Search Results - "Jung, Heiyoun"

Regulation of Ligands for the NKG2D Activating Receptor by Raulet, David H, Gasser, Stephan, Gowen, Benjamin G, Deng, Weiwen, Jung, Heiyoun

“…NKG2D is an activating receptor expressed by all NK cells and subsets of T cells. It serves as a major recognition receptor for detection and elimination of…”
Get full text

RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry by Jung, Heiyoun, Hsiung, Benjamin, Pestal, Kathleen, Procyk, Emily, Raulet, David H

“…The NKG2D stimulatory receptor expressed by natural killer cells and T cell subsets recognizes cell surface ligands that are induced on transformed and…”
Get full text

Inappropriate p53 activation during development induces features of CHARGE syndrome by Van Nostrand, Jeanine L., Brady, Colleen A., Jung, Heiyoun, Fuentes, Daniel R., Kozak, Margaret M., Johnson, Thomas M., Lin, Chieh-Yu, Lin, Chien-Jung, Swiderski, Donald L., Vogel, Hannes, Bernstein, Jonathan A., Attié-Bitach, Tania, Chang, Ching-Pin, Wysocka, Joanna, Martin, Donna M., Attardi, Laura D.

“…Inappropriate activation of the tumour-suppressor protein p53 during development can promote phenotypes similar to those of CHARGE syndrome, suggesting that…”
Get full text

Expression of the RAE-1 family of stimulatory NK-cell ligands requires activation of the PI3K pathway during viral infection and transformation by Tokuyama, Maria, Lorin, Clarisse, Delebecque, Frederic, Jung, Heiyoun, Raulet, David H, Coscoy, Laurent

“…Natural killer (NK) cells are lymphocytes that play a major role in the elimination of virally-infected cells and tumor cells. NK cells recognize and target…”
Get full text

Abstract A90: Combination therapy of chemokine receptor inhibition plus PDL-1 blockade potentiates anti-tumor effects in a murine model of breast cancer by Jung, Heiyoun

“…Abstract Trafficking and expansion of myeloid derived suppressor cells (MDSCs) plays a major role in immune suppression of tumor. MDSCs express chemokine…”
Get full text

Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage by Younger, Scott T, Kenzelmann-Broz, Daniela, Jung, Heiyoun, Attardi, Laura D, Rinn, John L

“…The tumor suppressor p53 has been studied extensively as a direct transcriptional activator of protein-coding genes. Recent studies, however, have shed light…”
Get full text

Expression of ligands for the NKG2D activating receptor are linked to proliferative signals (108.2) by Jung, Heiyoun, Raulet, David

“…Abstract NKG2D is an activating receptor expressed on NK cells, CD8 T cells, and portions of NKT cells, gd T cells and CD4 T cells. The ligands for NKG2D…”
Get full text

Abstract 564: Combination therapy of chemokine receptor inhibition plus PD-L1 blockade potentiates antitumor effects in a murine model of breast cancer by Jung, Heiyoun, Ertl, Linda, Ebsworth, Karen, Janson, Christine, Zhang, Penglie, Sreenivas, Punna, Schall, Thomas, Charo, Israel

“…Abstract Trafficking and expansion of myeloid derived suppressor cells (MDSCs) plays a major role in the immune suppression of tumors. MDSCs express chemokine…”
Get full text

Abstract 5655: Inhibition of CCR2 potentiates checkpoint inhibitor immunotherapy in murine model of pancreatic cancer by Janson, Christine, Jung, Heiyoun, Ertl, Linda, Liu, Shirley, Dang, Ton, Zeng, Yibin, Krasinski, Antoni, McMahon, Jeff, Zhang, Penglie, Charo, Israel, Singh, Rajinder, Schall, Thomas J.

“…Abstract Pancreatic cancer is an aggressive malignancy with a 5 year survival rate of less than five percent. The predominant immune cells infiltrating the…”
Get full text

The inhibition of CCR2 to modify the microenvironment in pancreatic cancer mouse model and to support the profiling of the CCR2 inhibitor CCX872-B in patients by Wang-Gillam, Andrea, Noel, Marcus Smith, Sleijfer, Stefan, Jung, Heiyoun, Lohr, Lisa, Zhao, Niky, Miao, Shichang, Potarca, Antonia, Charo, Israel, Bekker, Petrus, Schall, Thomas J.

“…Abstract only…”
Get full text

Combination therapy of chemokine receptor inhibition plus PDL-1 blockade potentiates anti-tumor effects in a murine model of breast cancer by Jung, Heiyoun, Bischof, Ashley, Ebsworth, Karen, Ertl, Linda, Schall, Thomas, Charo, Israel

“…Trafficking and expansion of myeloid derived suppressor cells (MDSCs) plays a major role in immune suppression of tumor. MDSCs express chemokine receptors…”
Get full text

Expression of Ligands for the NKG2D Activating Receptor are Linked to Proliferative Signals by Jung, Heiyoun

“…NKG2D is a stimulatory receptor expressed by natural killer cells and subsets of T cells. The receptor recognizes a set of self-encoded cell surface proteins…”
Get full text