Search Results - "Jung, Sara"

Targeting heterogeneity of adrenocortical carcinoma: Evaluation and extension of preclinical tumor models to improve clinical translation by Hantel, Constanze, Shapiro, Igor, Poli, Giada, Chiapponi, Costanza, Bidlingmaier, Martin, Reincke, Martin, Luconi, Michaela, Jung, Sara, Beuschlein, Felix

“…In recent years it has been recognized that clinical translation of novel therapeutic strategies for patients with adrenocortical carcinoma (ACC) often fails…”
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PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome by Vetrivel, Sharmilee, Tamburello, Mariangela, Oßwald, Andrea, Zhang, Ru, Khan, Ali, Jung, Sara, Baker, Jessica E, Rainey, William E, Nowak, Elisabeth, Altieri, Barbara, Detomas, Mario, Watts, Deepika, Williams, Tracy Ann, Wielockx, Ben, Beuschlein, Felix, Reincke, Martin, Sbiera, Silviu, Riester, Anna

“…We performed a transcriptomic analysis of adrenal signaling pathways in various forms of endogenous Cushing's syndrome (CS) to define areas of dysregulated and…”
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Liposomal polychemotherapy improves adrenocortical carcinoma treatment in a preclinical rodent model by Hantel, Constanze, Jung, Sara, Mussack, Thomas, Reincke, Martin, Beuschlein, Felix

“…Owing to high relapse rates and early metastatic spread, prognosis in adrenocortical carcinoma (ACC) patients remains poor, highlighting the importance of…”
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Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo by Hasanovic, Anida, Ruggiero, Carmen, Jung, Sara, Rapa, Ida, Signetti, Laurie, Ben Hadj, Monia, Terzolo, Massimo, Beuschlein, Felix, Volante, Marco, Hantel, Constanze, Lalli, Enzo, Mus‐Veteau, Isabelle

“…One of the crucial challenges in the clinical management of cancer is the resistance to chemotherapeutics. We recently demonstrated that the Hedgehog receptor…”
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Preclinical progress and first translational steps for a liposomal chemotherapy protocol against adrenocortical carcinoma by Jung, Sara, Nagy, Zoltan, Fassnacht, Martin, Zambetti, Gerard, Weiss, Max, Reincke, Martin, Igaz, Peter, Beuschlein, Felix, Hantel, Constanze

“…Systemic therapy of adrenocortical carcinoma (ACC) is limited by heterogeneous tumor response and adverse effects. Recently, we demonstrated anti-tumor…”
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Photon TMDs from uPDFevolv by Jung, Hannes, Taheri Monfared, Sara, Wening, Thomas

“…We present photon TMDs generated using the Parton Branching Method with QED evolution. We discuss the TMD's properties and compare it to the gluon TMD. Two…”
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Multicenter Comparison of the Safety and Efficacy of Clopidogrel Versus Ticagrelor for Neuroendovascular Stents by May, Casey C., Holden, Devin, Robbins, Blake T., Cook, Aaron M., Jung, Sara, Smetana, Keaton S., Roels, Christina, Harlan, Sara Schuman, Keegan, Shaun, Brophy, Gretchen, Al Mohaish, Sulaiman, Sandler, Melissa, Spetz, Samantha, Wohlfarth, Kevin, Owusu-Guha, Jocelyn, Buschur, Pamela, Hetrick, Elizabeth, Dombrowski, Keith, Glover, Jennifer, Levesque, Melissa, Dingman, Spencer, Hussain, Mohammed

“…Background Dual antiplatelet therapy (DAPT) is commonly employed for neuroendovascular stenting due to the significant risk of thromboembolism. Clopidogrel and…”
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Multicenter comparison of antiplatelet treatment strategies for urgent/emergent neuroendovascular stenting by Holden, Devin, May, Casey C., Robbins, Blake T., Cook, Aaron M., Jung, Sara, Smetana, Keaton S., Roels, Christina, Harlan, Sara Schuman, Keegan, Shaun, Brophy, Gretchen, Al Mohaish, Sulaiman, Sandler, Melissa, Spetz, Samantha, Wohlfarth, Kevin, Owusu-Guha, Jocelyn, Buschur, Pamela, Hetrick, Elizabeth, Dombrowski, Keith, Glover, Jennifer, Levesque, Melissa, Dingman, Spencer, Hussain, Mohammed

“…Background Emergent neuroendovascular stenting presents challenges for the utilization of antiplatelet agents. Methods This was a multicenter, retrospective…”
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IGF1-R inhibition and liposomal doxorubicin: Progress in preclinical evaluation for the treatment of adrenocortical carcinoma by Beuschlein, Felix, Jakoby, Judith, Mentz, Susanne, Zambetti, Gerard, Jung, Sara, Reincke, Martin, Süss, Regine, Hantel, Constanze

“…Adrenocortical carcinoma (ACC) is a tumor with poor prognosis and limited therapeutic options. Therefore, in addition to multi-chemotherapeutic regimens IGF-1…”
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