Search Results - "Junho Chung"

Adenylyl Cyclase-Associated Protein 1 Is a Receptor for Human Resistin and Mediates Inflammatory Actions of Human Monocytes by Lee, Sahmin, Lee, Hyun-Chae, Kwon, Yoo-Wook, Lee, Sang Eun, Cho, Youngjin, Kim, Joonoh, Lee, Soobeom, Kim, Ju-Young, Lee, Jaewon, Yang, Han-Mo, Mook-Jung, Inhee, Nam, Ky-Youb, Chung, Junho, Lazar, Mitchell A., Kim, Hyo-Soo

“…Human resistin is a cytokine that induces low-grade inflammation by stimulating monocytes. Resistin-mediated chronic inflammation can lead to obesity,…”
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An anti-Gn glycoprotein antibody from a convalescent patient potently inhibits the infection of severe fever with thrombocytopenia syndrome virus by Kim, Ki Hyun, Kim, Jinhee, Ko, Meehyun, Chun, June Young, Kim, Hyori, Kim, Seungtaek, Min, Ji-Young, Park, Wan Beom, Oh, Myoung-Don, Chung, Junho

“…Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease localized to China, Japan, and Korea that is characterized by severe…”
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Next-generation sequencing enables the discovery of more diverse positive clones from a phage-displayed antibody library by Yang, Wonjun, Yoon, Aerin, Lee, Sanghoon, Kim, Soohyun, Han, Jungwon, Chung, Junho

“…Phage display technology provides a powerful tool to screen a library for a binding molecule via an enrichment process. It has been adopted as a critical…”
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An ancestral SARS-CoV-2 vaccine induces anti-Omicron variants antibodies by hypermutation by Park, Seoryeong, Choi, Jaewon, Lee, Yonghee, Noh, Jinsung, Kim, Namphil, Lee, JinAh, Cho, Geummi, Kim, Sujeong, Yoo, Duck Kyun, Kang, Chang Kyung, Choe, Pyoeng Gyun, Kim, Nam Joong, Park, Wan Beom, Kim, Seungtaek, Oh, Myoung-don, Kwon, Sunghoon, Chung, Junho

“…The immune escape of Omicron variants significantly subsides by the third dose of an mRNA vaccine. However, it is unclear how Omicron variant-neutralizing…”
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Laser-Assisted Recovery of On-Chip Phage Viral DNA for Phage Fluorescence Immunoassay Microchip by Chang, Seohee, Kim, Soohyun, Lee, Daewon, Lee, Seung Ah, Chung, Junho, Kwon, Sunghoon, Kim, Junhoi

“…Laser-assisted recovery of on-chip phage viral DNA was demonstrated. Optomechanical energy conversion was utilized to shear off a part of a microchip and…”
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Spatial epitranscriptomics reveals A-to-I editome specific to cancer stem cell microniches by Lee, Amos C., Lee, Yongju, Choi, Ahyoun, Lee, Han-Byoel, Shin, Kyoungseob, Lee, Hyunho, Kim, Ji Young, Ryu, Han Suk, Kim, Hoe Suk, Ryu, Seung Yeon, Lee, Sangeun, Cheun, Jong-Ho, Yoo, Duck Kyun, Lee, Sumin, Choi, Hansol, Ryu, Taehoon, Yeom, Huiran, Kim, Namphil, Noh, Jinsung, Lee, Yonghee, Kim, Inyoung, Bae, Sangwook, Kim, Jinhyun, Lee, Wooseok, Kim, Okju, Jung, Yushin, Kim, Changhoe, Song, Seo Woo, Choi, Yeongjae, Chung, Junho, Kim, Byung Gee, Han, Wonshik, Kwon, Sunghoon

“…Epitranscriptomic features, such as single-base RNA editing, are sources of transcript diversity in cancer, but little is understood in terms of their spatial…”
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Identification of B cell subsets based on antigen receptor sequences using deep learning by Lee, Hyunho, Shin, Kyoungseob, Lee, Yongju, Lee, Soobin, Lee, Seungyoun, Lee, Eunjae, Kim, Seung Woo, Shin, Ha Young, Kim, Jong Hoon, Chung, Junho, Kwon, Sunghoon

“…B cell receptors (BCRs) denote antigen specificity, while corresponding cell subsets indicate B cell functionality. Since each B cell uniquely encodes this…”
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Vaccination with single plasmid DNA encoding IL-12 and antigens of severe fever with thrombocytopenia syndrome virus elicits complete protection in IFNAR knockout mice by Kang, Jun-Gu, Jeon, Kyeongseok, Choi, Hooncheol, Kim, Yuri, Kim, Hong-Il, Ro, Hyo-Jin, Seo, Yong Bok, Shin, Jua, Chung, Junho, Jeon, Yoon Kyung, Kim, Yang Soo, Lee, Keun Hwa, Cho, Nam-Hyuk

“…Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by SFTS virus (SFTSV) infection. Despite a gradual increase of SFTS…”
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Alleviation of Hydrogen Embrittlement to Delay Effective Hydrogen Diffusion Against MA Constituent Formation Due to Mo Solutes for 420 MPa Grade Offshore Steels by Nam, Jimin, Lee, Junghoon, Park, Hanji, Park, Cheolho, Lee, Changhoon, Chung, Junho, Lee, Seung-gun, Kang, Namhyun

“…Hydrogen embrittlement (HE) is a significant issue in high-strength offshore steel. Mo is added for high strength, and several studies on the HE resistance by…”
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Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells by Yin, Jinlong, Park, Gunwoo, Kim, Tae Hoon, Hong, Jun Hee, Kim, Youn-Jae, Jin, Xiong, Kang, Sangjo, Jung, Ji-Eun, Kim, Jeong-Yub, Yun, Hyeongsun, Lee, Jeong Eun, Kim, Minkyung, Chung, Junho, Kim, Hyunggee, Nakano, Ichiro, Gwak, Ho-Shin, Yoo, Heon, Yoo, Byong Chul, Kim, Jong Heon, Hur, Eun-Mi, Lee, Jeongwu, Lee, Seung-Hoon, Park, Myung-Jin, Park, Jong Bae

“…Epidermal growth factor receptor variant III (EGFRvIII) has been associated with glioma stemness, but the direct molecular mechanism linking the two is largely…”
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Heterologous vaccination utilizing viral vector and protein platforms confers complete protection against SFTSV by Kim, Jae-Yong, Jeon, Kyeongseok, Hong, Jung Joo, Park, Sang-In, Cho, Hyeonggon, Park, Hyo-Jung, Kwak, Hye Won, Park, Hyeong-Jun, Bang, Yoo-Jin, Lee, Yu-Sun, Bae, Seo-Hyeon, Kim, So-Hee, Hwang, Kyung-Ah, Jung, Dae-Im, Cho, Seong Hoo, Seo, Sang Hwan, Kim, Green, Oh, Hanseul, Lee, Hwal-Yong, Kim, Ki Hyun, Lim, Hee-Young, Jeon, Pyeonghwa, Lee, Joo-Yeon, Chung, Junho, Lee, Sang-Myeong, Ko, Hae Li, Song, Manki, Cho, Nam-Hyuk, Lee, Young-suk, Hong, So-Hee, Nam, Jae-Hwan

“…Severe fever with thrombocytopenia syndrome virus was first discovered in 2009 as the causative agent of severe fever with thrombocytopenia syndrome. Despite…”
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Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma: a first-in-human study by Zhang, Yunlin, Patel, Ruchi P, Kim, Ki Hyun, Cho, Hyungwoo, Jo, Jae-Cheol, Jeong, Seong Hyun, Oh, Sung Yong, Choi, Yoon Seok, Kim, Sung Hyun, Lee, Ji Hyun, Angelos, Mathew, Guruprasad, Puneeth, Cohen, Ivan, Ugwuanyi, Ositadimma, Lee, Yong Gu, Pajarillo, Raymone, Cho, Jong Hyun, Carturan, Alberto, Paruzzo, Luca, Ghilardi, Guido, Wang, Michael, Kim, Soohwan, Kim, Sung-Min, Lee, Hyun-Jong, Park, Ji-Ho, Cui, Leiguang, Lee, Tae Bum, Hwang, In-Sik, Lee, Young-Ha, Lee, Yong-Jun, Porazzi, Patrizia, Liu, Dongfang, Lee, Yoon, Kim, Jong-Hoon, Lee, Jong-Seo, Yoon, Dok Hyun, Chung, Junho, Ruella, Marco

“…Commercial anti-CD19 chimeric antigen receptor T-cell therapies (CART19) are efficacious against advanced B-cell non-Hodgkin lymphoma (NHL); however, most…”
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Virus Templated Gold Nanocube Chain for SERS Nanoprobe by Lee, Hye-Eun, Lee, Hwa Kyoung, Chang, Hyejin, Ahn, Hyo-Yong, Erdene, Norov, Lee, Ho-Young, Lee, Yoon-Sik, Jeong, Dae Hong, Chung, Junho, Nam, Ki Tae

“…A M13 virus based SERS nanoprobe is presented. Gold nanocubes closely aligned into chains along the length of the virus intensify Raman signals of various…”
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Chicken scFvs with an Artificial Cysteine for Site-Directed Conjugation by Yoon, Aerin, Shin, Jung Won, Kim, Soohyun, Kim, Hyori, Chung, Junho

“…For the site-directed conjugation of chemicals and radioisotopes to the chicken-derived single-chain variable fragment (scFv), we investigated amino acid…”
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Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion by Kim, Minsoo, Yoon, Soomin, Lee, Sukmook, Ha, Seon Ah, Kim, Hyun Kee, Kim, Jin Woo, Chung, Junho

“…Gremlin-1, a bone morphogenetic protein (BMP) antagonist, is overexpressed in various cancerous tissues but its role in carcinogenesis has not been…”
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An anti-EGFR × cotinine bispecific antibody complexed with cotinine-conjugated duocarmycin inhibits growth of EGFR-positive cancer cells with KRAS mutations by Jin, Junyeong, Park, Gunwoo, Park, Jong Bae, Kim, Soohyun, Kim, Hyori, Chung, Junho

“…Antibody-drug conjugates (ADCs) can selectively deliver cytotoxic agents to tumor cells and are frequently more potent than naked antibodies. However,…”
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Optimization of peripheral blood volume for in silico reconstitution of the human B‐cell receptor repertoire by Lee, Hyunho, Yoo, Duck Kyun, Han, Jerome, Kim, Ki Hyun, Noh, Jinsung, Lee, Yonghee, Lee, Eunjae, Kwon, Sunghoon, Chung, Junho

“…B cells recognize antigens via membrane‐expressed B‐cell receptors (BCR) and antibodies. Similar human BCR sequences are frequently found at a significantly…”
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Efficient Selection of Antibodies Reactive to Homologous Epitopes on Human and Mouse Hepatocyte Growth Factors by Next-Generation Sequencing-Based Analysis of the B Cell Repertoire by Kim, Soohyun, Lee, Hyunho, Noh, Jinsung, Lee, Yonghee, Han, Haejun, Yoo, Duck Kyun, Kim, Hyori, Kwon, Sunghoon, Chung, Junho

“…YYB-101 is a humanized rabbit anti-human hepatocyte growth factor (HGF)-neutralizing antibody currently in clinical trial. To test the effect of HGF…”
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A modifiable universal cotinine-chimeric antigen system of NK cells with multiple targets by Kang, Hee Young, Lee, Soo Yun, Kim, Hyun Min, Lee, Su Ui, Lee, Hyunseung, Cho, Mi Young, Oh, Se-Chan, Kim, Seok-Min, Park, Hye Sun, Han, Eun Hee, Kim, Seong-Eun, Kim, Hyori, Yoon, Suk Ran, Doh, Junsang, Chung, Junho, Hong, Kwan Soo, Choi, Inpyo, Kim, Tae-Don

“…Natural killer (NK) cells are immune effector cells with outstanding features for adoptive immunotherapy. Immune effector cells with chimeric antigen receptors…”
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Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabody by Koo, Mi Young, Park, Jiyoung, Lim, Jung Mi, Joo, Sei Yoon, Shin, Seung-Pil, Bo Shim, Hyun, Chung, Junho, Kang, Dongmin, Woo, Hyun Ae, Rhee, Sue Goo

“…Signal transducer and activator of transcription 3 (STAT3) is a multifunctional protein that participates in signaling pathways initiated by various growth…”
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