Search Results - "Jung, Kyung‐Hee"
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Systemic and Local Metabolic Alterations in Sleep-Deprivation-Induced Stress: A Multiplatform Mass-Spectrometry-Based Lipidomics and Metabolomics Approach
Published in Journal of proteome research (06-09-2019)“…Sleep deprivation (SD) is known to be associated with metabolic disorders and chronic diseases. Complex metabolic alterations induced by SD at omics scale and…”
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Citrus unshiu peel extract ameliorates hyperglycemia and hepatic steatosis by altering inflammation and hepatic glucose- and lipid-regulating enzymes in db/db mice
Published in The Journal of nutritional biochemistry (01-02-2013)“…Insulin resistance in Type 2 diabetes leads to hepatic steatosis that can accompanied by progressive inflammation of the liver. Citrus unshiu peel is a rich…”
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Acetyl-CoA synthetase 2 contributes to a better prognosis for liver cancer by switching acetate-glucose metabolism
Published in Experimental & molecular medicine (01-03-2024)“…Acetyl-CoA synthetase 2 (ACSS2)-dependent acetate usage has generally been associated with tumorigenesis and increased malignancy in cancers under…”
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Melatonin Synergizes with Sorafenib to Suppress Pancreatic Cancer via Melatonin Receptor and PDGFR-β/STAT3 Pathway
Published in Cellular physiology and biochemistry (01-01-2018)“…Background/Aims: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant tumors with poor prognosis. Conventional chemotherapies including…”
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KCTD17-mediated Ras stabilization promotes hepatocellular carcinoma progression
Published in Clinical and molecular hepatology (01-10-2024)“…Background/Aims: Potassium channel tetramerization domain containing 17 (KCTD17) protein, an adaptor for the cullin3 (Cul3) ubiquitin ligase complex, has been…”
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Effect of sodium fluoride on the virulence factors and composition of Streptococcus mutans biofilms
Published in Archives of oral biology (01-07-2011)“…Abstract Objective This study aimed to evaluate the influence of NaF (2, 10, 50 and 125 ppm F− ) on the virulence factors and composition of Streptococcus…”
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SB365 inhibits angiogenesis and induces apoptosis of hepatocellular carcinoma through modulation of PI3K/Akt/mTOR signaling pathway
Published in Cancer science (01-11-2012)“…Identification of small molecules that safely inhibit cancer progression is critical for cancer therapeutics. Saponins exhibit cytostatic and cytotoxic…”
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Protective Effect of Tanshinone IIA on the Early Stage of Experimental Diabetic Nephropathy
Published in Biological & Pharmaceutical Bulletin (01-02-2009)“…Diabetic nephropathy (DN) has become the leading cause of end stage renal failure, and prevention or retardation of DN has become a major goal in biomedical…”
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Comparison of Prevalence- and Smoking Impact Ratio-Based Methods of Estimating Smoking-Attributable Fractions of Deaths
Published in Journal of epidemiology (2016)“…Smoking is a major modifiable risk factor for premature mortality. Estimating the smoking-attributable burden is important for public health policy. Typically,…”
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Amygdalin inhibits genes related to cell cycle in SNU-C4 human colon cancer cells
Published in World journal of gastroenterology : WJG (07-09-2005)“…AIM: The genes were divided into seven categories according to biological function; apoptosis-related, immune response-related, signal transduction-related,…”
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Suppression by Fucoidan of Liver Fibrogenesis via the TGF-β/Smad Pathway in Protecting against Oxidative Stress
Published in Bioscience, biotechnology, and biochemistry (2011)“…Fucoidan, a sulfated polysaccharide extracted from various types of brown seaweed, possesses a wide range of pharmacological properties. We investigated the…”
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Morin protects acute liver damage by carbon tetrachloride (CCl4) in rat
Published in Archives of pharmacal research (01-09-2008)“…The purpose of this study was to investigate possible beneficial effects of morin on CCl 4 -induced acute hepatotoxicity in rats. Rats received a single dose…”
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effect of granule surface area on hydrolysis of native starches by pullulanase
Published in Die Stärke (01-09-2013)“…Various native starch granules were reacted as substrates for a debranching enzyme, pullulanase, from Bacillus acidopullulyticus, and the kinetic mechanism was…”
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Selonsertib Inhibits Liver Fibrosis via Downregulation of ASK1/ MAPK Pathway of Hepatic Stellate Cells
Published in Biomolecules & therapeutics (01-11-2020)“…Liver fibrosis constitutes a significant health problem worldwide due to its rapidly increasing prevalence and the absence of specific and effective…”
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Verticinone induces cell cycle arrest and apoptosis in immortalized and malignant human oral keratinocytes
Published in Phytotherapy research (01-03-2008)“…Although verticinone, a major alkaloid isolated from the bulbus of Fritillaria ussuriensis, has been shown to induce differentiation in human leukemia cells,…”
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Combination Therapy of the Active KRAS-Targeting Antibody inRas37 and a PI3K Inhibitor in Pancreatic Cancer
Published in Biomolecules & therapeutics (01-05-2022)“…KRAS activating mutations, which are present in more than 90% of pancreatic cancers, drive tumor dependency on the RAS/mitogen-activated protein kinase (MAPK)…”
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Characteristics of Morphological Changes in Fins according to Larval Growth of Red Spotted Grouper, Epinephelus akaara
Published in Balsaeng'gwa saengsig (01-09-2024)“…This study investigated the fin development and morphological characteristics according to larval growth in order to obtain information on behavioral…”
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Tumor vessel normalization by the PI3K inhibitor HS-173 enhances drug delivery
Published in Cancer letters (10-09-2017)“…Tumor vessels are leaky and immature, which causes poor oxygen and nutrient supply to tumor vessels and results in cancer cell metastasis to distant organs…”
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Suppressive Effect of Punica granatum on the Production of Tumor Necrosis Factor (Tnf) in BV2 Microglial Cells
Published in Biological & Pharmaceutical Bulletin (01-06-2006)“…While the anti-oxidant properties of Punica granatum methanol extract (PGMF) are well documented, little is known concerning the anti-inflammatory effect of…”
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Potential role of ANGPTL4 in cancer progression, metastasis, and metabolism: a brief review
Published in BMB reports (01-08-2024)“…Angiopoietin-like 4 (ANGPTL4) has been identified as an adipokine involved in several non-metabolic and metabolic diseases, including angiogenesis, glucose…”
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