Search Results - "Junginger, Lucas"

Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 in osteoarthritis by Knights, Alexander J, Farrell, Easton C, Ellis, Olivia M, Lammlin, Lindsey, Junginger, Lucas M, Rzeczycki, Phillip M, Bergman, Rachel F, Pervez, Rida, Cruz, Monique, Knight, Eleanor, Farmer, Dennis, Samani, Alexa A, Wu, Chia-Lung, Hankenson, Kurt D, Maerz, Tristan

“…Synovium is acutely affected following joint trauma and contributes to post-traumatic osteoarthritis (PTOA) progression. Little is known about discrete cell…”
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Intra-articular sprouting of nociceptors accompanies progressive osteoarthritis: comparative evidence in four murine models by Obeidat, Alia M, Ishihara, Shingo, Li, Jun, Adamczyk, Natalie S, Lammlin, Lindsey, Junginger, Lucas, Maerz, Tristan, Miller, Richard J, Miller, Rachel E, Malfait, Anne-Marie

“…Knee joints are densely innervated by nociceptors. In human knees and rodent models, sprouting of nociceptors has been reported in late-stage osteoarthritis…”
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Local and Systemic Effects of Blood Flow Restriction Therapy in an Animal Model by Ramme, Austin J., Darcy, Rose, Rourke, Brennan J., Davis, Carol, Markworth, James F., Junginger, Lucas, Maerz, Tristan, Brooks, Susan V., Bedi, Asheesh

“…Background: Blood flow restriction therapy (BFRT) has been increasingly applied to improve athletic performance and injury recovery. Validation of BFRT has…”
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Patient-Perceived Outcomes Improve Faster Than Hip Strength in Recovery After Surgical Correction for Symptomatic Femoroacetabular Impingement by Konnaris, Maxwell A., Junginger, Lucas M., Sibilsky Enselman, Elizabeth R., Bell, Richard D., Maerz, Tristan, Bedi, Asheesh

“…Background: Patients with symptomatic femoroacetabular impingement (FAI) have hip strength deficits, instability, and increased risk for concomitant injury…”
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An Assessment of Hip Strength, Patient Reported Outcomes, and Plasma Inflammatory Biomarkers After Surgical Correction for Symptomatic Femoroacetabular Impingement by Mendias, Christopher, Bedi, Asheesh, Maerz, Tristan, Junginger, Lucas, Enselman, Elizabeth, Konnaris, Maxwell

“…Objectives: Patients with Femoroacetabular impingement (FAI) have been shown to have elevated circulating biomarkers of inflammation and cartilage catabolism,…”
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Automated MicroCT-based bone and articular cartilage analysis using iterative shape averaging and atlas-based registration by Newton, Michael D., Junginger, Lucas, Maerz, Tristan

“…Micro-computed tomography (μCT) and contrast-enhanced μCT are important tools for preclinical analysis of bone and articular cartilage (AC). Quantitative data…”
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Sexual dimorphism of the synovial transcriptome underpins greater PTOA disease severity in male mice following joint injury by Bergman, Rachel F., Lammlin, Lindsey, Junginger, Lucas, Farrell, Easton, Goldman, Sam, Darcy, Rose, Rasner, Cody, Obeidat, Alia M., Malfait, Anne-Marie, Miller, Rachel E., Maerz, Tristan

“…Osteoarthritis (OA) is a disease with sex-dependent prevalence and severity in both human and animal models. We sought to elucidate sex differences in…”
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Traumatic joint injury induces acute catabolic bone turnover concurrent with articular cartilage damage in a rat model of posttraumatic osteoarthritis by Maerz, Tristan, Newton, Michael D., Fleischer, Mackenzie, Hartner, Samantha E., Gawronski, Karissa, Junginger, Lucas, Baker, Kevin C.

“…Assess acute alterations in bone turnover, microstructure, and histomorphometry following noninvasive anterior cruciate ligament rupture (ACLR). Twelve female…”
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Cannabinoid receptor type 2 is upregulated in synovium following joint injury and mediates anti-inflammatory effects in synovial fibroblasts and macrophages by Rzeczycki, P., Rasner, C., Lammlin, L., Junginger, L., Goldman, S., Bergman, R., Redding, S., Knights, A.J., Elliott, M., Maerz, T.

“…Joint injury-induced perturbations to the endocannabinoid system (ECS), a regulator of both inflammation and nociception, remain largely uncharacterized. We…”
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Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1 by Tsou, Pei-Suen, Lu, Chenyang, Gurrea-Rubio, Mikel, Muraoka, Sei, Campbell, Phillip L, Wu, Qi, Model, Ellen N, Lind, Matthew E, Vichaikul, Sirapa, Mattichak, Megan N, Brodie, William D, Hervoso, Jonatan L, Ory, Sarah, Amarista, Camila I, Pervez, Rida, Junginger, Lucas, Ali, Mustafa, Hodish, Gal, O'Mara, Morgan M, Ruth, Jeffrey H, Robida, Aaron M, Alt, Andrew J, Zhang, Chengxin, Urquhart, Andrew G, Lawton, Jeffrey N, Chung, Kevin C, Maerz, Tristan, Saunders, Thomas L, Groppi, Vincent E, Fox, David A, Amin, M Asif

“…CD13, an ectoenzyme on myeloid and stromal cells, also circulates as a shed, soluble protein (sCD13) with powerful chemoattractant, angiogenic, and…”
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