Search Results - "Jung, Youngeun"

Global profiling of distinct cysteine redox forms reveals wide-ranging redox regulation in C. elegans by Meng, Jin, Fu, Ling, Liu, Keke, Tian, Caiping, Wu, Ziyun, Jung, Youngeun, Ferreira, Renan B., Carroll, Kate S., Blackwell, T. Keith, Yang, Jing

“…Post-translational changes in the redox state of cysteine residues can rapidly and reversibly alter protein functions, thereby modulating biological processes…”
Get full text

Deformylative Intramolecular Hydroarylation: Synthesis of Benzo[e]pyrido[1,2‑a]indoles by Jung, Youngeun, Kim, Ikyon

“…Attempted cyclization of indolizines bearing both formyl and alkyne groups under acid catalysis provided benzo­[e]­pyrido­[1,2-a]­indoles with an aryl…”
Get full text

Chemical proteomics reveals new targets of cysteine sulfinic acid reductase by Akter, Salma, Fu, Ling, Jung, Youngeun, Conte, Mauro Lo, Lawson, J. Reed, Lowther, W. Todd, Sun, Rui, Liu, Keke, Yang, Jing, Carroll, Kate S.

“…Cysteine sulfinic acid or S -sulfinylation is an oxidative post-translational modification (OxiPTM) that is known to be involved in redox-dependent regulation…”
Get full text

Reaction-based fluorogenic probes for detecting protein cysteine oxidation in living cells by Ferreira, Renan B., Fu, Ling, Jung, Youngeun, Yang, Jing, Carroll, Kate S.

“…‘Turn-on’ fluorescence probes for detecting H 2 O 2 in cells are established, but equivalent tools to monitor the products of its reaction with protein…”
Get full text

A concise synthetic approach to brazilin via Pd-catalyzed allylic arylation by Jung, Youngeun, Kim, Ikyon

“…A short synthetic route to the trimethyl ether of brazilin was developed in 6 steps from 7-methoxychromene with 78% overall yield. Regioselective installation…”
Get more information

Author Correction: Reaction-based fluorogenic probes for detecting protein cysteine oxidation in living cells by Ferreira, Renan B., Fu, Ling, Jung, Youngeun, Yang, Jing, Carroll, Kate S.

Get full text

Syntheses of pterocarpenes and coumestans via regioselective cyclodehydration by Nayak, Maloy, Jung, Youngeun, Kim, Ikyon

“…A highly efficient synthetic route to pterocarpenes and coumestans is described. BCl3-mediated dehydrative cyclization of 1,3-diaryloxyacetones under mild…”
Get more information

Symmetry-based approach to oligostilbenoids: Rapid entry to viniferifuran, shoreaphenol, malibatol A, and diptoindonesin G by Jung, Youngeun, Singh, Dileep Kumar, Kim, Ikyon

“…The recognition of the local symmetric image within benzofuran-based natural oligostilbenoids guided us to design a modular synthetic approach to these…”
Get full text

Synthesis of 6-Aryl-5-iodobenzo[e]pyrido[1,2-a]indoles by 6-endo-dig Iodocyclization by Jung, Youngeun, Kim, Ikyon

“…Regioselective access to 6‐aryl‐5‐iodobenzo[e]pyrido[1,2‐a]indoles was realized by using a facile 6‐endo‐dig iodine‐mediated cyclization under mild reaction…”
Get full text

Endogenous SO2-dependent Smad3 redox modification controls vascular remodeling by Huang, Yaqian, Li, Zongmin, Zhang, Lulu, Tang, Huan, Zhang, Heng, Wang, Chu, Chen, Selena Ying, Bu, Dingfang, Zhang, Zaifeng, Zhu, Zhigang, Yuan, Piaoliu, Li, Kun, Yu, Xiaoqi, Kong, Wei, Tang, Chaoshu, Jung, Youngeun, Ferreira, Renan B., Carroll, Kate S., Du, Junbao, Yang, Jing, Jin, Hongfang

“…Sulfur dioxide (SO2) has emerged as a physiological relevant signaling molecule that plays a prominent role in regulating vascular functions. However,…”
Get full text

Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models by Lee, Hee Yang, Yoon, Soljee, Lee, Jeong Hwa, Park, Keunwan, Jung, Youngeun, Cho, Illhwan, Lee, Donghee, Shin, Jisu, Kim, Kyeonghwan, Kim, Sunmi, Kim, Jimin, Kim, Koeun, Han, Seung Hoon, Kim, Seong Muk, Kim, Hye Ju, Kim, Hye Yun, Kim, Ikyon, Kim, Young Soo

“…Aggregated amyloid-β (Aβ) is considered a pathogenic initiator of Alzheimer's disease (AD), in strong association with tau hyperphosphorylation,…”
Get full text

Total Synthesis of Brazilin by Jung, Youngeun, Kim, Ikyon

“…Described herein is a highly efficient total synthesis of brazilin from commercially available starting materials in 9 steps with 70% overall yield. Mitsunobu…”
Get full text

Domino Knoevenagel Condensation/Intramolecular Aldol Cyclization Route to Diverse Indolizines with Densely Functionalized Pyridine Units by Kim, Myungock, Jung, Youngeun, Kim, Ikyon

“…A highly efficient [4 + 2] annulation route to polysubstituted indolizines is described employing a domino Knoevenagel condensation/intramolecular aldol…”
Get full text

Facile approach to diverse 3-acylated indolizines via a sequential Sonogashira coupling/iodocyclization process by Jung, Youngeun, Kim, Ikyon

“…Successful implementation of a sequential Pd-catalyzed Sonogashira cross-coupling/iodine-promoted 5-exo-dig cyclization procedure with pyridines bearing a…”
Get full text

Diversity-oriented decoration of pyrrolo[1,2-a]pyrazines by Park, Sujin, Jung, Youngeun, Kim, Ikyon

“…Diversity-oriented synthesis of a chemical library based on a pyrrolo[1,2-a]pyrazine core is described by using palladium-catalyzed direct C6 arylation of…”
Get full text

Chaperone-directed ribosome repair after oxidative damage by Yang, Yoon-Mo, Jung, Youngeun, Abegg, Daniel, Adibekian, Alexander, Carroll, Kate S., Karbstein, Katrin

“…Because of the central role ribosomes play for protein translation and ribosome-mediated mRNA and protein quality control (RQC), the ribosome pool is surveyed…”
Get full text

Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration by Zivanovic, Jasmina, Kouroussis, Emilia, Kohl, Joshua B., Adhikari, Bikash, Bursac, Biljana, Schott-Roux, Sonia, Petrovic, Dunja, Miljkovic, Jan Lj, Thomas-Lopez, Daniel, Jung, Youngeun, Miler, Marko, Mitchell, Sarah, Milosevic, Verica, Gomes, Jose Eduardo, Benhar, Moran, Gonzalez-Zorn, Bruno, Ivanovic-Burmazovic, Ivana, Torregrossa, Roberta, Mitchell, James R., Whiteman, Matthew, Schwarz, Guenter, Snyder, Solomon H., Paul, Bindu D., Carroll, Kate S., Filipovic, Milos R.

“…Life on Earth emerged in a hydrogen sulfide (H2S)-rich environment eons ago and with it protein persulfidation mediated by H2S evolved as a signaling…”
Get full text

Mitochondria-targeting indolizino[3,2-c]quinolines as novel class of photosensitizers for photodynamic anticancer activity by Kwon, Soonbum, Lee, Yeongcheol, Jung, Youngeun, Kim, Ju Hee, Baek, Byungyeob, Lim, Bumhee, Lee, Jungeun, Kim, Ikyon, Lee, Jeeyeon

“…To achieve efficient photodynamic activity, substantial effort has been dedicated to precise control of the intracellular localization of current…”
Get full text

Catalyst-free synthesis of 4-alkynylazobenzenes from quinols by Yoon, Sukhyun, Jung, Youngeun, Kim, Ikyon

“…[Display omitted] •Azoaromatic compounds received much attention due to their photoisomerization capability.•Highly conjugated 4-alkynylazoaromatic compounds…”
Get full text

Nucleophilic covalent ligand discovery for the cysteine redoxome by Fu, Ling, Jung, Youngeun, Tian, Caiping, Ferreira, Renan B., Cheng, Ruifeng, He, Fuchu, Yang, Jing, Carroll, Kate S.

“…With an eye toward expanding chemistries used for covalent ligand discovery, we elaborated an umpolung strategy that exploits the ‘polarity reversal’ of sulfur…”
Get full text