Search Results - "Junior, Adalberto Pessoa"
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1
A biotechnology perspective of fungal proteases
Published in Brazilian journal of microbiology (01-06-2015)“…Proteases hydrolyze the peptide bonds of proteins into peptides and amino acids, being found in all living organisms, and are essential for cell growth and…”
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2
Development of L-Asparaginase Biobetters: Current Research Status and Review of the Desirable Quality Profiles
Published in Frontiers in bioengineering and biotechnology (10-01-2019)“…L-Asparaginase (ASNase) is a vital component of the first line treatment of acute lymphoblastic leukemia (ALL), an aggressive type of blood cancer expected to…”
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3
Different types of aqueous two-phase systems for biomolecule and bioparticle extraction and purification
Published in Biotechnology progress (01-11-2013)“…Upstream improvements have led to significant advances in the productivity of biomolecules and bioparticles. Today, downstream processes are the bottleneck in…”
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4
Production of a novel N‐terminal PEGylated crisantaspase
Published in Biotechnology and applied biochemistry (01-05-2019)“…Crisantaspase is an asparaginase enzyme produced by Erwinia chrysanthemi and used to treat acute lymphoblastic leukemia (ALL) in case of hypersensitivity to…”
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5
Phase Diagrams of the Aqueous Two-Phase Systems of Poly(ethylene glycol)/Sodium Polyacrylate/Salts
Published in Polymers (01-03-2011)“…Aqueous two-phase systems consisting of polyethylene glycol (PEG), sodium polyacrylate (NaPAA), and a salt have been studied. The effects of the polymer size,…”
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6
Cultivation of Pichia pastoris carrying the scFv anti LDL (−) antibody fragment. Effect of preculture carbon source
Published in Brazilian journal of microbiology (01-07-2017)“…Antibodies and antibody fragments are nowadays among the most important biotechnological products, and Pichia pastoris is one of the most important vectors to…”
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7
Experimental and Theoretical Investigation of the Micellar-Assisted Solubilization of Ibuprofen in Aqueous Media
Published in Langmuir (14-02-2006)“…Surfactants can be used to increase the solubility of poorly soluble drugs in water and to increase drug bioavailability. In this article, the aqueous…”
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Aqueous two-phase extraction using thermoseparating copolymer: a new system for phenolic compounds removal from hemicelullosic hydrolysate
Published in Journal of chemical technology and biotechnology (1986) (01-02-2008)“…BACKGROUND: The hydrolysis of hemicellulosic material can provide liquor with high xylose concentration (which can be used as a fermentation medium) and…”
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9
Production, purification and characterization of an aspartic protease from Aspergillus foetidus
Published in Food and chemical toxicology (01-11-2017)“…An acidic thermostable protease was extracellularly produced either in shake flask or in stirred tank bioreactor by an Aspergillus foetidus strain isolated…”
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10
Kinetic and thermodynamic studies of a novel acid protease from Aspergillus foetidus
Published in International journal of biological macromolecules (01-11-2015)“…The kinetics of a thermostable extracellular acid protease produced by an Aspergillus foetidus strain was investigated at different pH, temperatures and…”
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11
An improved method for simple and accurate colorimetric determination of l‐asparaginase enzyme activity using Nessler's reagent
Published in Journal of chemical technology and biotechnology (1986) (01-05-2021)“…BACKGROUND Colorimetric determination of l‐asparaginase enzyme activity most commonly uses Nessler's reagent, but often yields unreliable results due to…”
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12
Liquid–liquid extraction of biopharmaceuticals from fermented broth: trends and future prospects
Published in Journal of chemical technology and biotechnology (1986) (01-07-2018)“…Biopharmaceuticals are one of the most important groups of biotechnological products, representing one‐quarter of all pharmaceutical sales and providing…”
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13
Biochemical characteristics and potential application of a novel ethanol and glucose-tolerant β-glucosidase secreted by Pichia guilliermondii G1.2
Published in Journal of biotechnology (20-03-2019)“…•A novel ethanol and glucose-tolerant β-glucosidase.•Potential application for cellulosic ethanol production and in winemaking.•β-glucosidase was no able to…”
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14
Novel site-specific PEGylated L-asparaginase
Published in PloS one (12-02-2019)“…L-asparaginase (ASNase) from Escherichia coli is currently used in some countries in its PEGylated form (ONCASPAR, pegaspargase) to treat acute lymphoblastic…”
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15
Biological and physicochemical stability of ceftazidime and aminophylline on glucose parenteral solution
Published in Brazilian Journal of Pharmaceutical Sciences (01-12-2012)“…Ceftazidime is a broad spectrum antibiotic administered mainly by the parenteral route, and it is especially effective against Pseudomonas aeruginosa. The…”
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16
PEG/NaPA aqueous two-phase systems for the purification of proteases expressed by Penicillium restrictum from Brazilian Savanna
Published in Process biochemistry (1991) (01-12-2014)“…•We optimized the extraction of proteases produced by Penicillium restrictum.•The enzymes were produced in medium containing agroindustrial residue.•An…”
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17
Laccases produced by Peniophora from marine and terrestrial origin: A comparative study
Published in Biocatalysis and agricultural biotechnology (01-08-2021)“…Although fungal laccases have been widely applied in environmental and industrial processes, little is known about laccases produced by marine fungi. In this…”
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L-Asparaginase from Penicillium sizovae Produced by a Recombinant Komagataella phaffii Strain
Published in Pharmaceuticals (Basel, Switzerland) (14-06-2022)“…L-asparaginase is an important enzyme in the pharmaceutical field used as treatment for acute lymphoblastic leukemia due to its ability to hydrolyze…”
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Correction: Novel site-specific PEGylated L-asparaginase
Published in PloS one (24-10-2019)“…[This corrects the article DOI: 10.1371/journal.pone.0211951.]…”
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Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds
Published in Materials research (São Carlos, São Paulo, Brazil) (01-03-2017)“…The main aim of this study was to develop scaffolds based on alginate, chitosan and hybrid fibers with and without glycerol. The scaffolds developed underwent…”
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