Search Results - "Jungbluth, G L"

Age and sex effects on the pharmacokinetics of linezolid by SISSON, T. Lasher, JUNGBLUTH, G. L, HOPKINS, N. K

“…To evaluate the possible effects of age and sex on the pharmacokinetics of linezolid in healthy volunteers. A single 600-mg dose of linezolid was administered…”
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A Pharmacokinetic Evaluation of Concomitant Administration of Linezolid and Aztreonam by Sisson, Theresa Lasher, Jungbluth, Gail L., Hopkins, Nancy K.

“…Linezolid, a new oxazolidinone antimicrobial agent, has a spectrum of activity encompassing a wide variety of Gram‐positive bacteria. The purpose of this study…”
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Linezolid absolute bioavailability and the effect of food on oral bioavailability by Welshman, Ian R., Sisson, Theresa A., Jungbluth, Gail L., Stalker, Dennis J., Hopkins, Nancy K.

“…Linezolid is a novel oxazolidinone antibiotic that has a spectrum of activity encompassing a variety of Gram‐positive bacteria. The objectives of this study…”
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Pharmacokinetics of Linezolid in Subjects with Renal Dysfunction by BRIER, Michael E, STALKER, Dennis J, ARUNOFF, George R, BATTS, Donald H, RYAN, Kristi K, O'GRADY, Margaret, HOPKINS, Nancy K, JUNGBLUTH, Gail L

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Pharmacokinetics and tolerance of single- and multiple-dose oral or intravenous linezolid, an oxazolidinone antibiotic, in healthy volunteers by Stalker, Dennis J., Jungbluth, Gail L., Hopkins, Nancy K., Batts, Donald H.

“…Aims: To determine the pharmacokinetics and tolerance of oral and intravenous linezolid, an oxazolidinone antibiotic, in healthy volunteers following single-…”
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Ceftriaxone disposition in open-heart surgery patients by JUNGBLUTH, G. L, PASKO, M. T, BEAM, T. R, JUSKO, W. J

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Dose-dependent pharmacokinetics of mezlocillin in rats by JUNGBLUTH, G. L, JUSKO, W. J

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Single dose pharmacokinetics of linezolid in infants and children by KEARNS, GREGORY L, ABDEL-RAHMAN, SUSAN M, BLUMER, JEFFREY L, REED, MICHAEL D, JAMES, LAURA P, JACOBS, RICHARD F, WELSHMAN, IAN R, JUNGBLUTH, GAIL L, STALKER, DENNIS J

“…BACKGROUND.Linezolid is an oxazolidinone antibiotic with excellent in vitro activity against a number of Gram-positive organisms including antibiotic-resistant…”
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Pharmacokinetics of ticarcillin and clavulanic acid (timentin) in relation to renal function by JUNGBLUTH, G. L, COOPER, D. L, DOYLE, G. D, CHUDZIK, G. M, JUSKO, W. J

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Ion-paired reversed-phase high-performance liquid chromatography assay for determination of ceftriaxone in human plasma and urine by Jungbluth, G L, Jusko, W J

“…A rapid, sensitive, and specific ion-paired reversed-phase HPLC assay for ceftriaxone in human plasma and urine is described. Small volumes (50 microL) of…”
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Clinical pharmacology of nicorandil in patients with congestive heart failure by Tice, F D, Jungbluth, G L, Binkley, P F, MacKichan, J J, Mohrland, J S, Wolf, D L, Leier, C V, Bindley, P F

“…Nicorandil is a nicotinamide derivative with a potential role in human therapeutics because of its potent vasodilating properties. The pharmacokinetics of oral…”
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Acute effects of increasing doses of nicorandil on renal function in man by Wolf, D L, Jungbluth, G L, Metzler, C M, Froeschke, M O, DeLoof, M J, Luderer, J R

“…The effects of nicorandil, a nicotinamide derived vasodilator combining nitrate and potassium channel opener actions, on kidney function have not been…”
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Factors affecting ceftriaxone plasma protein binding during open heart surgery by Jungbluth, G L, Pasko, M T, Jusko, W J

“…Factors most likely contributing to reduced ceftriaxone plasma protein binding in patients undergoing open heart surgery (OHS) were examined. Binding was…”
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Effect of formula feeding on oral absorption of caffeine in premature infants by Giacoia, G P, Jungbluth, G L, Jusko, W J

“…The systemic absorption of orally administered caffeine was evaluated in 16 premature infants receiving therapy for recurrent apnea. An oral bolus dose of…”
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Developmental pharmacokinetics of mezlocillin in 4 newborn infants by Jungbluth, G L, Wirth, Jr, F H, Rubio, T T, Janicke, D M, Jusko, W J

“…The disposition of mezlocillin was evaluated in 4 newborn infants in a sequential two-phase study at postnatal ages of 1 day and 8 or 10 days. Renal function…”
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Dose-related haemodynamic effects and pharmacokinetics of oral nicorandil in patients evaluated for chest pain by Arnold, J M, Kowey, P R, Wolf, D L, Jungbluth, G L, Hearron, A E, Luderer, J R

“…We studied the acute haemodynamic dose response of nicorandil, a combined nitrate and potassium channel opener, in patients evaluated for chest pain. Single…”
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Clinical pharmacokinetics of linezolid, a novel oxazolidinone antibacterial by STALKER, Dennis J, JUNGBLUTH, Gail L

“…Linezolid is the first antibacterial to be approved from the oxazolidinone class. The drug has substantial antimicrobial activity against Gram-positive…”
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Stereoselective binding of disopyramide to human plasma protein by Lima, J J, Jungbluth, G L, Devine, T, Robertson, L W

“…The binding of racemic disopyramide and its two enantiomers to protein were compared in two samples of human plasma, two samples of freshly drawn serum and in…”
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Pharmacokinetics of methylprednisolone sodium succinate and methylprednisolone in patients undergoing cardiopulmonary bypass by Kong, A N, Jungbluth, G L, Pasko, M T, Beam, T R, Jusko, W J

“…The pharmacokinetics of methylprednisolone sodium succinate (MPHS) and methylprednisolone (MP) were determined in six patients undergoing open heart surgery…”
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Application of real-time data assembly (RTDA) to a pivotal phase III pediatric trial: A proactive approach to population pharmacokinetic/pharmacodynamic (PK/PD) dataset creation by Rubino, C. M., McPhee, M., Vo, M., Jungbluth, G. L.

“…Clinical Pharmacology & Therapeutics (2003) 73, P65–P65; doi:…”
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