Search Results - "Jung, Hyun Ae"

High concordance of actionable genomic alterations identified between circulating tumor DNA–based and tissue‐based next‐generation sequencing testing in advanced non–small cell lung cancer: The Korean Lung Liquid Versus Invasive Biopsy Program by Park, Sehhoon, Olsen, Steve, Ku, Bo Mi, Lee, Min‐Sang, Jung, Hyun‐Ae, Sun, Jong‐Mu, Lee, Se‐Hoon, Ahn, Jin Seok, Park, Keunchil, Choi, Yoon‐La, Ahn, Myung‐Ju

“…Background Because of the growing number of actionable biomarkers in non–small cell lung cancer (NSCLC), sufficient tissue availability for testing is becoming…”
Get full text

Immune checkpoint inhibitor use and the incidence of hepatitis B virus reactivation or immune‐related hepatitis in non–small cell lung cancer patients with chronic hepatitis B by Hong, Joohyun, Lee, Jiyun, Park, Sehhoon, Jung, Hyun‐Ae, Sun, Jong‐Mu, Lee, Se‐Hoon, Ahn, Jin Seok, Sinn, Dong Hyun, Ahn, Myung‐Ju

“…Background The safety of immune‐checkpoint inhibitors (ICIs) has not been thoroughly investigated in non–small cell lung cancer (NSCLC) patients with chronic…”
Get full text

Longitudinal monitoring by next‐generation sequencing of plasma cell‐free DNA in ALK rearranged NSCLC patients treated with ALK tyrosine kinase inhibitors by Kwon, Minsuk, Ku, Bo mi, Olsen, Steve, Park, Sehhoon, Lefterova, Martina, Odegaard, Justin, Jung, Hyun‐Ae, Sun, Jong‐Mu, Lee, Se‐Hoon, Ahn, Jin Seok, Park, Keunchil, Ahn, Myung‐Ju

“…Background Patients with ALK‐rearranged non‐small cell lung cancer (ALK+ NSCLC) inevitably acquire resistance to ALK inhibitors. Longitudinal monitoring of…”
Get full text

Prognostic Value of the Neutrophil-to-Lymphocyte Ratio before and after Radiotherapy for Anaplastic Thyroid Carcinoma by Park, Jiyun, Park, Jun, Shin, Jung-Hee, Oh, Young-Lyun, Jung, Hyun-Ae, Chung, Man-Ki, Choe, Jun-Ho, Ahn, Yong-Chan, Kim, Sun-Wook, Chung, Jae-Hoon, Kim, Tae-Hyuk, Noh, Jae-Myoung

“…The neutrophil-lymphocyte ratio (NLR) is a marker of systemic inflammation, and its elevation has recently been associated with poor survival in many solid…”
Get full text

Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma by Kim, Nayoung, Kim, Hong Kwan, Lee, Kyungjong, Hong, Yourae, Cho, Jong Ho, Choi, Jung Won, Lee, Jung-Il, Suh, Yeon-Lim, Ku, Bo Mi, Eum, Hye Hyeon, Choi, Soyean, Choi, Yoon-La, Joung, Je-Gun, Park, Woong-Yang, Jung, Hyun Ae, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Park, Keunchil, Ahn, Myung-Ju, Lee, Hae-Ock

“…Advanced metastatic cancer poses utmost clinical challenges and may present molecular and cellular features distinct from an early-stage cancer. Herein, we…”
Get full text

Real world data of durvalumab consolidation after chemoradiotherapy in stage III non-small-cell lung cancer by Jung, Hyun Ae, Noh, Jae Myoung, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Ahn, Myung-Ju, Pyo, Hongryull, Ahn, Yong Chan, Park, Keunchil

“…•Real world data showed 55.3 % of patients did not meet the criteria of the PACIFIC study.•The incidence of grade 3 radiation pneumonitis was 18.2 % in…”
Get full text

Artificial Intelligence-Powered Spatial Analysis of Tumor-Infiltrating Lymphocytes as Complementary Biomarker for Immune Checkpoint Inhibition in Non-Small-Cell Lung Cancer by Park, Sehhoon, Ock, Chan-Young, Kim, Hyojin, Pereira, Sergio, Park, Seonwook, Ma, Minuk, Choi, Sangjoon, Kim, Seokhwi, Shin, Seunghwan, Aum, Brian Jaehong, Paeng, Kyunghyun, Yoo, Donggeun, Cha, Hongui, Park, Sunyoung, Suh, Koung Jin, Jung, Hyun Ae, Kim, Se Hyun, Kim, Yu Jung, Sun, Jong-Mu, Chung, Jin-Haeng, Ahn, Jin Seok, Ahn, Myung-Ju, Lee, Jong Seok, Park, Keunchil, Song, Sang Yong, Bang, Yung-Jue, Choi, Yoon-La, Mok, Tony S, Lee, Se-Hoon

“…Biomarkers on the basis of tumor-infiltrating lymphocytes (TIL) are potentially valuable in predicting the effectiveness of immune checkpoint inhibitors (ICI)…”
Get full text

Phase III, Randomized Study of Atezolizumab Plus Bevacizumab and Chemotherapy in Patients With EGFR - or ALK -Mutated Non-Small-Cell Lung Cancer (ATTLAS, KCSG-LU19-04) by Park, Sehhoon, Kim, Tae Min, Han, Ji-Youn, Lee, Gyeong-Won, Shim, Byoung Yong, Lee, Yun-Gyoo, Kim, Sang-We, Kim, Il Hwan, Lee, Suee, Kim, Yu Jung, Park, Ji Hyun, Park, Sang-Gon, Lee, Ki Hyeong, Kang, Eun Joo, Kim, Ju Won, Shin, Seong-Hoon, Ock, Chan-Young, Nam, Byung-Ho, Lee, Jaebong, Jung, Hyun-Ae, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Ahn, Myung-Ju

“…In the treatment of non-small-cell lung cancer (NSCLC) with a driver mutation, the role of anti-PD-(L)1 antibody after tyrosine kinase inhibitor (TKI) remains…”
Get full text

Immune Checkpoint Inhibitors for Non-Small-Cell Lung Cancer with Brain Metastasis : The Role of Gamma Knife Radiosurgery by Lee, Min Ho, Cho, Kyung-Rae, Choi, Jung Won, Kong, Doo-Sik, Seol, Ho Jun, Nam, Do-Hyun, Jung, Hyun Ae, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Ahn, Myung-Ju, Park, Keunchil, Lee, Jung-Il

“…Objective : Immune checkpoint inhibitors (ICIs) are approved for treating non-small-cell lung cancer (NSCLC); however, the safety and efficacy of combined ICI…”
Get full text

Comparative effectiveness of lazertinib in patients with EGFR T790M-positive non-small-cell lung cancer using a real-world external control by Jeon, Ha-Lim, Kwak, Meesong, Kim, Sohee, Yu, Hye-Yeon, Shin, Ju-Young, Jung, Hyun Ae

“…Lazertinib is a recently developed third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors used for patients with advanced EGFR…”
Get full text

Outstanding clinical efficacy of PD-1/PD-L1 inhibitors for pulmonary pleomorphic carcinoma by Lee, Jiyun, Choi, Yoon La, Jung, Hyun Ae, Lee, Se-Hoon, Ahn, Jin Seok, Ahn, Myung-Ju, Park, Keunchil, Sun, Jong-Mu

“…We evaluated programmed death ligand 1 (PD-L1) expression and efficacy of PD-1/PD-L1 inhibitors in patients with pulmonary pleomorphic carcinoma (PC). We…”
Get full text

Association of T Cell Senescence with Radiation Pneumonitis in Patients with Non-small Cell Lung Cancer by Kim, Kyung Hwan, Pyo, Hongryull, Lee, Hoyoung, Oh, Dongryul, Noh, Jae Myoung, Ahn, Yong Chan, Kim, Chang Gon, Yoon, Hong In, Lee, Jiyun, Park, Sehhoon, Jung, Hyun-Ae, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Park, Keunchil, Ku, Bo mi, Shin, Eui-Cheol, Ahn, Myung-Ju

“…Associations between immunosenescence and radiation pneumonitis (RP) are largely unknown. We aimed to identify a peripheral blood T cell senescence biomarker…”
Get full text

Prognostic value of FOXP3+ regulatory T cells for patients with locally advanced oropharyngeal squamous cell carcinoma by Joon Young Hur, Bo Mi Ku, Sehhoon Park, Hyun Ae Jung, Se-Hoon Lee, Myung-Ju Ahn

“…BackgroundOropharyngeal squamous cell carcinoma (OPSCC) is the most common neoplasm originating at the base of the tongue or in the tonsils or soft palate. In…”
Get full text

Prognostic value of FOXP3+ regulatory T cells for patients with locally advanced oropharyngeal squamous cell carcinoma by Hur, Joon Young, Ku, Bo Mi, Park, Sehhoon, Jung, Hyun Ae, Lee, Se-Hoon, Ahn, Myung-Ju

“…Background Oropharyngeal squamous cell carcinoma (OPSCC) is the most common neoplasm originating at the base of the tongue or in the tonsils or soft palate. In…”
Get full text

Dynamics of Circulating Immune Cells During Chemoradiotherapy in Patients with Non-Small Cell Lung Cancer Support Earlier Administration of Anti-PD-1/PD-L1 Therapy by Kim, Kyung Hwan, Pyo, Hongryull, Lee, Hoyoung, Oh, Dongryul, Noh, Jae Myoung, Ahn, Yong Chan, Yoon, Hong In, Moon, Hyowon, Lee, Jiyun, Park, Sehhoon, Jung, Hyun-Ae, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Park, Keunchil, Ku, Bo Mi, Ahn, Myung-Ju, Shin, Eui-Cheol

“…Chemoradiotherapy (CRT) followed by consolidation immune checkpoint inhibitors significantly improves survival in unresectable locally advanced non-small cell…”
Get full text

Programmed Death-Ligand 1 Copy Number Alteration as an Adjunct Biomarker of Response to Immunotherapy in Advanced NSCLC by Hong, Tae Hee, Bang, Yeong Hak, Joe, Cheol Yong, Hwang, Soohyun, Lee, Boram, Lee, Naeun, Park, Sehhoon, Jung, Hyun-Ae, Sun, Jong-Mu, Ahn, Jin Seok, Ahn, Myung-Ju, Choi, Yoon-La, Lee, Se-Hoon

“…This study aimed to evaluate the value of programmed death-ligand 1 (PD-L1) copy number (CN) alteration as an additional biomarker to standard…”
Get more information

Clinical outcomes of immune checkpoint inhibitors for patients with recurrent or metastatic head and neck cancer: real-world data in Korea by Kim, Hyera, Kwon, Minsuk, Kim, Binnari, Jung, Hyun Ae, Sun, Jong-Mu, Lee, Se-Hoon, Park, Keunchil, Ahn, Myung-Ju

“…Anti-PD1 inhibitors have been approved for the treatment of recurrent or metastatic head and neck cancer (HNC), as a result of Global Phase III trials…”
Get full text

Mutations in genes affecting DNA methylation enhances responses to decitabine in patients with myelodysplastic syndrome by Jung, Hyun Ae, Jung, Chul Won, Jang, Jun Ho

“…In this study, we tested whether mutations in the methylation pathway genes ten-eleven-translocation 2 (TET2) and DNA methyltransferase gene 3A (DNMT3A)…”
Get full text

Clinical utility of circulating tumor DNA profiling in detecting targetable fusions in non-small cell lung cancer by Kim, Young-gon, Lee, Boram, Ha, Changhee, Lee, Cheonghwa, Jung, Hyun Ae, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Myung-Ju, Choi, Yoon-La, Park, Sehhoon, Kim, Jong-Won

“…Introduction Numerous studies have suggested high concordance between tissue and circulating tumor DNA (ctDNA) comprehensive genomic profiling (CGP) tests but…”
Get full text

Unveiling the influence of tumor and immune signatures on immune checkpoint therapy in advanced lung cancer by Kim, Nayoung, Park, Sehhoon, Jo, Areum, Eum, Hye Hyeon, Kim, Hong Kwan, Lee, Kyungjong, Cho, Jong Ho, Ku, Bo Mi, Jung, Hyun Ae, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Lee, Jung-Il, Choi, Jung Won, Jeong, Dasom, Kang, Huiram, Kim, Jeong Yeon, Choi, Jung Kyoon, Lee, Hae-Ock, Ahn, Myung-Ju

“…This study investigates the variability among patients with non-small cell lung cancer (NSCLC) in their responses to immune checkpoint inhibitors (ICIs)…”
Get full text