Search Results - "Junker, Caroline"

Faecal virome transplantation decreases symptoms of type 2 diabetes and obesity in a murine model by Rasmussen, Torben Sølbeck, Mentzel, Caroline Märta Junker, Kot, Witold, Castro-Mejía, Josué Leonardo, Zuffa, Simone, Swann, Jonathan Richard, Hansen, Lars Hestbjerg, Vogensen, Finn Kvist, Hansen, Axel Kornerup, Nielsen, Dennis Sandris

“…Development of obesity and type 2 diabetes (T2D) are associated with gut microbiota (GM) changes. The gut viral community is predominated by bacteriophages…”
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Gender and Obesity Specific MicroRNA Expression in Adipose Tissue from Lean and Obese Pigs by Mentzel, Caroline M Junker, Anthon, Christian, Jacobsen, Mette J, Karlskov-Mortensen, Peter, Bruun, Camilla S, Jørgensen, Claus B, Gorodkin, Jan, Cirera, Susanna, Fredholm, Merete

“…Obesity is a complex condition that increases the risk of life threatening diseases such as cardiovascular disease and diabetes. Studying the gene regulation…”
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Low‐gainer diet‐induced obese microbiota transplanted mice exhibit increased fighting by Junker Mentzel, Caroline M., Hui, Yan, Hammerich, Tanja Maria Stentoft, Klug‐Dambmann, Malene, Liu, Yi, Zachariassen, Line Fisker, Hansen, Lars Hestbjerg, Aslampaloglou, Antonios, Kiersgaard, Maria, Nielsen, Dennis Sandris, Hansen, Axel Kornerup, Krych, Lukasz

“…Weight gain variation is a great challenge in diet‐induced obesity studies since low‐gainer animals are of limited experimental value. The inbred C57BL/6 (B6)…”
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Joint Profiling of miRNAs and mRNAs Reveals miRNA Mediated Gene Regulation in the Göttingen Minipig Obesity Model by Mentzel, Caroline M Junker, Alkan, Ferhat, Keinicke, Helle, Jacobsen, Mette J, Gorodkin, Jan, Fredholm, Merete, Cirera, Susanna

“…Obesity and its comorbidities are an increasing challenge for both affected individuals and health care systems, worldwide. In obese individuals, perturbation…”
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FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation by Keinicke, Helle, Sun, Gao, Mentzel, Caroline M Junker, Fredholm, Merete, John, Linu Mary, Andersen, Birgitte, Raun, Kirsten, Kjaergaard, Marina

“…The prevalence of non-alcoholic fatty liver disease (NAFLD) has increased dramatically worldwide and, subsequently, also the risk of developing non-alcoholic…”
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Oligosaccharide equine feed supplement, Immulix, has minor impact on vaccine responses in mice by Henriksen, Ida Wang, Mejia, Josue Leonardo Castro, Mentzel, Caroline Martha Junker, Lindenberg, Frederikke, Hansen, Axel Kornerup

“…Several mammalian species are vaccinated in early life, but little is known about the effect of diet on vaccine response. Oligosaccharides are increasingly…”
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Controlling the uncontrolled variation in the diet induced obese mouse by microbiomic characterization by Bondarenko, Valeriia, Løkke, Cecillie Reynolds, Dobrowolski, Peter, Mentzel, Caroline Junker, Castro-Mejía, Josué L., Hansen, Camilla Hartmann Friis, Sørensen, Dorte Bratbo, Nielsen, Dennis Sandris, Krych, Lukasz, Hansen, Axel Kornerup

“…Group sizes in an animal study are calculated from estimates on variation, effect, power and significance level. Much of the variation in glucose related…”
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Fecal virome transfer improves proliferation of commensal gut Akkermansia muciniphila and unexpectedly enhances the fertility rate in laboratory mice by Rasmussen, Torben Sølbeck, Mentzel, Caroline M. Junker, Danielsen, Malene Refslund, Jakobsen, Rasmus Riemer, Zachariassen, Line Sidsel Fisker, Castro Mejia, Josue Leonardo, Brunse, Anders, Hansen, Lars Hestbjerg, Hansen, Camilla Hartmann Friis, Hansen, Axel Kornerup, Nielsen, Dennis Sandris

“…Probiotics are intended to improve gastrointestinal health when consumed. However, the probiotics marketed today only colonize the densely populated gut to a…”
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Cesarean section induced dysbiosis promotes type 2 immunity but not oxazolone-induced dermatitis in mice by Zachariassen, Line Fisker, Ebert, Maria Bernadette Bergh, Mentzel, Caroline Märta Junker, Deng, Ling, Krych, Lukasz, Nielsen, Dennis Sandris, Stokholm, Jakob, Hansen, Camilla Hartmann Friis

“…Delivery by cesarean section (CS) is associated with an altered gut microbiota (GM) colonization and a higher risk of later chronic inflammatory diseases…”
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Short communication: Gut microbial colonization of the mouse colon using faecal transfer was equally effective when comparing rectal inoculation and oral inoculation based on 16S rRNA sequencing by Lützhøft, Ditte Olsen, Sánchez-Alcoholado, Lidia, Tougaard, Peter, Junker Mentzel, Caroline M., Kot, Witold, Nielsen, Dennis S., Hansen, Axel Kornerup

“…In the present study we hypothesized that a higher degree of gut microbiota (GM) transfer and colonization could be reached by rectal inoculation compared to…”
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Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity by Simar, David, Barrès, Romain, Jørgensen, Claus B., Huby, Thierry, Olesen, Ann Sofie, Mentzel, Caroline M. Junker, Jacobsen, Mette J., Fredholm, Merete

“…Obesity is associated with immunological perturbations that contribute to insulin resistance. Epigenetic mechanisms can control immune functions and have been…”
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Epigenetic and Transcriptomic Characterization of Pure Adipocyte Fractions From Obese Pigs Identifies Candidate Pathways Controlling Metabolism by Jacobsen, Mette Juul, Havgaard, Jakob H, Anthon, Christian, Mentzel, Caroline M Junker, Cirera, Susanna, Krogh, Poula Maltha, Pundhir, Sachin, Karlskov-Mortensen, Peter, Bruun, Camilla S, Lesnik, Philippe, Guerin, Maryse, Gorodkin, Jan, Jørgensen, Claus B, Fredholm, Merete, Barrès, Romain

“…Reprogramming of adipocyte function in obesity is implicated in metabolic disorders like type 2 diabetes. Here, we used the pig, an animal model sharing many…”
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Deregulation of obesity-relevant genes is associated with progression in BMI and the amount of adipose tissue in pigs by Mentzel, Caroline M. Junker, Cardoso, Tainã Figueiredo, Pipper, Christian Bressen, Jacobsen, Mette Juul, Jørgensen, Claus Bøttcher, Cirera, Susanna, Fredholm, Merete

“…The aim of this study was to elucidate the relative impact of three phenotypes often used to characterize obesity on perturbation of molecular pathways…”
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Fat and carbohydrate content in the diet induces drastic changes in gene expression in young Göttingen minipigs by Mentzel, Caroline M. Junker, Cardoso, Tainã Figueiredo, Lex, Annika M. J., Sørensen, Dorte Bratbo, Fredholm, Merete, Cirera, Susanna

“…In human health, there is interest in developing specific diets to reduce body weight. These studies are mainly focused on phenotypic changes induced in blood…”
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Phosphorus Binding Sites in Proteins: Structural Preorganization and Coordination by Gruber, Mathias, Greisen, Per, Junker, Caroline M, Hélix-Nielsen, Claus

“…Phosphorus is a ubiquitous element of the cell, which is found throughout numerous key molecules related to cell structure, energy and information storage and…”
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The Role of First and Second Shell Interactions in Phosphate Binding Proteins by Gruber, Mathias, Junker, Caroline, Greisen, Per, Hélix-Nielsen, Claus

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ServiceNavigator - A Bayesian Assistance System for Diagnosing Industrial Production Systems by Diedrich, Alexander, Deutschmann, Patrick, Junker, Caroline

“…Service technicians servicing machines in small-and medium-sized enterprises face the challenge to diagnose machines with increasing complexity in less time…”
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