Search Results - "Jung, Sang‐Hyuk"
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Leonurus sibiricus L. ethanol extract promotes osteoblast differentiation and inhibits osteoclast formation
Published in International journal of molecular medicine (01-09-2019)“…Leonurus sibiricus L. (LS) is a medicinal plant used in East Asia, Europe and the USA. LS is primarily used in the treatment of gynecological diseases, and…”
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2
Dendrobium nobile Lindley Administration Attenuates Atopic Dermatitis-like Lesions by Modulating Immune Cells
Published in International journal of molecular sciences (18-04-2022)“…Atopic dermatitis (AD) is a chronic inflammatory skin disease that can significantly affect daily life by causing sleep disturbance due to extreme itching. In…”
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3
Persicae Semen Promotes Bone Union in Rat Fractures by Stimulating Osteoblastogenesis through BMP-2 and Wnt Signaling
Published in International journal of molecular sciences (01-04-2023)“…Fractures cause extreme pain to patients and impair movement, thereby significantly reducing their quality of life. However, in fracture patients, movement of…”
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4
Large-scale cross-ancestry genome-wide meta-analysis of serum urate
Published in Nature communications (24-04-2024)“…Hyperuricemia is an essential causal risk factor for gout and is associated with cardiometabolic diseases. Given the limited contribution of East Asian…”
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Novel polygenic risk score approach with transcriptome‐based weighting for genetic risk prediction of late‐onset Alzheimer’s disease
Published in Alzheimer's & dementia (01-12-2021)“…Background Recent genetic studies showed that polygenic risk score (PRS) could be used to identify individuals at high risk of Alzheimer's disease (AD)…”
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Association of glaucoma and lifestyle with incident cardiovascular disease: a longitudinal prospective study from UK Biobank
Published in Scientific reports (15-02-2023)“…The shared pathophysiological features of the cerebrovascular disease (CVD) and glaucoma suggest an association between the two diseases. Using the prospective…”
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Polygenic risk for type 2 diabetes, lifestyle, metabolic health, and cardiovascular disease: a prospective UK Biobank study
Published in Cardiovascular diabetology (14-07-2022)“…Few studies have examined associations between genetic risk for type 2 diabetes (T2D), lifestyle, clinical risk factors, and cardiovascular disease (CVD). We…”
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Association between genetic risk and adherence to healthy lifestyle for developing age-related hearing loss
Published in BMC medicine (26-03-2024)“…Previous studies have shown that lifestyle/environmental factors could accelerate the development of age-related hearing loss (ARHL). However, there has not…”
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Impacts of gender and lifestyle on the association between depressive symptoms and cardiovascular disease risk in the UK Biobank
Published in Scientific reports (04-07-2023)“…We investigated the effects of gender and lifestyle on the association between frequency of depressive symptoms and CVD risk. The UK Biobank is a national…”
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10
The anti-obesity effect of mulberry leaf (Mori Folium) extracts was increased by bioconversion with Pectinex
Published in Scientific reports (27-11-2022)“…Mulberry leaf ( Mori Folium ) extract (MLE) is known to have anti-obesity effects. In this study, the enhanced effects of MLE after bioconversion treatment…”
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Albiflorin Promotes Osteoblast Differentiation and Healing of Rat Femoral Fractures Through Enhancing BMP-2/Smad and Wnt/β-Catenin Signaling
Published in Frontiers in pharmacology (16-07-2021)“…Fracture healing is related to osteogenic differentiation and mineralization. Recently, due to the unwanted side effects and clinical limitations of existing…”
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12
Polygenic risk score-based phenome-wide association study of head and neck cancer across two large biobanks
Published in BMC medicine (14-03-2024)“…Numerous observational studies have highlighted associations of genetic predisposition of head and neck squamous cell carcinoma (HNSCC) with diverse risk…”
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13
The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41
Published in PloS one (01-04-2014)“…Since insulin resistance can lead to hyperglycemia, improving glucose uptake into target tissues is critical for regulating blood glucose levels. Among the…”
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14
Leveraging genetic overlap between irritability and psychiatric disorders to identify genetic variants of major psychiatric disorders
Published in Experimental & molecular medicine (01-06-2023)“…Irritability is a heritable core mental trait associated with several psychiatric illnesses. However, the genomic basis of irritability is unclear. Therefore,…”
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Effects of Sparganii Rhizoma on Osteoclast Formation and Osteoblast Differentiation and on an OVX-Induced Bone Loss Model
Published in Frontiers in pharmacology (04-01-2022)“…Postmenopausal osteoporosis is caused by an imbalance between osteoclasts and osteoblasts and causes severe bone loss. Osteoporotic medicines are classified…”
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Effect of Taraxaci Herba on Bone Loss in an OVX-Induced Model through the Regulation of Osteoclast Differentiation
Published in Nutrients (18-10-2022)“…Bone is a dynamic tissue that maintains homeostasis with a balance of osteoclasts for bone resorption and osteoblasts for bone formation. Women are deficient…”
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NETMAGE: A human disease phenotype map generator for the network-based visualization of phenome-wide association study results
Published in Gigascience (15-02-2022)“…Abstract Background Disease complications, the onset of secondary phenotypes given a primary condition, can exacerbate the long-term severity of outcomes…”
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Dolichos Lablab Linné Inhibits Bone Density Loss and Promotes Bone Union in Senile Osteoporosis through Osteogenesis
Published in Pharmaceuticals (Basel, Switzerland) (25-09-2023)“…As populations continue to age, osteoporosis has emerged as an increasingly critical concern. Most advancements in osteoporosis treatment are predominantly…”
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Polygenic risk score-based phenome-wide association for glaucoma and its impact on disease susceptibility in two large biobanks
Published in Journal of translational medicine (15-04-2024)“…Glaucoma is a leading cause of worldwide irreversible blindness. Considerable uncertainty remains regarding the association between a variety of phenotypes and…”
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20
Change in the pH of NaI and methyl alkyl ketone solutions under gamma irradiation
Published in Journal of radioanalytical and nuclear chemistry (01-10-2020)“…The effects of dissolved chemicals such as NaOH, NaI, methyl ethyl ketone (MEK), and methyl isobutyl ketone (MIBK) on solution pH after gamma irradiation were…”
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