Search Results - "Junker, Alex"
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1
Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice
Published in Nature communications (10-08-2023)“…The brain and behavior are under energetic constraints, limited by mitochondrial energy transformation capacity. However, the mitochondria-behavior…”
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2
Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures
Published in eLife (26-10-2021)“…Using a high-throughput mitochondrial phenotyping platform to quantify multiple mitochondrial features among molecularly defined immune cell subtypes, we…”
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3
Taurine deficiency as a driver of aging
Published in Science (American Association for the Advancement of Science) (09-06-2023)“…Aging is associated with changes in circulating levels of various molecules, some of which remain undefined. We find that concentrations of circulating taurine…”
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4
A cardiac amino-terminal GRK2 peptide inhibits insulin resistance yet enhances maladaptive cardiovascular and brown adipose tissue remodeling in females during diet-induced obesity
Published in Journal of molecular and cellular cardiology (01-10-2023)“…Obesity and metabolic disorders are increasing in epidemic proportions, leading to poor outcomes including heart failure. With a growing recognition of the…”
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Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta‐analysis
Published in The FASEB journal (01-02-2022)“…Mitochondria are maternally inherited organelles that play critical tissue‐specific roles, including hormone synthesis and energy production, that influence…”
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Integrating sex and gender in mitochondrial science
Published in Current opinion in physiology (01-04-2022)“…Mitochondria play vital roles in the production of energy and sex hormones. To date, little is known about how sex and gender influence mitochondrial biology…”
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7
Ketogenesis promotes tolerance to Pseudomonas aeruginosa pulmonary infection
Published in Cell metabolism (03-10-2023)“…Pseudomonas aeruginosa is a common cause of pulmonary infection. As a Gram-negative pathogen, it can initiate a brisk and highly destructive inflammatory…”
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A platform to map the mind–mitochondria connection and the hallmarks of psychobiology: the MiSBIE study
Published in Trends in endocrinology and metabolism (01-10-2024)“…Mitochondria transform the oxygen we breathe and the food we eat to power all brain–body or mind–body processes that produce human experiences.Experimental…”
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A Cardiac Amino-Terminal GRK2 Peptide Inhibits Maladaptive Adipocyte Hypertrophy and Insulin Resistance During Diet-Induced Obesity
Published in JACC. Basic to translational science (01-06-2022)“…[Display omitted] •Heart disease remains the leading cause of death, in part due to increasing diabetes and obesity, though the exact mechanisms linking these…”
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