Search Results - "Jung, Jong Gab"
-
1
Establishment of a Serum-Free Hepatocyte Cryopreservation Process for the Development of an "Off-the-Shelf" Bioartificial Liver System
Published in Bioengineering (Basel) (29-11-2022)“…To use hepatocytes immediately when necessary for hepatocyte transplantation and bioartificial liver (BAL) systems, a serum-free cryopreservation protocol…”
Get full text
Journal Article -
2
Selecting serum-free hepatocyte cryopreservation stage and storage temperature for the application of an “off-the-shelf” bioartificial liver system
Published in Scientific reports (28-05-2024)“…The bioartificial liver (BAL) system can potentially rescue acute liver failure (ALF) patients by providing partial liver function until a suitable donor liver…”
Get full text
Journal Article -
3
TM-25659-Induced Activation of FGF21 Level Decreases Insulin Resistance and Inflammation in Skeletal Muscle via GCN2 Pathways
Published in Molecules and cells (2015)“…The TAZ activator 2-butyl-5-methyl-6-(pyridine-3-yl)-3-[2'-(1H-tetrazole-5-yl)-biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine] (TM-25659) inhibits adipocyte…”
Get full text
Journal Article -
4
Involvement of iron depletion in palmitate-induced lipotoxicity of beta cells
Published in Molecular and cellular endocrinology (15-05-2015)“…•Palmitate treatment reduced the level of transferrin receptor 1 in INS-1 beta cells.•Palmitate treatment reduced labile iron pool in INS-1 cells.•Iron…”
Get full text
Journal Article -
5
Association between insulin resistance and impairment of FGF21 signal transduction in skeletal muscles
Published in Endocrine (01-07-2016)“…Fibroblast growth factor (FGF) 21, was identified as a potent metabolic regulator of glucose and lipid metabolism. We investigated whether the levels and…”
Get full text
Journal Article -
6
Phase 1/2a Trial of a Bioartificial Liver Support System (LifeLiver) for Acute Liver Failure Patients
Published in Transplantation (01-07-2018)“…Bioartificial liver (BAL) support offers a potential means of improving survival of acute liver failure (ALF) patients by providing partial liver function…”
Get full text
Journal Article -
7
IL-6 induction of TLR-4 gene expression via STAT3 has an effect on insulin resistance in human skeletal muscle
Published in Acta diabetologica (01-04-2013)“…We investigated the cytokines and mechanisms involved in the induction of insulin resistance in human skeletal muscle. Ten subjects with impaired glucose…”
Get full text
Journal Article -
8
TM-25659-Induced Activation of FGF21 Level Decreases Insulin Resistance and Inflammation in Skeletal Muscle via GCN2 Pathways
Published in Molecules and cells (01-12-2015)“…The TAZ activator 2-butyl-5-methyl-6-(pyridine-3-yl)-3-[2'-(1H-tetrazole-5-yl)-biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine] (TM-25659) inhibits adipocyte…”
Get full text
Journal Article -
9
A compound (DW1182v) protecting high glucose/palmitate-induced glucolipotoxicity to INS-1 beta cells preserves islet integrity and improves hyperglycemia in obese db/db mouse
Published in European journal of pharmacology (05-12-2012)“…Loss of beta cells is a pathogenic cause for the development of type 2 diabetes. High glucose/free fatty acid (HG/FFA)-induced glucolipotoxicity was thought to…”
Get full text
Journal Article -
10
Glutamate dehydrogenase activator BCH stimulating reductive amination prevents high fat/high fructose diet-induced steatohepatitis and hyperglycemia in C57BL/6J mice
Published in Scientific reports (22-11-2016)“…Individuals with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D) induced by high calorie western diet are characterized by enhanced…”
Get full text
Journal Article -
11
Atherosclerosis induced by a high-fat diet is alleviated by lithium chloride via reduction of VCAM expression in ApoE-deficient mice
Published in Vascular pharmacology (01-11-2010)“…Abstract Endothelial cell dysfunction may play an important role in the development of various vascular diseases, including atherosclerosis. Here we…”
Get full text
Journal Article -
12
Effect of sitagliptin plus metformin on β-cell function, islet integrity and islet gene expression in Zucker diabetic fatty rats
Published in Diabetes research and clinical practice (01-05-2011)“…Abstract Aim The combination of metformin and a dipeptidyl peptidase 4 (DPP-4) inhibitor has been shown to be an effective, safe, and well-tolerated treatment…”
Get full text
Journal Article -
13
Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes
Published in Molecular and cellular endocrinology (15-10-2011)“…► Elevated fatty acid levels have been thought to contribute to insulin resistance. ► GLUT4 gene repression may be a mediator for fatty acid-induced insulin…”
Get full text
Journal Article