Search Results - "Jung, Christian B"

Dantrolene rescues arrhythmogenic RYR2 defect in a patient‐specific stem cell model of catecholaminergic polymorphic ventricular tachycardia by Jung, Christian B., Moretti, Alessandra, Mederos y Schnitzler, Michael, Iop, Laura, Storch, Ursula, Bellin, Milena, Dorn, Tatjana, Ruppenthal, Sandra, Pfeiffer, Sarah, Goedel, Alexander, Dirschinger, Ralf J., Seyfarth, Melchior, Lam, Jason T., Sinnecker, Daniel, Gudermann, Thomas, Lipp, Peter, Laugwitz, Karl‐Ludwig

“…Coordinated release of calcium (Ca 2+ ) from the sarcoplasmic reticulum (SR) through cardiac ryanodine receptor (RYR2) channels is essential for cardiomyocyte…”
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Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors by Molatore, Sara, Kiermaier, Eva, Jung, Christian B, Lee, Misu, Pulz, Elke, Höfler, Heinz, Atkinson, Michael J, Pellegata, Natalia S

“…p27Kip1 (p27) is an important negative regulator of the cell cycle and a putative tumor suppressor. The finding that a spontaneous germline frameshift mutation…”
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Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome by Bellin, Milena, Casini, Simona, Davis, Richard P, D'Aniello, Cristina, Haas, Jessica, Ward-van Oostwaard, Dorien, Tertoolen, Leon G J, Jung, Christian B, Elliott, David A, Welling, Andrea, Laugwitz, Karl-Ludwig, Moretti, Alessandra, Mummery, Christine L

“…Patient‐specific induced pluripotent stem cells (iPSCs) will assist research on genetic cardiac maladies if the disease phenotype is recapitulated in vitro …”
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Mouse and human induced pluripotent stem cells as a source for multipotent Isl1⁺ cardiovascular progenitors by Moretti, Alessandra, Bellin, Milena, Jung, Christian B, Thies, Tu-Mai, Takashima, Yasuhiro, Bernshausen, Alexandra, Schiemann, Matthias, Fischer, Stefanie, Moosmang, Sven, Smith, Austin G, Lam, Jason T, Laugwitz, Karl-Ludwig

“…Ectopic expression of defined sets of genetic factors can reprogram somatic cells to create induced pluripotent stem (iPS) cells. The capacity to direct human…”
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Neuropotent self-renewing neural stem (NS) cells derived from mouse induced pluripotent stem (iPS) cells by Onorati, Marco, Camnasio, Stefano, Binetti, Maurizio, Jung, Christian B., Moretti, Alessandra, Cattaneo, Elena

“…Neural stem (NS) cells are a homogenous population of stem cells that expands in monolayer under serum-free conditions while remaining highly neuropotent…”
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Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome: Isogenic pairs of LQT2 pluripotent stem cells by Bellin, Milena, Casini, Simona, Davis, Richard P, D'Aniello, Cristina, Haas, Jessica, Ward-van Oostwaard, Dorien, Tertoolen, Leon G J, Jung, Christian B, Elliott, David A, Welling, Andrea, Laugwitz, Karl-Ludwig, Moretti, Alessandra, Mummery, Christine L

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