Search Results - "Jung, David H."

Impact of COVID-19 on Presentation of Sudden Sensorineural Hearing Loss at a Single Institution by Chari, Divya A., Parikh, Ayush, Kozin, Elliott D., Reed, Meaghan, Jung, David H.

“…The coronavirus disease 2019 (COVID-19) pandemic resulted in widespread unprecedented changes to the health care system. Herein, we sought to assess the impact…”
Get full text

Evidence of cochlear neural degeneration in normal-hearing subjects with tinnitus by Vasilkov, Viacheslav, Caswell-Midwinter, Benjamin, Zhao, Yan, de Gruttola, Victor, Jung, David H., Liberman, M. Charles, Maison, Stéphane F.

“…Tinnitus, reduced sound-level tolerance, and difficulties hearing in noisy environments are the most common complaints associated with sensorineural hearing…”
Get full text

Otogenic brain abscesses: A systematic review by Duarte, Maria J., Kozin, Elliott D., Barshak, Miriam B., Reinshagen, Katherine, Knoll, Renata M., Abdullah, Kalil G., Welling, D. Bradley, Jung, David H.

“…Objective Otogenic brain abscesses are one of the most significant life‐threatening complications of otologic infections. Given their low prevalence, otogenic…”
Get full text

Clinical trials for inner ear drugs: Design and execution challenges by Jung, David H., Rauch, Steven D.

“…The development of therapies for the inner ear presents unique opportunities and challenges. On the one hand, the ear presents an opportunity for localized…”
Get full text

A Novel Small Molecule Neurotrophin-3 Analogue Promotes Inner Ear Neurite Outgrowth and Synaptogenesis In vitro by Kempfle, Judith S., Duro, Marlon V., Zhang, Andrea, Amador, Carolina D., Kuang, Richard, Lu, Ryan, Kashemirov, Boris A., Edge, Albert S., McKenna, Charles E., Jung, David H.

“…Sensorineural hearing loss is irreversible and is associated with the loss of spiral ganglion neurons (SGNs) and sensory hair cells within the inner ear…”
Get full text

Training Surgeon Scholars: Grant Writing Workshops During Residency by Chen, Jenny X., Gray, Stacey T., Jung, David H.

“…Surgical residents may have limited experience with grant writing even though it is an important skill for academic physicians. We describe a novel curriculum…”
Get full text

Development and validation of a rabbit model of Pseudomonas aeruginosa non-ventilated pneumonia for preclinical drug development by Gras, Emmanuelle, Vu, Trang T T, Nguyen, Nhu T Q, Tran, Vuvi G, Mao, Yanjie, Tran, Nguyen D, Mai, Nam H, Dong, Oliver X, Jung, David H, Iorio, Natalia L P P, Povoa, Helvecio C C, Pinheiro, Marcos Gabriel, Aguiar-Alves, Fabio, Weiss, William J, Zheng, Bo, Cheng, Lily I, Stover, Charles K, Sellman, Bret R, DiGiandomenico, Antonio, Gibault, Laure, Valour, Florent, Diep, Binh An

“…New drugs targeting antimicrobial resistant pathogens, including , have been challenging to evaluate in clinical trials, particularly for the non-ventilated…”
Get full text

Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2 by Prabhakar, Shilpa, Beauchamp, Roberta L., Cheah, Pike See, Yoshinaga, Akiko, Haidar, Edwina Abou, Lule, Sevda, Mani, Gayathri, Maalouf, Katia, Stemmer-Rachamimov, Anat, Jung, David H., Welling, D. Bradley, Giovannini, Marco, Plotkin, Scott R., Maguire, Casey A., Ramesh, Vijaya, Breakefield, Xandra O.

“…Loss of function of the neurofibromatosis type 2 (NF2) tumor suppressor gene leads to the formation of schwannomas, meningiomas, and ependymomas, comprising…”
Get full text

Topical fibroblast growth factor‐2 for treatment of chronic tympanic membrane perforations by Santos, Felipe, Shu, Edina, Lee, Daniel J., Jung, David H., Quesnel, Alicia M., Stankovic, Konstantina M., Abdul‐Aziz, Dunia E., Bay, Camden P., Quinkert, Amy, Welling, D. Bradley

“…Objective To determine the efficacy of fibroblast growth factor‐2 (FGF‐2) in treating chronic nonhealing tympanic membrane (TM) perforations. Method…”
Get full text

Improvement in word recognition following treatment failure for sudden sensorineural hearing loss by Jan, Taha A., Kozin, Elliott D., Kanumuri, Vivek V., Sethi, Rosh K., Jung, David H.

“…Objectives Patients with sudden sensorineural hearing loss (SSNHL) may have word recognition scores (WRS) that correlate with pure tone average (PTA). We…”
Get full text

Demonstration and Mitigation of Aerosol and Particle Dispersion During Mastoidectomy Relevant to the COVID-19 Era by Chen, Jenny X., Workman, Alan D., Chari, Divya A., Jung, David H., Kozin, Elliott D., Lee, Daniel J., Welling, D. Bradley, Bleier, Benjamin S., Quesnel, Alicia M.

“…BACKGROUND:COVID-19 has become a global pandemic with a dramatic impact on healthcare systems. Concern for viral transmission necessitates the investigation of…”
Get full text

Demonstration and Mitigation of Aerosol and Particle Dispersion During Mastoidectomy Relevant to the COVID-19 Era by Chen, Jenny X, Workman, Alan D, Chari, Divya A, Jung, David H, Kozin, Elliott D, Lee, Daniel J, Welling, D Bradley, Bleier, Benjamin S, Quesnel, Alicia M

“…COVID-19 has become a global pandemic with a dramatic impact on healthcare systems. Concern for viral transmission necessitates the investigation of otologic…”
Get full text

Aerosol Dispersion During Mastoidectomy and Custom Mitigation Strategies for Otologic Surgery in the COVID-19 Era by Chari, Divya A., Workman, Alan D., Chen, Jenny X., Jung, David H., Abdul-Aziz, Dunia, Kozin, Elliott D., Remenschneider, Aaron K., Lee, Daniel J., Welling, D. Bradley, Bleier, Benjamin S., Quesnel, Alicia M.

“…Objective To investigate small-particle aerosolization from mastoidectomy relevant to potential viral transmission and to test source-control mitigation…”
Get full text

Prevention and management of hearing loss in patients receiving ototoxic medications by Lindeborg, Michael, Jung, David, Chan, Dylan, Mitnick, Carole

“…Sous l'impulsion des défenseurs des droits des patients, l'Organisation mondiale de la Santé a publié une version actualisée des lignes directrices relatives a…”
Get full text

Radiologically-proven New Development of Superior Semicircular Canal Dehiscence Associated With Development of Superior Semicircular Canal Dehiscence Syndrome by Chari, Divya A., Juliano, Amy F., Jung, David H.

“…OBJECTIVE:This report describes a case of development of radiologic superior semicircular canal dehiscence and reviews the literature for pertinent clinical…”
Get full text

Protective Efficacy of Monoclonal Antibodies Neutralizing Alpha-Hemolysin and Bicomponent Leukocidins in a Rabbit Model of Staphylococcus aureus Necrotizing Pneumonia by Vu, Trang T T, Nguyen, Nhu T Q, Tran, Vuvi G, Gras, Emmanuelle, Mao, Yanjie, Jung, David H, Tkaczyk, Christine, Sellman, Bret R, Diep, Binh An

“…is a major human pathogen that causes a wide range of infections by producing an arsenal of cytotoxins. We found that passive immunization with either a…”
Get full text

Patient‐reported auditory handicap measures following mild traumatic brain injury by Knoll, Renata M., Herman, Seth D., Lubner, Rory J., Babu, Ashwin N., Wong, Kevin, Sethi, Rosh K. V., Chen, Jenny X., Rauch, Steven D., Remenschneider, Aaron K., Jung, David H., Kozin, Elliott D.

“…Objectives/Hypothesis Few studies have specifically addressed auditory complaints in patients with nonblast mild traumatic brain injury (mTBI). Herein, we…”
Get full text

Intracochlear New Fibro-Ossification and Neuronal Degeneration Following Cochlear Implant Electrode Translocation: Long-Term Histopathological Findings in Humans by Knoll, Renata M., Trakimas, Danielle R., Wu, Matthew J., Lubner, Rory J., Nadol, Joseph B., Ishiyama, Akira, Santos, Felipe, Jung, David H., Remenschneider, Aaron K., Kozin, Elliott D.

“…We aim to assess the histopathology of human temporal bones (TBs) with evidence of cochlear implantation (CI) electrode scalar translocation. Otopathology…”
Get full text

Voluntary Field Recall of Advanced Bionics HiRes Cochlear Implants: A Single-Institution Experience by McHugh, Christopher I., Swedenborg, Britta K., Chen, Jenny X., Jung, David H., Mankarious, Leila A., Quesnel, Alicia M., Cohen, Michael S., Arenberg, Julie G., Franck, Kevin H., Santos, Felipe

“…In 2020, Advanced Bionics (AB) announced a recall of two cochlear implant (CI) models, the "HiRes Ultra" and "HiRes Ultra 3D", because of reports of hearing…”
Get full text

Recent advances in therapeutics and drug delivery for the treatment of inner ear diseases: a patent review (2011-2015) by Nguyen, Kim, Kempfle, Judith S, Jung, David H, McKenna, Charles E

“…Inner ear disorders such as hearing loss, tinnitus, and Ménière's disease significantly impact the quality of life of affected individuals. Treatment of such…”
Get more information