Search Results - "Jung, Jee H."
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1
Atractylodin Ameliorates Colitis via PPARα Agonism
Published in International journal of molecular sciences (02-01-2023)“…Atractylodin is a major compound in the rhizome of Atractylodes lancea, an oriental herbal medicine used for the treatment of gastrointestinal diseases,…”
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2
Marine-Derived Penicillium Species as Producers of Cytotoxic Metabolites
Published in Marine drugs (24-10-2017)“…Since the discovery of penicillin, has become one of the most attractive fungal genera for the production of bioactive molecules. Marine-derived has provided…”
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3
Antimicrobial Compounds from Marine Invertebrates-Derived Microorganisms
Published in Current medicinal chemistry (01-08-2016)“…It is known that marine invertebrates, including sponges, tunicates, cnidaria or mollusks, host affluent and various communities of symbiotic microorganisms…”
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4
Design of balanced COX inhibitors based on anti-inflammatory and/or COX-2 inhibitory ascidian metabolites
Published in European journal of medicinal chemistry (15-10-2019)“…The aim of this study was to design and synthesize COX-1/COX-2 balanced inhibitors incorporating the structural motifs of anti-inflammatory ascidian…”
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5
Bioactive metabolites from the sponge-derived fungus Aspergillus versicolor
Published in Archives of pharmacal research (01-02-2010)“…As part of an ongoing search for bioactive metabolites from the fungus Aspergillus versicolor derived from a marine sponge Petrosia sp., an aromatic polyketide…”
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6
Evaluation of the inhibitory effects of eckol and dieckol isolated from edible brown alga Eisenia bicyclis on human monoamine oxidases A and B
Published in Archives of pharmacal research (01-04-2017)“…Eckol and dieckol are important phlorotannins found in edible brown algae including Eisenia bicyclis, Ecklonia stolonifera, and others. Inhibition of monoamine…”
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7
Discovery of urinary metabolomic biomarkers for early detection of acute kidney injury
Published in Molecular bioSystems (01-01-2016)“…The discovery of new biomarkers for early detection of drug-induced acute kidney injury (AKI) is clinically important. In this study, sensitive metabolomic…”
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8
A New Fungal Triterpene from the Fungus Aspergillus flavus Stimulates Glucose Uptake without Fat Accumulation
Published in Marine drugs (10-03-2022)“…Through activity-guided fractionation, a new triterpene (asperflagin, ) was isolated as a PPAR-γ agonist from the jellyfish-derived fungus . Asperflagin…”
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9
Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells
Published in International journal of oncology (01-09-2012)“…Sirtuins (SIRTs), NAD+-dependent class III histone deacetylases (HDACs), play an important role in the regulation of cell division, survival and senescence…”
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10
Neuroprotective Effect of Cyclo-(L-Pro-L-Phe) Isolated from the Jellyfish-Derived Fungus Aspergillus flavus
Published in Marine drugs (26-07-2021)“…Peroxisome proliferator-activated receptor (PPAR) expression has been implicated in pathological states such as cancer, inflammation, diabetes, and…”
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11
Nitric Oxide-Releasing Thermoresponsive Pluronic F127/Alginate Hydrogel for Enhanced Antibacterial Activity and Accelerated Healing of Infected Wounds
Published in Pharmaceutics (28-09-2020)“…Nitric oxide (NO), a highly reactive and lipophilic molecule, is one of the molecules present in the wound environment and implicated as an important regulator…”
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12
Viriditoxin Stabilizes Microtubule Polymers in SK-OV-3 Cells and Exhibits Antimitotic and Antimetastatic Potential
Published in Marine drugs (27-08-2020)“…Microtubules play a crucial role in mitosis and are attractive targets for cancer therapy. Recently, we isolated viriditoxin, a cytotoxic and antibacterial…”
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13
An Algal Metabolite-Based PPAR-γ Agonist Displayed Anti-Inflammatory Effect via Inhibition of the NF-κB Pathway
Published in Marine drugs (30-05-2019)“…In our previous study, a synthetic compound, (+)-( , )- , that incorporated the key structures of anti-inflammatory algal metabolites and the endogenous…”
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14
The In Vitro and In Vivo Anti-Inflammatory Effects of a Phthalimide PPAR-γ Agonist
Published in Marine drugs (04-01-2017)“…Previously, the authors found that 4-hydroxy-2-(4-hydroxyphenethyl) isoindoline-1,3-dione ( ) (a phthalimide analogue) bound to and activated peroxisome…”
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15
Advanced analytical method of nereistoxin using mixed-mode cationic exchange solid-phase extraction and GC/MS
Published in Forensic science international (01-07-2015)“…Highlights • A method for quantitation of NTX in human whole blood was developed. • The method was successfully applied to samples from cartap poisoning cases…”
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16
Kinetics and molecular docking studies of an anti-diabetic complication inhibitor fucosterol from edible brown algae Eisenia bicyclis and Ecklonia stolonifera
Published in Chemico-biological interactions (25-10-2013)“…[Display omitted] •Fucosterol exhibited mixed-type inhibition against RLAR and HRAR activities.•Fucosterol showed noncompetitive-type inhibition against PTP1B…”
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17
Dimeric Octaketide Spiroketals from the Jellyfish-Derived Fungus Paecilomyces variotii J08NF‑1
Published in Journal of natural products (Washington, D.C.) (25-11-2015)“…Paeciloketals (1–3), new benzannulated spiroketal derivatives, were isolated from the marine fungus Paecilomyces variotii derived from the giant jellyfish…”
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18
Cytotoxic cytochalasins from the endozoic fungus Phoma sp. of the giant jellyfish Nemopilema nomurai
Published in Bioorganic & medicinal chemistry letters (01-05-2012)“…Four new cytochalasin derivatives (1–4), together with cytochalasin B (5), were isolated from the fungus Phoma sp. obtained from the giant jellyfish Nemopilema…”
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A novel anthracene derivative, MHY412, induces apoptosis in doxorubicin-resistant MCF-7/Adr human breast cancer cells through cell cycle arrest and downregulation of P-glycoprotein expression
Published in International journal of oncology (01-01-2014)“…New potential chemotherapeutic strategies are required to overcome multidrug resistance (MDR) in cancer. This study investigated the anticancer effect of a…”
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20
Selective Cholinesterase Inhibitory Activities of a New Monoterpene Diglycoside and Other Constituents from Nelumbo nucifera Stamens
Published in Biological & Pharmaceutical Bulletin (2010)“…A new β-cyclogeraniol diglycoside (5), along with four known components, cycloartenol (1), p-hydroxybenzoic acid (2), vanilloloside (3), and…”
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