Search Results - "Junior, Claudio Antônio da Silva"
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Application of the UV–vis spectrophotometry method for the determination of glutamate in the cerebrospinal fluid of rats
Published in Journal of pharmaceutical and biomedical analysis (15-07-2020)“…•Spectrophotometry of CSF glutamate levels is reliable.•More sustainable method for CSF glutamate dosing.•Useful for academic research detection. In…”
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Current Drug Development Overview: Targeting Voltage-Gated Calcium Channels for the Treatment of Pain
Published in International journal of molecular sciences (25-05-2023)“…Voltage-gated calcium channels (VGCCs) are targeted to treat pain conditions. Since the discovery of their relation to pain processing control, they are…”
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Calcium channels blockers toxins attenuate abdominal hyperalgesia and inflammatory response associated with the cerulein-induced acute pancreatitis in rats
Published in European journal of pharmacology (15-01-2021)“…Agents that modulate the activity of high-voltage gated calcium channels (HVCCs) exhibit experimentally and clinically significant effect by relieving visceral…”
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PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina
Published in Toxins (11-03-2016)“…The in vivo neuroprotective effect of PhTx3-4, a spider toxin N-P/Q calcium channel blocker, was studied in a rat model of NMDA-induced injury of the retina…”
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Analgesic effects of the CTK 01512-2 toxin in different models of orofacial pain in rats
Published in Pharmacological reports (01-06-2020)“…Orofacial pain is clinically challenging, having therapeutic failures and side effects. This study evaluated the antinociceptive activities of the CTK 01512-2…”
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The inhibitory effect of Phα1β toxin on diabetic neuropathic pain involves the CXCR4 chemokine receptor
Published in Pharmacological reports (01-02-2020)“…Diabetic neuropathy is a common cause of painful diabetic neuropathy (PDN). C-X-C chemokine receptor type 4 (CXCR4) expression is increased in peripheral nerve…”
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