Search Results - "Junbo Hu"

IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation by Hu, Fuqing, Song, Da, Yan, Yumeng, Huang, Changsheng, Shen, Chentao, Lan, Jingqin, Chen, Yaqi, Liu, Anyi, Wu, Qi, Sun, Li, Xu, Feng, Hu, Fayong, Chen, Lisheng, Luo, Xuelai, Feng, Yongdong, Huang, Shengyou, Hu, Junbo, Wang, Guihua

“…Extracellular cytokines are enriched in the tumor microenvironment and regulate various important properties of cancers, including autophagy. However, the…”
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Robust whole slide image analysis for cervical cancer screening using deep learning by Cheng, Shenghua, Liu, Sibo, Yu, Jingya, Rao, Gong, Xiao, Yuwei, Han, Wei, Zhu, Wenjie, Lv, Xiaohua, Li, Ning, Cai, Jing, Wang, Zehua, Feng, Xi, Yang, Fei, Geng, Xiebo, Ma, Jiabo, Li, Xu, Wei, Ziquan, Zhang, Xueying, Quan, Tingwei, Zeng, Shaoqun, Chen, Li, Hu, Junbo, Liu, Xiuli

“…Computer-assisted diagnosis is key for scaling up cervical cancer screening. However, current recognition algorithms perform poorly on whole slide image (WSI)…”
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M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer by Lan, Jingqin, Sun, Li, Xu, Feng, Liu, Lu, Hu, Fuqing, Song, Da, Hou, Zhenlin, Wu, Wei, Luo, Xuelai, Wang, Jing, Yuan, Xianglin, Hu, Junbo, Wang, Guihua

“…: Clinical and experimental evidence has shown that tumor-associated macrophages promote cancer initiation and progression. However, the macrophage-derived…”
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Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS by Zhang, Weina, Wang, Guihua, Xu, Zhi-Gang, Tu, Haiqing, Hu, Fuqing, Dai, Jiang, Chang, Yan, Chen, Yaqi, Lu, Yanjun, Zeng, Haolong, Cai, Zhen, Han, Fei, Xu, Chuan, Jin, Guoxiang, Sun, Li, Pan, Bo-Syong, Lai, Shiue-Wei, Hsu, Che-Chia, Xu, Jia, Chen, Zhong-Zhu, Li, Hong-Yu, Seth, Pankaj, Hu, Junbo, Zhang, Xuemin, Li, Huiyan, Lin, Hui-Kuan

“…RLR-mediated type I IFN production plays a pivotal role in elevating host immunity for viral clearance and cancer immune surveillance. Here, we report that…”
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The Pathogenesis of Nonalcoholic Fatty Liver Disease: Interplay between Diet, Gut Microbiota, and Genetic Background by Feng, Wenke, Hu, Junbo, Marsh, Sharon, Yu, Jinsheng, Wu, Chaodong

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the world, and it comprises a spectrum of hepatic abnormalities from…”
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COVID-19 in Wuhan: Sociodemographic characteristics and hospital support measures associated with the immediate psychological impact on healthcare workers by Zhu, Zhou, Xu, Shabei, Wang, Hui, Liu, Zheng, Wu, Jianhong, Li, Guo, Miao, Jinfeng, Zhang, Chenyan, Yang, Yuan, Sun, Wenzhe, Zhu, Suiqiang, Fan, Yebin, Chen, Yuxi, Hu, Junbo, Liu, Jihong, Wang, Wei

“…The outbreak of COVID-19 has laid unprecedented threats and challenges to health workers (HWs) in Wuhan, China. We aimed to assess the sociodemographic…”
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SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis by Wang, Guihua, Long, Jie, Gao, Yuan, Zhang, Weina, Han, Fei, Xu, Chuan, Sun, Li, Yang, Shun-Chin, Lan, Jingqin, Hou, Zhenlin, Cai, Zhen, Jin, Guoxiang, Hsu, Che-Chia, Wang, Yu-Hui, Hu, Junbo, Chen, Tsai-Yu, Li, Hongyu, Lee, Min Gyu, Lin, Hui-Kuan

“…The serine/threonine kinase Akt plays a central role in cell proliferation, survival and metabolism, and its hyperactivation is linked to cancer progression…”
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Jagged 2 inhibition attenuates hypoxia-induced mitochondrial damage and pulmonary hypertension through Sirtuin 1 signaling by Liu, Hanhan, Pan, Zhou, Wu, Xiaofeng, Gong, Cheng, Hu, Junbo

“…Notch pathway has played a significant role in the pathophysiology of pulmonary hypertension (PH). However, the role of Jagged 2 (Jag2), one ligand of Notch,…”
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The biodiversity Composition of Microbiome in Ovarian Carcinoma Patients by Zhou, Bo, Sun, Chaoyang, Huang, Jia, Xia, Meng, Guo, Ensong, Li, Na, Lu, Hao, Shan, Wanying, Wu, Yifan, Li, Yuan, Xu, Xiaoyan, Weng, Danhui, Meng, Li, Hu, Junbo, Gao, Qinglei, Ma, Ding, Chen, Gang

“…Ovarian carcinoma is caused by multiple factors, but its etiology associated with microbes and infection is unknown. Using 16S rRNA high-throughput sequencing…”
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A universal optical aptasensor for antibiotics determination based on a new high-efficiency Förster resonance energy transfer pair by Hu, Junbo, Chen, Pengfei, Zhang, Longsheng, Sun, Pengfei, Huang, Yanqin, Liu, Xingfen, Fan, Quli

“…A novel “turn-on” aptasensor for kanamycin (Kana) detection based on a new Förster resonance energy transfer (FRET) pair is reported. A new organic small…”
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MCP-1/CCR-2 axis in adipocytes and cancer cell respectively facilitates ovarian cancer peritoneal metastasis by Sun, Chaoyang, Li, Xi, Guo, Ensong, Li, Na, Zhou, Bo, Lu, Hao, Huang, Jia, Xia, Meng, Shan, Wanying, Wang, Beibei, Li, Kezhen, Weng, Danhui, Xu, Xiaoyan, Gao, Qinglei, Wang, Shixuan, Hu, Junbo, Lu, Yiling, Mills, Gordon B., Chen, Gang

“…Ovarian cancer selective metastasizes to the omentum contributing to the poor prognosis associated with ovarian cancer. However, the mechanism underlining this…”
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TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling by Hou, Zhenlin, Guo, Kaixuan, Sun, Xuling, Hu, Fuqing, Chen, Qianzhi, Luo, Xuelai, Wang, Guihua, Hu, Junbo, Sun, Li

“…Cellular senescence is a state of irreversible cell growth arrest and senescence cells permanently lose proliferation potential. Induction of cellular…”
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An Optimal Approach for Laparoscopic D3 Lymphadenectomy Plus Complete Mesocolic Excision (D3+CME) for Right-Sided Colon Cancer by Xie, Daxing, Yu, Chaoran, Gao, Chun, Osaiweran, Hasan, Hu, Junbo, Gong, Jianping

“…Background It is common knowledge that high ligation of blood vessels at the D3 level and complete mesocolic excision (CME) are two critical points of right…”
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StainNet: A Fast and Robust Stain Normalization Network by Kang, Hongtao, Luo, Die, Feng, Weihua, Zeng, Shaoqun, Quan, Tingwei, Hu, Junbo, Liu, Xiuli

“…Stain normalization often refers to transferring the color distribution to the target image and has been widely used in biomedical image analysis. The…”
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Design and experiment of electromagnetic-hydraulic-rubber integrated vibration isolator by Chai, Kai, Liu, Shuyong, Hu, Junbo

“…Low-frequency radiated noise, characterized by a distinctive “acoustic fingerprint” is generated when vibrations from marine machinery propagate through a…”
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EZH2-triggered methylation of SMAD3 promotes its activation and tumor metastasis by Huang, Changsheng, Hu, Fuqing, Song, Da, Sun, Xuling, Liu, Anyi, Wu, Qi, She, Xiaowei, Chen, Yaqi, Chen, Lisheng, Hu, Fayong, Xu, Feng, Luo, Xuelai, Feng, Yongdong, Yang, Xiangping, Hu, Junbo, Wang, Guihua

“…SMAD3 plays a central role in cancer metastasis, and its hyperactivation is linked to poor cancer outcomes. Thus, it is critical to understand the upstream…”
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The autophagy-independent role of BECN1 in colorectal cancer metastasis through regulating STAT3 signaling pathway activation by Hu, Fuqing, Li, Geng, Huang, Changsheng, Hou, Zhenlin, Yang, Xi, Luo, Xuelai, Feng, Yongdong, Wang, Guihua, Hu, Junbo, Cao, Zhixin

“…BECN1 is a critical regulator of autophagy, which plays important roles in tumor formation and metastasis. However, the autophagy-independent role of BECN1 and…”
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A Frameshift RBM10 Variant Associated With TARP Syndrome by Daicheng, Han, Shiwen, Xia, Jingxuan, Zhang, Junbo, Hu, Bo, Wang

“…TARP syndrome is a rare X-linked genetic condition caused by mutations in the RBM10 gene. Primary clinical characteristics of TARP syndrome include Talipes…”
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Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway by Wang, Guihua, Fu, Yinjia, Hu, Fuqing, Lan, Jinqing, Xu, Feng, Yang, Xi, Luo, Xuelai, Wang, Jing, Hu, Junbo

“…Brahma-related gene-1 (BRG1) is the specific ATPase of switch/sucrose nonfermentable chromatin-remodeling complex that is aberrantly expressed or mutated in…”
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KDM4B facilitates colorectal cancer growth and glucose metabolism by stimulating TRAF6-mediated AKT activation by Li, Haijie, Lan, Jingqin, Wang, Guihua, Guo, Kaixuan, Han, Caishun, Li, Xiaolan, Hu, Junbo, Cao, Zhixin, Luo, Xuelai

“…Histone lysine demethylase 4B (KDM4B) has been implicated in various pathological processes and human diseases. Glucose metabolism is the main pattern of…”
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