Search Results - "Jung, Hyein"
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Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics
Published in Experimental & molecular medicine (01-10-2023)“…Several studies have utilized a lipid nanoparticle delivery system to enhance the effectiveness of mRNA therapeutics and vaccines. However, these nanoparticles…”
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2
PRID: Prediction Model Using RWR for Interactions between Drugs
Published in Pharmaceutics (01-10-2023)“…Drug–drug interactions (DDI) occur because of the unexpected pharmacological effects of drug pairs. Although drug efficacy can be improved by taking two or…”
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3
Real-Time UV/VIS Spectroscopy to Observe Photocatalytic Degradation
Published in Catalysts (01-04-2023)“…In this work, we have developed a real-time UV/VIS spectroscopy method using a broadband Xenon Arc lamp to detect photocatalytic reactions in real time. A CMOS…”
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Association between kimchi consumption and obesity based on BMI and abdominal obesity in Korean adults: a cross-sectional analysis of the Health Examinees study
Published in BMJ open (30-01-2024)“…ObjectivePrevious animal studies have shown the anti-obesity effect of kimchi-derived probiotic lactic acid bacteria. However, only a few epidemiological…”
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Association of hypertension with noodle consumption among Korean adults based on the Health Examinees(HEXA) study
Published in Nutrition research and practice (01-04-2024)“…The prevalence of hypertension is increasing, and noodles have a high sodium content, so noodle consumption might be associated with a higher prevalence of…”
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Relationship between age at menarche and metabolic diseases in Korean postmenopausal women: The Korea National Health and Nutrition Examination Survey 2016-2018
Published in PloS one (25-01-2023)“…Cardiovascular disease is the leading cause of morbidity and mortality in postmenopausal women. Early menarche may be associated with an increased risk of…”
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Non-alcoholic fatty liver disease is associated with hyperandrogenism in women with polycystic ovary syndrome
Published in Scientific reports (17-08-2023)“…Polycystic ovary syndrome (PCOS) is a highly complex reproductive metabolic disorder and women with PCOS have high prevalence of non-alcoholic fatty liver…”
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Effectiveness of oral phloroglucinol as a premedication for unsedated esophagogastroduodenoscopy: A prospective, double-blinded, placebo-controlled, randomized trial
Published in PloS one (04-08-2021)“…Background Anti-spasmodic agents are commonly injected during esophagogastroduodenoscopy (EGD) to improve visualization of the gastric mucosa by inhibiting…”
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Development of Lipid Nanoparticle Formulation for the Repeated Administration of mRNA Therapeutics
Published in Biomaterials research (2024)“…During the COVID-19 pandemic, mRNA vaccines emerged as a rapid and effective solution for global immunization. The success of COVID-19 mRNA vaccines has…”
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10
Investigation of heteroscedasticity in polygenic risk scores across 15 quantitative traits
Published in Frontiers in genetics (09-05-2023)“…The polygenic risk score (PRS) could be used to stratify individuals with high risk of diseases and predict complex trait of individual in a population…”
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Identification of asthma-related genes using asthmatic blood eQTLs of Korean patients
Published in BMC medical genomics (24-10-2023)“…Abstract Background More than 200 asthma-associated genetic variants have been identified in genome-wide association studies (GWASs). Expression quantitative…”
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12
Novel piperazine-based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety
Published in Bioengineering & translational medicine (01-11-2023)“…mRNA-based protein replacement therapy has received much attention as a novel intervention in clinical disease treatment. Lipid nanoparticles (LNPs) are widely…”
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13
Integration of risk factor polygenic risk score with disease polygenic risk score for disease prediction
Published in Communications biology (13-02-2024)“…Polygenic risk score (PRS) is useful for capturing an individual’s genetic susceptibility. However, previous studies have not fully exploited the potential of…”
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14
The association between fruit and vegetable consumption and metabolic syndrome in Korean adults: does multivitamin use matter?
Published in Epidemiology and health (19-04-2022)“…OBJECTIVES: Metabolic syndrome (MetS) is closely associated with dietary intake; however, few studies have investigated whether the consumption of fruits and…”
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Associations of GNAS Mutations with Surgical Outcomes in Patients with Growth Hormone-Secreting Pituitary Adenoma
Published in Endocrinology and metabolism (Seoul) (01-04-2021)“…The guanine nucleotide-binding protein, alpha stimulating (GNAS) gene has been associated with growth hormone (GH)-secreting pituitary adenoma. We investigated…”
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Association between Tomato and Lycopene Consumption and Risk of All‐Cause and Cause‐Specific Mortality: Korean Genome and Epidemiology Study Cohort
Published in Molecular nutrition & food research (01-02-2023)“…Scope Tomato has well‐known beneficial health effects and is an important source of lycopene. The study aims to clarify the evidence for the association…”
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Lipid nanoparticles (LNPs) for in vivo RNA delivery and their breakthrough technology for future applications
Published in Advanced drug delivery reviews (01-09-2023)“…RNA therapeutics show a significant breakthrough for the treatment of incurable diseases and genetic disorders by regulating disease-related gene expression…”
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Two-stage dynamic real-time optimization framework using parameter-dependent differential dynamic programming
Published in Computers & chemical engineering (01-01-2025)“…The purpose of chemical process control includes proactive adjustment of the operation to make the most profit out of it. Within this context, real-time…”
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Association of milk consumption with management and incidence of hypertension among South Korean adults: A prospective analysis of the health examinees study cohort
Published in Nutrition, metabolism, and cardiovascular diseases (01-11-2022)“…Studies have revealed a positive relationship between milk consumption and hypertension. However, few researchers have investigated the association between…”
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Status of dyslipidemia management and statin undertreatment in Korean cancer survivors: A Korean National Health and Nutrition Examination Survey study
Published in European journal of preventive cardiology (23-07-2021)“…Due to improving cancer treatment results, non-cancer mortality is an important issue for cancer survivors. Cardiovascular diseases are the leading causes of…”
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