela, Elisa, Mehtonen, Juha, Reis, Kadri, Elnahas, Abdelrahman G., Reigo, Anu, Palta, Priit, Esko, Tõnu, Mägi, Reedik, Palotie, Aarno, Daly, Mark J., Widén, Elisabeth

“…Gestational diabetes mellitus (GDM) is a common metabolic disorder affecting more than 16 million pregnancies annually worldwide 1 , 2 . GDM is related to an…”
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How Communicating Polygenic and Clinical Risk for Atherosclerotic Cardiovascular Disease Impacts Health Behavior: an Observational Follow-up Study by Widén, Elisabeth, Junna, Nella, Ruotsalainen, Sanni, Surakka, Ida, Mars, Nina, Ripatti, Pietari, Partanen, Juulia J., Aro, Johanna, Mustonen, Pekka, Tuomi, Tiinamaija, Palotie, Aarno, Salomaa, Veikko, Kaprio, Jaakko, Partanen, Jukka, Hotakainen, Kristina, Pöllänen, Pasi, Ripatti, Samuli

“…Prediction tools that combine polygenic risk scores with clinical factors provide a new opportunity for improved prediction and prevention of atherosclerotic…”
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De Novo Mutations in the Motor Domain of KIF1A Cause Cognitive Impairment, Spastic Paraparesis, Axonal Neuropathy, and Cerebellar Atrophy by Lee, Jae-Ran, Srour, Myriam, Kim, Doyoun, Hamdan, Fadi. F., Lim, So-Hee, Brunel-Guitton, Catherine, Décarie, Jean-Claude, Rossignol, Elsa, Mitchell, Grant A., Schreiber, Allison, Moran, Rocio, Van Haren, Keith, Richardson, Randal, Nicolai, Joost, Oberndorff, Karin M.E.J., Wagner, Justin D., Boycott, Kym M., Rahikkala, Elisa, Junna, Nella, Tyynismaa, Henna, Cuppen, Inge, Verbeek, Nienke E., Stumpel, Connie T.R.M., Willemsen, Michel A., de Munnik, Sonja A., Rouleau, Guy A., Kim, Eunjoon, Kamsteeg, Erik-Jan, Kleefstra, Tjitske, Michaud, Jacques L.

“…ABSTRACT KIF1A is a neuron‐specific motor protein that plays important roles in cargo transport along neurites. Recessive mutations in KIF1A were previously…”
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LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels by Leinonen, Jaakko T., Chen, Yu-Chia, Pennonen, Jana, Lehtonen, Leevi, Junna, Nella, Tukiainen, Taru, Panula, Pertti, Widén, Elisabeth

“…Genome-wide association studies (GWAS) have recurrently associated sequence variation nearby LIN28B with pubertal timing, growth and disease. However, the…”
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Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes by Vogelezang, Suzanne, Bradfield, Jonathan P, Grant, Struan F A, Felix, Janine F, Jaddoe, Vincent W V

“…Head circumference is associated with intelligence and tracks from childhood into adulthood. We performed a genome-wide association study meta-analysis and…”
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How Communicating Polygenic and Clinical Risk for Atherosclerotic Cardiovascular Disease Impacts Health Behavior: an Observational Follow-up Study by Widén, Elisabeth, Junna, Nella, Ruotsalainen, Sanni, Surakka, Ida, Mars, Nina, Ripatti, Pietari, Partanen, Juulia J., Aro, Johanna, Mustonen, Pekka, Tuomi, Tiinamaija, Palotie, Aarno, Salomaa, Veikko, Kaprio, Jaakko, Partanen, Jukka, Hotakainen, Kristina, Pöllänen, Pasi, Ripatti, Samuli

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Truncated HSPB1 causes axonal neuropathy and impairs tolerance to unfolded protein stress by Ylikallio, Emil, Konovalova, Svetlana, Dhungana, Yogesh, Hilander, Taru, Junna, Nella, Partanen, Juhani V, Toppila, Jussi P, Auranen, Mari, Tyynismaa, Henna

“…HSPB1 belongs to the family of small heat shock proteins (sHSP) that have importance in protection against unfolded protein stress, in cancer cells for…”
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