Search Results - "Jung-Cook"
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An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels
Published in Pharmacopsychiatry (01-03-2022)“…This international guideline proposes improving clozapine package inserts worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR)…”
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2
Giardia duodenalis: Flavohemoglobin is involved in drug biotransformation and resistance to albendazole
Published in PLoS pathogens (27-09-2022)“…Giardia duodenalis causes giardiasis, a major diarrheal disease in humans worldwide whose treatment relies mainly on metronidazole (MTZ) and albendazole (ABZ)…”
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3
Prefrontal and Striatal Gamma-Aminobutyric Acid Levels and the Effect of Antipsychotic Treatment in First-Episode Psychosis Patients
Published in Biological psychiatry (1969) (15-03-2018)“…Abnormally elevated levels of gamma-aminobutyric acid (GABA) in the medial prefrontal cortex (mPFC) have been reported in antipsychotic-free patients with…”
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4
Praziquanamine enantiomers: Crystal structure, Hirshfeld surface analysis, and quantum chemical studies
Published in Journal of molecular structure (05-07-2023)“…•A new methodology in the microwave-assisted acid hydrolysis of praziquanamides.•The enantiomers were characterized by X-ray crystallography, IR, UV, NMR, DSC…”
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5
Genomic Ancestry, CYP2D6, CYP2C9, and CYP2C19 Among Latin Americans
Published in Clinical pharmacology and therapeutics (01-01-2020)“…We present the distribution of CYP2D6, CYP2C9, and CYP2C19 variants and predicted phenotypes in 33 native and admixed populations from Ibero‐America…”
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6
Pharmacogenetics of adverse reactions to antiepileptic drugs
Published in Neurologia (Barcelona, Spain) (01-04-2018)“…Adverse drug reactions (ADRs) are a major public health concern and a leading cause of morbidity and mortality in the world. In the case of antiepileptic drugs…”
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Population pharmacokinetics of mycophenolic acid in adult kidney transplant patients under prednisone and tacrolimus regimen
Published in European journal of pharmaceutical sciences (01-07-2020)“…Mycophenolate mofetil (MMF) is typically used in combination with prednisone and tacrolimus to avoid graft rejection in kidney transplant patients. The aim of…”
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8
Pharmacokinetic variability of anthelmintics: implications for the treatment of neurocysticercosis
Published in Expert review of clinical pharmacology (01-01-2012)“…Human neurocysticercosis is a severe disease caused by the installation of Taenia solium larvae in the CNS. A wide variety of clinical manifestations are…”
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Pharmacokinetic Study of Intranasal Dexamethasone and Methylprednisolone Compared with Intravenous Administration: Two Open-Label, Single-Dose, Two-Period, Two-Sequence, Cross-Over Study in Healthy Volunteers
Published in Pharmaceutics (28-12-2022)“…Dexamethasone (DXM) and methylprednisolone (MEP) are potent glucocorticoids used to control several inflammatory conditions. Evidence of delayed DXM reaching…”
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10
Cysticidal activity of praziquantel-mebendazole combination: In vitro and in vivo studies
Published in Acta tropica (01-02-2020)“…•Praziquantel (PZQ) displays a sinergistic interaction with mebendazole (MBZ).•The combination exibited the cystidal effect in a shorter time than single…”
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11
Analysis of the effect of in vitro dissolution on the pharmacokinetics of albendazole
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2023)“…Albendazole is an anthelmintic drug commonly used in parenchymal neurocysticercosis and cystic echinococcosis. The aim of this study was to explore whether…”
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12
Melatonin in Combination with Albendazole or Albendazole Sulfoxide Produces a Synergistic Cytotoxicity against Malignant Glioma Cells through Autophagy and Apoptosis
Published in Brain sciences (27-05-2023)“…Glioblastoma is the most aggressive and lethal brain tumor in adults, presenting diffuse brain infiltration, necrosis, and drug resistance. Although new drugs…”
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13
CYP2C9, CYP2C19, ABCB1 genetic polymorphisms and phenytoin plasma concentrations in Mexican-Mestizo patients with epilepsy
Published in The pharmacogenomics journal (01-06-2016)“…We aimed to explore the possible influence of CYP2C9 ( *2, *3 and IVS8-109 A>T), CYP2C19 ( *2 , *3 and *17 ) and ABCB1 (1236C>T, 2677G>A/T and 3435C>T) on…”
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14
Population Pharmacokinetics of Sertraline in Psychiatric and Substance Use Disorders
Published in Journal of clinical pharmacology (01-10-2024)“…This study aimed to characterize the population pharmacokinetics of sertraline in Mexican patients with psychiatric and substance use disorders. Fifty‐nine…”
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15
Evaluation of New Benzimidazole Derivatives as Cysticidal Agents: In Vitro, in Vivo and Docking Studies
Published in Chemical & pharmaceutical bulletin (01-12-2019)“…Based on our previous research on cysticidal drugs, we report the synthesis and evaluation of three new benzimidazole derivatives. In these compounds, the…”
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In vitro and in vivo cysticidal activity of extracts and isolated flavanone from the bark of Prunus serotina: A bio-guided study
Published in Acta tropica (01-06-2017)“…The present paper reports the activity of Prunus serotina against Taenia crassiceps cysts and the isolation and identification of naringenin as the main active…”
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17
Distribution of Hydroxychloroquine in Lymphoid Tissue in a Rabbit Model for HIV Infection
Published in Antimicrobial Agents and Chemotherapy (01-01-2014)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Population pharmacokinetics of rifampicin in Mexican patients with tuberculosis
Published in Journal of clinical pharmacy and therapeutics (01-02-2013)“…Summary What is known and Objective: Rifampicin (RIF) shows wide variability in its pharmacokinetics. The purpose of this study was to develop and validate a…”
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Relative bioavailability of rifampicin in a three-drug fixed-dose combination formulation
Published in The international journal of tuberculosis and lung disease (01-11-2010)“…SETTING: In a previous monitoring study of rifampicin (RMP) in tuberculosis (TB) patients treated with a generic formulation of a three-drug fixed-dose…”
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Murine cysticercosis model: Influence of the infection time and the time of treatment on the cysticidal efficacy of albendazole and praziquantel
Published in Experimental parasitology (01-02-2015)“…•There is a strong dependence between the experimental variables and the efficacy.•The best time to start the drug treatment is 10 days post-infection.•A…”
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