Search Results - "Jung, Kyeong Eun"
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Transvascular delivery of small interfering RNA to the central nervous system
Published in Nature (05-07-2007)“…A major impediment in the treatment of neurological diseases is the presence of the blood-brain barrier, which precludes the entry of therapeutic molecules…”
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Galactosylated Lipidoid Nanoparticles for Delivery of Small Interfering RNA to Inhibit Hepatitis C Viral Replication In Vivo
Published in Advanced healthcare materials (01-11-2016)“…Small interfering RNA (siRNA) delivery can provide an effective therapy for treating viral diseases by silencing genes involved in viral replication. In this…”
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3
Avoiding High‐Pressure Problem for Modified RNA‐attached Polystyrene Support by Pre‐Swelling Using Toluene in the Oligonucleotide Synthesis
Published in Bulletin of the Korean Chemical Society (01-10-2021)“…This study describes a method to avoid the high‐pressure problem caused by swelling during the detritylation step in oligonucleotide solid‐phase synthesis…”
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4
Azasugar-Containing Phosphorothioate Oligonucleotide (AZPSON) DBM-2198 Inhibits Human Immunodeficiency Virus Type 1 (HIV-1) Replication by Blocking HIV-1 gp120 without Affecting the V3 Region
Published in Molecules and cells (2015)“…DBM-2198, a six-membered azasugar nucleotide (6-AZN)-containing phosphorothioate (P = S) oligonucleotide (AZPSON), was described in our previous publication…”
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5
Newly Designed Six-Membered Azasugar Nucleotide-Containing Phosphorothioate Oligonucleotides as Potent Human Immunodeficiency Virus Type 1 Inhibitors
Published in Antimicrobial Agents and Chemotherapy (01-10-2005)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Analysis and Purification of Synthetic Nucleic Acids Using HPLC
Published in Current protocols in nucleic acid chemistry (01-06-2015)“…Chromatographic methods have been essential tools for analysis and purification of synthetic oligonucleotides since the 1970s. Significant developments in…”
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7
Human Noxin is an anti‐apoptotic protein in response to DNA damage of A549 non‐small cell lung carcinoma
Published in International journal of cancer (01-06-2014)“…Human Noxin (hNoxin, C11Orf82), a homolog of mouse noxin, is highly expressed in colorectal and lung cancer tissues. hNoxin contains a DNA‐binding C‐domain in…”
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OIP5 is a highly expressed potential therapeutic target for colorectal and gastric cancers
Published in BMB reports (30-05-2010)“…Previously, we reported that overexpression of Opa (Neisseria gonorrhoeae opacity-associated)-interacting protein 5 (OIP5) caused multi-septa formation and…”
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OIP5 is a highly expressed potential therapeutic target for colorectal and gastric cancers
Published in BMB reports (01-05-2010)“…Previously, we reported that overexpression of Opa (Neisseria gonorrhoeae opacity-associated)-interacting protein 5 (OIP5) caused multi-septa formation and…”
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10
Azasugar-Containing Phosphorothioate Oligonucleotide (AZPSON) DBM-2198 Inhibits Human Immunodeficiency Virus Type 1 (HIV-1) Replication by Blocking HIV-1 gp120 without Affecting the V3 Region
Published in Molecules and cells (01-02-2015)“…DBM-2198, a six-membered azasugar nucleotide (6-AZN)- containing phosphorothioate (P = S) oligonucleotide (AZPSON), was described in our previous publication…”
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11
Data on the transcriptional regulation of DNA damage induced apoptosis suppressor (DDIAS) by ERK5/MEF2B pathway in lung cancer cells
Published in Data in brief (01-12-2016)“…The data included in this article are associated with the article entitled “DNA-damage-induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B…”
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2',5'-DNA Containing Guanine and Cytosine Forms Stable Duplexes
Published in Journal of the American Chemical Society (01-07-1994)Get full text
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Synthesis and Activity of a Potent ${\alpha}$-glucosidase inhibitor, (1R, 6R, 8S)-cis-1,6-dihydroxypyrrolizidine, and its isomer
Published in Archives of pharmacal research (1997)“…The synthesis of cis- and trans-1,6-dihydroxypyrrolizidine starting from trans-4-hydroxy-L-proline and their evaluation as glycosidase inhibitors are reported…”
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Korea National Health and Nutrition Examination Survey, 20th Anniversary: Accomplishments and future directions
Published in Epidemiology and health (19-04-2021)“…The Korea National Health and Nutrition Examination Survey (KNHANES) was initiated in 1998 to provide evidence for the development and evaluation of health…”
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2',5'-DNA containing guanine and cytosine forms stable duplexes
Published in Journal of the American Chemical Society (1994)“…2',5'-Linked DNA oligomers bearing the bases guanine and cytosine are found to associate. Three 2',5'-DNA strands composed entirely of the bases guanine and…”
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Structural Study of Antisense Dimers , Modified Adenosine - Thymidine Phosphorothioate
Published in Journal of microbiology and biotechnology (01-12-2000)“…Antisense molecules are structurally simple linear oligomers of nucleotides. They can recognize a complementary sequence by base pairing, therefore, antisense…”
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DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cells
Published in Oncogene (01-03-2018)“…DNA damage-induced apoptosis suppressor (DDIAS) has an anti-apoptotic function during DNA damage in lung cancer. However, the anti-apoptotic mechanism of DDIAS…”
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DNA with 2'-5' Phosphodiester Bonds Forms a Duplex Structure in the A-type Conformation
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DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes β-catenin-mediated invasion
Published in Biochimica et biophysica acta (01-11-2016)“…DNA damage induced apoptosis suppressor (DDIAS) is an anti-apoptotic protein that promotes cancer cell survival. We previously reported that DDIAS is…”
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Synthesis and hybridization properties of oligonucleotides containing 6-membered azasugar nucleotides
Published in Bioorganic & medicinal chemistry letters (20-12-1999)“…A modified nucleoside was synthesized with adenine and a 6-membered azasugar, and it was converted to the phosphoramidite which was used for the incorporation…”
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