Search Results - "Junkin, Michael"

Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids by Schuster, Brooke, Junkin, Michael, Kashaf, Sara Saheb, Romero-Calvo, Isabel, Kirby, Kori, Matthews, Jonathan, Weber, Christopher R., Rzhetsky, Andrey, White, Kevin P., Tay, Savaş

“…Three-dimensional (3D) cell culture technologies, such as organoids, are physiologically relevant models for basic and clinical applications. Automated…”
Get full text

High-Content Quantification of Single-Cell Immune Dynamics by Junkin, Michael, Kaestli, Alicia J., Cheng, Zhang, Jordi, Christian, Albayrak, Cem, Hoffmann, Alexander, Tay, Savaş

“…Cells receive time-varying signals from the environment and generate functional responses by secreting their own signaling molecules. Characterizing dynamic…”
Get full text

Spontaneous NF-κB activation by autocrine TNFα signaling: a computational analysis by Pękalski, Jakub, Zuk, Pawel J, Kochańczyk, Marek, Junkin, Michael, Kellogg, Ryan, Tay, Savaş, Lipniacki, Tomasz

“…NF-κB is a key transcription factor that regulates innate immune response. Its activity is tightly controlled by numerous feedback loops, including two…”
Get full text

Cellular self-organization by autocatalytic alignment feedback by Junkin, Michael, Leung, Siu Ling, Whitman, Samantha, Gregorio, Carol C, Wong, Pak Kin

“…Myoblasts aggregate, differentiate and fuse to form skeletal muscle during both embryogenesis and tissue regeneration. For proper muscle function, long-range…”
Get full text

Calcium wave propagation in networks of endothelial cells: model-based theoretical and experimental study by Long, Juexuan, Junkin, Michael, Wong, Pak Kin, Hoying, James, Deymier, Pierre

“…In this paper, we present a combined theoretical and experimental study of the propagation of calcium signals in multicellular structures composed of human…”
Get full text

Template‐Guided Self‐Assembly of Colloidal Quantum Dots Using Plasma Lithography by Junkin, Michael, Watson, Jennifer, Geest, Jonathan P. Vande, Wong, Pak Kin

“…A plasma lithography technique is developed to guide the self‐assembly of colloidal quantum dots and other nanoscale building blocks, including fluorescent…”
Get full text

Microfluidic single-cell analysis for systems immunology by Junkin, Michael, Tay, Savaş

“…The immune system constantly battles infection and tissue damage, but exaggerated immune responses lead to allergies, autoimmunity and cancer. Discrimination…”
Get more information

Probing cell migration in confined environments by plasma lithography by Junkin, Michael, Wong, Pak Kin

“…Abstract Cellular processes are regulated by various mechanical and physical factors in their local microenvironment such as geometric confinements,…”
Get full text

Spatiotemporal NF-κB dynamics encodes the position, amplitude, and duration of local immune inputs by Son, Minjun, Frank, Tino, Holst-Hansen, Thomas, Wang, Andrew G, Junkin, Michael, Kashaf, Sara S, Trusina, Ala, Tay, Savaş

“…Infected cells communicate through secreted signaling molecules like cytokines, which carry information about pathogens. How differences in cytokine secretion…”
Get full text

Mechanically induced intercellular calcium communication in confined endothelial structures by Junkin, Michael, Lu, Yi, Long, Juexuan, Deymier, Pierre A, Hoying, James B, Wong, Pak Kin

“…Abstract Calcium signaling in the diverse vascular structures is regulated by a wide range of mechanical and biochemical factors to maintain essential…”
Get full text

Spontaneous NF-[kappa]B Activation by Autocrine TNF[alpha] Signaling: A Computational Analysis by Pekalski, Jakub, Zuk, Pawel J, Kochanczyk, Marek, Junkin, Michael, Kellogg, Ryan, Tay, Savas, Lipniacki, Tomasz

“…NF-[kappa]B is a key transcription factor that regulates innate immune response. Its activity is tightly controlled by numerous feedback loops, including two…”
Get full text

Applications, techniques, and microfluidic interfacing for nanoscale biosensing by Kim, Jungkyu, Junkin, Michael, Kim, Deok-Ho, Kwon, Seunglee, Shin, Young Shik, Wong, Pak Kin, Gale, Bruce K.

“…Biosensors based on nanotechnology are rapidly developing and are becoming widespread in the biomedical field and analytical chemistry. For these…”
Get full text

Plasma lithography surface patterning for creation of cell networks by Junkin, Michael, Leung, Siu Ling, Yang, Yongliang, Lu, Yi, Volmering, Justin, Wong, Pak Kin

“…Systematic manipulation of a cell microenvironment with micro- and nanoscale resolution is often required for deciphering various cellular and molecular…”
Get full text

Evaporation-induced assembly of biomimetic polypeptides by Keyes, Joseph, Junkin, Michael, Cappello, Joseph, Wu, Xiaoyi, Wong, Pak Kin

“…We report an evaporation assisted plasma lithography (EAPL) process for guided self-assembly of a biomimetic silk-elastinlike protein (SELP). We demonstrate…”
Get full text

Microenvironments for study of myogenesis spatial organization and endothelial cell small messenger signaling by Junkin, Michael

“…In complex organisms, the combined actions of multiple cells enable higher order functions while using only the building blocks of individual cells…”
Get full text

Plasma Lithography Surface Patterning for Creation of Cell Networks by Junkin, Michael, Leung, Siu Ling, Yang, Yongliang, Lu, Yi, Volmering, Justin, Wong, Pak Kin

Get full text

Computational simulation of a magnetic microactuator for tissue engineering applications by Keyes, Joseph, Junkin, Michael, Wong, Pak Kin, Vande Geest, Jonathan P

“…The next generation of tissue engineered constructs (TECs) requires the incorporation of a controllable and optimized microstructure if they are to chemically,…”
Get full text

Microenvironments for study of myogenesis spatial organization and endothelial cell small messenger signaling by Junkin, Michael

“…In complex organisms, the combined actions of multiple cells enable higher order functions while using only the building blocks of individual cells…”
Get full text

Plasma lithography for probing collective cell behaviors by Junkin, M., Pak Kin Wong

“…Collective cell motions play essential roles in the regulation of various complex biological processes such as embryogenesis, tissue regeneration, and…”
Get full text

A mechanostimulation system for revealing intercellular calcium communication in HUVEC networks by Junkin, M., Yi Lu, Juexuan Long, Deymier, P. A., Hoying, J. B., Pak Kin Wong

“…This paper reports a mechanostimulation system for studying mechanically induced intercellular calcium signaling in networks of human umbilical vein…”
Get full text